
Search Hotels in Sanctuary, Sanibel
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Sanctuary hotels

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort21.8 km from Sanctuary
9.0 out of 10, Wonderful, (1,207 reviews)
The price is 7.454.839 ₫
8.891.187 ₫ total
includes taxes & fees
10 Feb - 11 Feb

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG23.1 km from Sanctuary
9.4 out of 10, Exceptional, (1,006 reviews)
The price is 4.310.356 ₫
4.806.047 ₫ total
includes taxes & fees
22 Feb - 23 Feb

Dolphin Key Resort
Dolphin Key Resort23.8 km from Sanctuary
8.8 out of 10, Excellent, (1,226 reviews)
The price is 4.284.390 ₫
4.777.095 ₫ total
includes taxes & fees
6 Mar - 7 Mar

Allure Suites
Allure Suites27.2 km from Sanctuary
7.8 out of 10, Good, (1,008 reviews)
The price is 2.986.090 ₫
3.329.490 ₫ total
includes taxes & fees
27 Feb - 28 Feb

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach21.5 km from Sanctuary
8.8 out of 10, Excellent, (1,004 reviews)
The price is 6.192.891 ₫
6.905.138 ₫ total
includes taxes & fees
7 Mar - 8 Mar

Matlacha Tiny Village
Matlacha Tiny Village18.8 km from Sanctuary
8.8 out of 10, Excellent, (274 reviews)
The price is 3.248.347 ₫
5.569.707 ₫ total
includes taxes & fees
9 Feb - 10 Feb

Doubletree by Hilton Fort Myers at Bell Tower Shops
Doubletree by Hilton Fort Myers at Bell Tower Shops30.8 km from Sanctuary
8.8 out of 10, Excellent, (1,006 reviews)
The price is 4.769.435 ₫
5.317.919 ₫ total
includes taxes & fees
15 Feb - 16 Feb

The Anchor Inn
The Anchor InnMid Island, 12.8 km from Sanctuary
The price is 6.509.676 ₫
7.647.779 ₫ total
includes taxes & fees
10 Feb - 11 Feb

Matlacha on Shoreview
Matlacha on Shoreview20.2 km from Sanctuary
9.6 out of 10, Exceptional, (231 reviews)
The price is 2.570.634 ₫
4.603.383 ₫ total
includes taxes & fees
5 Mar - 6 Mar

Bike to Dtwn: Home w/ Hot Tub & BBQ in Cape Coral
Bike to Dtwn: Home w/ Hot Tub & BBQ in Cape Coral23.1 km from Sanctuary
The price is 2.544.668 ₫
8.864.533 ₫ total
includes taxes & fees
15 Feb - 16 Feb

Lazy Cuckoo Inn
Lazy Cuckoo Inn22.1 km from Sanctuary
8.8 out of 10, Excellent, (243 reviews)
The price is 2.752.396 ₫
3.908.533 ₫ total
includes taxes & fees
9 Feb - 10 Feb

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
Holiday Inn Express Cape Coral-Fort Myers Area by IHG23.9 km from Sanctuary
9.2 out of 10, Wonderful, (1,211 reviews)
The price is 4.180.526 ₫
4.661.416 ₫ total
includes taxes & fees
22 Feb - 23 Feb

TriLuxe Inn & Studios
TriLuxe Inn & Studios22.7 km from Sanctuary
8.4 out of 10, Very good, (18 reviews)
The price is 2.757.589 ₫
3.914.322 ₫ total
includes taxes & fees
9 Feb - 10 Feb

Margaritaville Beach Resort Fort Myers
Margaritaville Beach Resort Fort Myers21.6 km from Sanctuary
9.0 out of 10, Wonderful, (1,858 reviews)
The price is 7.688.533 ₫
9.875.688 ₫ total
includes taxes & fees
9 Feb - 10 Feb

Hilton Garden Inn Ft Myers
Hilton Garden Inn Ft Myers29.5 km from Sanctuary
8.8 out of 10, Excellent, (1,007 reviews)
The price is 5.380.155 ₫
5.998.873 ₫ total
includes taxes & fees
15 Feb - 16 Feb

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway19.9 km from Sanctuary
8.0 out of 10, Very good, (1,026 reviews)
The price is 4.549.243 ₫
5.072.405 ₫ total
includes taxes & fees
1 Mar - 2 Mar

Latitude 26 Waterfront Resort & Marina
Latitude 26 Waterfront Resort & Marina22 km from Sanctuary
8.6 out of 10, Excellent, (938 reviews)
The price is 7.659.970 ₫
8.540.996 ₫ total
includes taxes & fees
7 Mar - 8 Mar

Sanibel Island Beach Resort
Sanibel Island Beach ResortMid Island, 13.1 km from Sanctuary
9.2 out of 10, Wonderful, (1,591 reviews)
The price is 9.841.114 ₫
11.621.992 ₫ total
includes taxes & fees
9 Feb - 10 Feb

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral30.1 km from Sanctuary
8.6 out of 10, Excellent, (817 reviews)
The price is 4.180.526 ₫
4.661.286 ₫ total
includes taxes & fees
15 Feb - 16 Feb

Residence Inn by Marriott Fort Myers Sanibel
Residence Inn by Marriott Fort Myers Sanibel19.3 km from Sanctuary
8.6 out of 10, Excellent, (1,000 reviews)
The price is 5.998.146 ₫
6.687.932 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Sanctuary
Find the best Sanctuary areas for the activities you enjoy most.
West End
If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.
Mid Island
If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.
East End
While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates
While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.
Shell Harbor
While Shell Harbor isn't home to many top sights, Sanibel Moorings Botanical Gardens and Sanibel Sea School are some notable places to visit nearby.
Top Sanctuary Hotel Reviews

Pointe Estero Beach Resort
10/10 Excellent

Allure Suites
10/10 Excellent































































