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Our top choices for Santa Ana hotels

1. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is 810.696 ₫
891.766 ₫ total
includes taxes & fees
15 Aug - 16 Aug
Hostal La Cigarra

2. Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (104 reviews)
"Always an amazing stay"
United States
chris
The price is 1.760.062 ₫
2.718.318 ₫ total
includes taxes & fees
18 Aug - 19 Aug
Casco View Apartments

3. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (196 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is 762.694 ₫
2.403.594 ₫ total
includes taxes & fees
18 Aug - 19 Aug
Hotel República

4. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is 3.467.975 ₫
4.962.073 ₫ total
includes taxes & fees
24 Aug - 25 Aug
La Manzana Barrio Vivo by Wynwood

5. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is 704.025 ₫
774.428 ₫ total
includes taxes & fees
14 Sept - 15 Sept
Hotel Riazor

6. Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is 3.028.829 ₫
3.331.712 ₫ total
includes taxes & fees
15 Aug - 16 Aug
Room-sofa Bed Stay Rooftop Pool & Gym, A

7. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (2 reviews)
"It is what you would expect for the $30/ night. Clean bed, and room, a/c worked well, limited water for showers at times, limited hot water. Great location for walking around close to Casco Viejo."
United States
William
The price is 704.025 ₫
774.428 ₫ total
includes taxes & fees
14 Sept - 15 Sept
Hotel Caracas - Casco Viejo

8. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is 639.881 ₫
703.765 ₫ total
includes taxes & fees
29 Aug - 30 Aug
ART CASCO The Hotel

9. Hotel Caribe

Hotel Caribe
3.0 star property
Calidonia, 1.2 km from Santa Ana
7.8 out of 10, Good, (329 reviews)
"Hotel clean and staff is great the facilities need a little updating there is no good bilingual help closed to everything my stay was great"
United States
dave
The price is 1.089.409 ₫
1.198.350 ₫ total
includes taxes & fees
4 Sept - 5 Sept
Hotel Caribe

10. Best Western El Dorado Panama Hotel

Best Western El Dorado Panama Hotel
3.0 star property
Bethania, 5.5 km from Santa Ana
9.0 out of 10, Wonderful, (768 reviews)
"The room was well kept, staff was very friendly, helpful and professional."
United States
Romain
The price is 2.607.500 ₫
2.868.250 ₫ total
includes taxes & fees
21 Aug - 22 Aug
Best Western El Dorado Panama Hotel

11. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,223 reviews)
"Great breakfast, location excellent, staff friendly and spacious room"
United States
Gilberto
The price is 2.991.820 ₫
3.291.002 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Plaza Paitilla Inn Hotel

12. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,810 reviews)
"excellent choice near the airport with a good price clean pool, good food"
United States
Elizabeth
The price is 2.822.914 ₫
3.105.205 ₫ total
includes taxes & fees
27 Aug - 28 Aug
Riande Aeropuerto Hotel & Casino

13. ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (181 reviews)
"Excellent spot, polite staff, at walking distance from de city."
United States
Juan
The price is 2.666.847 ₫
3.461.567 ₫ total
includes taxes & fees
28 Aug - 29 Aug
ORHO Hotel Boutique 15 Minutes from PTY Airport

14. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,671 reviews)
"Good hotel"
United States
Geraldeen
The price is 3.289.860 ₫
3.791.172 ₫ total
includes taxes & fees
12 Sept - 13 Sept
Crowne Plaza Panama Airport by IHG

15. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (793 reviews)
"A lovely friendly hotel with excellent staff"
United Kingdom
Ann
The price is 6.782.108 ₫
7.460.319 ₫ total
includes taxes & fees
20 Aug - 21 Aug
American Trade Hotel

16. Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (322 reviews)
"Great Location , helpful staff"
United States
David
The price is 2.433.580 ₫
2.676.938 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Tantalo Hotel

17. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,802 reviews)
"Great stay breakfast was amazing will definitely visit again."
United States
Towona
The price is 3.589.001 ₫
3.947.901 ₫ total
includes taxes & fees
13 Sept - 14 Sept
Hotel Riu Plaza Panama

18. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,213 reviews)
"This is an exceptionally nice hotel, location, service and amenities were all on point."
United States
Geraldeen
The price is 2.312.840 ₫
2.544.124 ₫ total
includes taxes & fees
31 Aug - 1 Sept
The Executive Hotel

19. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
El Cangrejo, 3.4 km from Santa Ana
8.8 out of 10, Excellent, (573 reviews)
"Breakfast was great, location offered beautiful scenery with higher floor room."
United States
Solomon
The price is 2.411.819 ₫
2.653.001 ₫ total
includes taxes & fees
23 Aug - 24 Aug
Torres de Alba Hotel & Suites

20. Hotel Marparaiso

Hotel Marparaiso
3.0 star property
Calidonia, 1.7 km from Santa Ana
7.8 out of 10, Good, (194 reviews)
"The location was ideal for walking around."
United States
Erold
The price is 948.087 ₫
1.043.000 ₫ total
includes taxes & fees
20 Aug - 21 Aug
Hotel Marparaiso
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
104 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.6
Good
18 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.8
196 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
How many hotels can I expect to find in Santa Ana?
Expedia has 134 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

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