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Top Trending Hotels Near Sanford USD Medical Center

Interior detail
Hotel On Phillips

Hotel On Phillips

2.5 star property
Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center
9.6 out of 10, Exceptional, (1285)
"Very clean, beautiful hotel"
United States
Charlie
Hotel On Phillips
Free daily continental breakfast
Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

3.0 star property
Mall District, 2.9 km from Sanford USD Medical Center
9.6 out of 10, Exceptional, (1001)
"Rooms were great!!"
United States
Mike
Clubhouse Hotel Suites Sioux Falls
Terrace/patio
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

Home2 Suites By Hilton Sioux Falls/Sanford Medical Center

3.0 star property
University Heights, 0.1 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (583)
"Great stay, love the skybridge to the hospital!"
United States
Drew
The price is 2.721.487 ₫
3.038.214 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Home2 Suites By Hilton Sioux Falls/Sanford Medical Center
Meeting facility
Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown

4.0 star property
Downtown Sioux Falls, 2.4 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (152)
"Room was very clean, great overall stay."
United States
Destiny
The price is 3.653.385 ₫
4.165.942 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Canopy By Hilton Sioux Falls Downtown
Presidential Suite, 1 King Bed, Jetted Tub (Balcony) | Living area | 42-inch LCD TV with cable channels, TV, pay films
Hilton Garden Inn Sioux Falls Downtown

Hilton Garden Inn Sioux Falls Downtown

3.0 star property
Downtown Sioux Falls, 2 km from Sanford USD Medical Center
9.0 out of 10, Wonderful, (879)
"Under construction but staff adapted and accommodated very well. Room was clean and quiet. Perfect location "
United States
Joseph
The price is 2.885.980 ₫
3.324.099 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hilton Garden Inn Sioux Falls Downtown
Porch
Historic Victorian Inn

Historic Victorian Inn

3.0 star property
Cathedral, 1.4 km from Sanford USD Medical Center
8.8 out of 10, Excellent, (56)
"It was a great place to stay and super interesting."
United States
Kathy
The price is 3.309.804 ₫
4.063.341 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Historic Victorian Inn
Exterior
Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG

3.0 star property
Downtown Sioux Falls, 1.8 km from Sanford USD Medical Center
8.6 out of 10, Excellent, (1002)
"Always a great stay. "
United States
Shawn
The price is 2.715.389 ₫
3.545.824 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Sioux Falls-City Centre by IHG
Lobby
Sheraton Sioux Falls Hotel & Convention Center

Sheraton Sioux Falls Hotel & Convention Center

4.0 star property
Northwest Sioux Falls, 2.8 km from Sanford USD Medical Center
8.6 out of 10, Excellent, (1001)
"Great hotel. Staff was excellent "
United States
Kristina
The price is 2.554.575 ₫
2.855.095 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Sheraton Sioux Falls Hotel & Convention Center
Exterior
Country Inn & Suites by Radisson, Sioux Falls, SD

Country Inn & Suites by Radisson, Sioux Falls, SD

3.0 star property
Downtown Sioux Falls, 1.9 km from Sanford USD Medical Center
8.4 out of 10, Very good, (1150)
"It was a great place to stay!"
United States
Trinity
The price is 2.554.575 ₫
2.855.095 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Country Inn & Suites by Radisson, Sioux Falls, SD
Free daily continental breakfast
The Center Inn

The Center Inn

2.5 star property
All Saints, 2.3 km from Sanford USD Medical Center
8.4 out of 10, Very good, (699)
"Clean room and friendly staff."
United States
Betty
The Center Inn
3 indoor pools, open 9:00 AM to 10:00 PM, pool loungers
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

3.0 star property
Northwest Sioux Falls, 2.9 km from Sanford USD Medical Center
7.8 out of 10, Good, (1455)
"Everything was wonderful: Airport shuttle, room, breakfast, waterpark area, staff. What a great stay!"
United States
Christine
The price is 1.577.826 ₫
1.783.601 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Room, 2 Queen Beds | Desk, free WiFi, wheelchair access
Valley Inn

Valley Inn

2.5 star property
University Heights, 0.1 km from Sanford USD Medical Center
7.6 out of 10, Good, (1000)
"Room was clean, staff was friendly, very convenient location "
United States
Theresa
Valley Inn
Pool
Ramada by Wyndham Sioux Falls Arpt & Suites

Ramada by Wyndham Sioux Falls Arpt & Suites

2.0 star property
Northwest Sioux Falls, 2.9 km from Sanford USD Medical Center
7.0 out of 10, Good, (51)
"Great "
United States
Jorge
Ramada by Wyndham Sioux Falls Arpt & Suites
Lobby
Ramada by Wyndham Sioux Falls

