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Check prices for these dates

Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

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Our top choices for San Francisco hotels

A balcony with wicker chairs and a view of the cityscape.

1. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,389 reviews)
"Great location and breakfast buffet was great"
United States
Luis
The price is 2.506.997 ₫
2.757.697 ₫ total
includes taxes & fees
9 Nov - 10 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

2. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,012 reviews)
"I enjoyed my stay at this hotel, great location , breakfast was fresh every morning, room was clean and the staff was friendly. I definitely would be staying here again.."
United States
SHARROW
The price is 3.050.826 ₫
3.355.909 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Courtyard by Marriott Panama Multiplaza Mall
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

3. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,001 reviews)
"Great stay!"
United States
ANDRELL
The price is 3.232.706 ₫
3.555.976 ₫ total
includes taxes & fees
16 Oct - 17 Oct
Aloft by Marriott Panama
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

4. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,779 reviews)
"Nice place, great pool area and great central location.."
United States
benjamin
The price is 4.227.925 ₫
4.650.718 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
A covered outdoor seating area with a view of a city skyline and water.

5. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,245 reviews)
"I love the breakfast with it's increible view of the bay"
United States
Milton
The price is 2.803.307 ₫
2.803.307 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Plaza Paitilla Inn Hotel
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

6. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,122 reviews)
"The breakfast was great and the rooms were comfortable"
United States
Armando
The price is 3.930.474 ₫
4.323.470 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Las Americas Golden Tower Panama
A buffet with various food items and a decorative plant.

7. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,002 reviews)
"Clean rooms, comfy bed, helpful staff! Breakfast buffet was very complete with different options"
United States
Nicole
The price is 4.508.196 ₫
4.959.016 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Sheraton Grand Panama
A poolside area with lounge chairs and a view of the ocean.

8. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,006 reviews)
"Nice hotel-friendly staff"
United States
Detra Dorsey
The price is 7.223.462 ₫
7.945.808 ₫ total
includes taxes & fees
7 Nov - 8 Nov
JW Marriott Panama
A modern building with a glass facade, a curved structure, and a flat roof.

9. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,734 reviews)
"Location is wonderful."
United States
Jorge Luis
The price is 2.250.322 ₫
2.475.354 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

10. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (687 reviews)
"Great place!"
United States
david
The price is 5.096.784 ₫
5.606.462 ₫ total
includes taxes & fees
29 Oct - 30 Oct
Residence Inn by Marriott Panama City
A modern outdoor swimming pool with a clear view of a tall building in the background.

11. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (38 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is 4.004.986 ₫
4.405.485 ₫ total
includes taxes & fees
9 Nov - 10 Nov
Dovle Residences by HMS-Preferred Member
Balcony

12. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (66 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is 2.900.626 ₫
3.837.489 ₫ total
includes taxes & fees
13 Oct - 14 Oct
San Francisco by Wynwood House
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

13. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (236 reviews)
"very nice place to stay"
United States
purabi
The price is 968.647 ₫
4.692.766 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Boutique Apartments Panamá Coco del Mar
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

14. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is 1.159.842 ₫
5.241.564 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Living 73 Panamá by Boutique Apartments
A rooftop pool with lounge chairs, offering a city view.

15. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (49 reviews)
"Staff was great. Room has spectacular views. Air conditioning was great, super quiet in the bedroom. Rooftop pool and patio was delightful. Loved our stay!"
Canada
Gary
The price is 875.043 ₫
3.792.944 ₫ total
includes taxes & fees
19 Oct - 20 Oct
Boutique Apartments Atlapa
A high-rise hotel with a modern design, featuring a prominent entrance and multiple balconies.

16. Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is 2.286.102 ₫
2.514.712 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Modern Apartments at the Hub City views
A modern hotel pool area with a circular hot tub, lounge chairs, and a view of the city skyline.

17. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (4 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is 1.980.502 ₫
6.134.381 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Wanders Panama by Boutique Apartments
A modern living room with a city view, green chairs, a sofa, and hanging light fixtures.

18. Wanders & Yoo

Wanders & Yoo
4.0 star property
San Francisco
7.4 out of 10, Good, (12 reviews)
"Great property, luxurious. I would visit again."
United States
Sean
The price is 8.075.169 ₫
8.882.686 ₫ total
includes taxes & fees
20 Oct - 21 Oct
Wanders & Yoo
A hotel room with a bed, a desk, and a chair. There is a window with a view of palm trees and tall buildings.

19. Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
8.0 out of 10, Very good, (15 reviews)
"Really great location, very kind and helpful staff. Some things may need some updating, but i would not think twice before booking the place!"
United States
Brett
The price is 1.528.782 ₫
1.681.660 ₫ total
includes taxes & fees
23 Oct - 24 Oct
Casa Orquídea
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

20. Pty Loft-style 1br Cincuentenario Bay

Pty Loft-style 1br Cincuentenario Bay
2.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is 2.782.586 ₫
3.948.772 ₫ total
includes taxes & fees
13 Oct - 14 Oct
Pty Loft-style 1br Cincuentenario Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A covered outdoor seating area with a view of a city skyline and water.
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,245 reviews
View
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
9.0
Wonderful
1,012 reviews
View
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
Aloft by Marriott Panama
3.5 star property
8.8
Excellent
1,001 reviews
View
Balcony
San Francisco by Wynwood House
3.0 star property
9.2
Wonderful
66 reviews
View
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.
Residence Inn by Marriott Panama City
4.0 star property
9.2
Wonderful
687 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

Top San Francisco Hotel Reviews

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

10/10 Excellent
"Nice hotel, great service and great staff"
James 1-night trip
Posted less than an hour ago
Crowne Plaza Panama Airport by IHG

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 323 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Via Espana might be the perfect way to find that souvenir you've been looking for. Calle 50 and Pacific Center are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Bingo 90, Soho City Center and National Shrine of the Heart of Mary. When you're sightseeing in Panama City, Panama Viejo Museum and Multicentro Panama are also worth a stop.

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