Ramada by Wyndham Sioux Falls

2.0 star property
2.7 km from Sanford USD Medical Center
5.6 out of 10, (1002)
"Clean room, great breakfast!, courteous staff....definately recommend "
United States
Juliet
The price is 1.254.879 ₫
1.429.329 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Ramada by Wyndham Sioux Falls
Front of property
WoodSpring Suites Sioux Falls

WoodSpring Suites Sioux Falls

2.5 star property
2.9 km from Sanford USD Medical Center
5.2 out of 10, (60)
"The price was good, the cleanliness was better than other cheap hotels I've stayed in. My primary complaint was the slow internet speeds. There was also damage that had not been repaired from prior guests."
United States
Trent
The price is 1.819.047 ₫
2.048.220 ₫ total
includes taxes & fees
7 Dec - 8 Dec
WoodSpring Suites Sioux Falls
Terrace/patio
Hyatt Place Sioux Falls South

Hyatt Place Sioux Falls South

3.0 star property
Mall District, 3.8 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (1001)
"Great location for travel. Various dining options close by."
United States
Russell
The price is 3.179.378 ₫
3.540.503 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Place Sioux Falls South
Free cots/infant beds, free WiFi, bed sheets
Staybridge Suites Sioux Falls Southwest by IHG

Staybridge Suites Sioux Falls Southwest by IHG

3.0 star property
South Sioux Falls, 5.3 km from Sanford USD Medical Center
9.6 out of 10, Exceptional, (455)
"We choose to continue to stay at the Sioux Falls Staybridge because of the excellent service we receive!"
United States
Vicki
The price is 2.452.503 ₫
2.743.137 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Sioux Falls Southwest by IHG
Room, Multiple Beds, Accessible, Non Smoking | Desk, laptop workspace, soundproofing, iron/ironing board
Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex

2.5 star property
Northwest Sioux Falls, 6 km from Sanford USD Medical Center
9.6 out of 10, Exceptional, (884)
"We had a quick overnight as part of a longer trip but the hotel was very clean, rooms were comfortable and breakfast got us on the road. Would stay here again! "
United States
chris
The price is 2.491.040 ₫
2.785.396 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites at Sanford Sports Complex
Front of property – evening/night
Hampton Inn Sioux Falls

Hampton Inn Sioux Falls

2.5 star property
Mall District, 3.2 km from Sanford USD Medical Center
9.2 out of 10, Wonderful, (1000)
"Great location and a friendly staff "
United States
Dan
The price is 2.572.502 ₫
2.874.760 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hampton Inn Sioux Falls
Lobby sitting area
Comfort Inn & Suites Avera Southwest

Comfort Inn & Suites Avera Southwest

2.5 star property
South Sioux Falls, 5.6 km from Sanford USD Medical Center
9.4 out of 10, Exceptional, (1001)
"The room was very clean, the beds were comfortable..enjoyed our stay:)"
United States
Valarie
The price is 2.679.008 ₫
2.991.598 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Avera Southwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sanford USD Medical Center Hotel Reviews

Hotels near other Sanford USD Medical Center attractions

Sioux Empire Medical Museum

You can spend time studying the exhibits at Sioux Empire Medical Museum during your travels in Sioux Falls. In the area, take in the entertainment choices and beautiful waterfalls.
See properties

University of Sioux Falls

4.1/5 (170 reviews)
Explore the campus of University of Sioux Falls during your trip to Sioux Falls. Attend a sporting event or discover the area's beautiful waterfalls.
See properties

Frequently asked questions

What's the area like around Sanford USD Medical Center?
Sanford USD Medical Center is located in a welcoming area of Sioux Falls known for its beautiful waterfalls and sporting events. If you're looking for a convenient place to stay, take a look at the 112 hotels and other accommodation options you'll find within a mile.
How many hotels should I expect to find close to Sanford USD Medical Center?
Expedia has 112 hotels and other accommodation options within a mile from Sanford USD Medical Center.
If I need to cancel the hotel reservation for my stay near Sanford USD Medical Center, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to get the best deals near Sanford USD Medical Center.
What can I see and do near Sanford USD Medical Center?
Study the collections at Washington Pavilion of Arts and Science, Center for Western Studies or Pettigrew Home and Museum. Spend some time wandering around Falls Park, Sherman Park and Veterans' Memorial Park. Create some family memories at Delbridge Museum of Natural History, Great Plains Zoo and Thunder Road Family Fun Park while you're exploring the area around Sanford USD Medical Center.

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