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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (100 reviews)
"Always an amazing stay"
United States
chris
The price is 2.338.418 ₫
3.361.200 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Casco View Apartments

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (72 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is 726.781 ₫
799.459 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Hostal La Cigarra

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is 710.046 ₫
781.051 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Hotel Riazor

Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is 2.739.779 ₫
3.013.757 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Room-sofa Bed Stay Rooftop Pool & Gym, A

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (195 reviews)
"Very good ."
United States
Denice
The price is 769.216 ₫
2.424.018 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Hotel República

La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is 1.577.880 ₫
2.458.863 ₫ total
includes taxes & fees
2 Jul - 3 Jul
La Manzana Barrio Vivo by Wynwood

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is 968.244 ₫
1.065.068 ₫ total
includes taxes & fees
30 Jun - 1 Jul
ART CASCO The Hotel

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,814 reviews)
"The pool area is very nice"
United States
Matthew
The price is 3.105.805 ₫
3.416.386 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Riande Aeropuerto Hotel & Casino

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,604 reviews)
"Great place to stay, restaurant is great also"
United States
Janet
The price is 3.339.846 ₫
3.847.397 ₫ total
includes taxes & fees
9 Jul - 10 Jul
Crowne Plaza Panama Airport by IHG

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (78 reviews)
"Really good food, nice staff it was the best service! "
United States
junier
The price is 4.207.680 ₫
4.628.448 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Villa Caprichosa

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (142 reviews)
"Lovely property, staff was always smiling and it's close to restaurants."
United States
Luis
The price is 2.689.655 ₫
3.491.172 ₫ total
includes taxes & fees
30 Jun - 1 Jul
ORHO Hotel Boutique 15 Minutes from PTY Airport

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Campo Alegre, 3.4 km from Santa Ana
8.8 out of 10, Excellent, (236 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is 3.339.846 ₫
3.673.831 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Renaissance Panama City Hotel

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,658 reviews)
"Great Location, good food."
United States
Yohan
The price is 3.719.559 ₫
4.091.515 ₫ total
includes taxes & fees
2 Jul - 3 Jul
Hotel Riu Plaza Panama

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
24.7 km from Santa Ana
8.0 out of 10, Very good, (782 reviews)
"Great place to stay."
United States
Oscar
The price is 3.763.244 ₫
4.139.568 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Gamboa Rainforest Reserve

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este, 10.2 km from Santa Ana
9.2 out of 10, Wonderful, (309 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is 2.343.152 ₫
3.966.002 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Arcadia Condo Suites

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (440 reviews)
"Very nice small hotel, comfortable excellent location on Amador Causeway. Close to Albrook Mall, Casco, Viejo…"
United States
David
The price is 1.978.662 ₫
2.176.528 ₫ total
includes taxes & fees
15 Jul - 16 Jul
The Beach House

Summit Rainforest Golf Resort & All Inclusive

Summit Rainforest Golf Resort & All Inclusive
4.0 star property
14.5 km from Santa Ana
8.4 out of 10, Very good, (1,000 reviews)
"Excellent location and clean hotel"
United States
Mark
The price is 5.609.363 ₫
6.170.299 ₫ total
includes taxes & fees
24 Jul - 25 Jul
Summit Rainforest Golf Resort & All Inclusive

The District Hotel Panama

The District Hotel Panama
3.0 star property
El Cangrejo, 3.8 km from Santa Ana
8.4 out of 10, Very good, (5 reviews)
"The rooms are clean, the bed was very comfortable. They have been updating the rooms to include new beds. Breakfast is served on time, and is mostly Panamanian cuisine. They staff is very helpful. The area is walkable with stores and restaurants nearby. I would stay again."
United States
Terry
The price is 1.887.144 ₫
2.075.858 ₫ total
includes taxes & fees
30 Jun - 1 Jul
The District Hotel Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.0 out of 10, Very good, (258 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is 2.041.383 ₫
2.245.521 ₫ total
includes taxes & fees
30 Jun - 1 Jul
MARINN Tropical Vibes Hotel

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
7.5 km from Santa Ana
8.0 out of 10, Very good, (1,001 reviews)
"This is an excellent hotel and would highly recommend."
United States
Shernon
The price is 5.420.018 ₫
5.962.020 ₫ total
includes taxes & fees
18 Jul - 19 Jul
The Westin Playa Bonita Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
100 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
72 reviews
View
Beach shuttle
Hotel República
2.0 star property
6.8
195 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Bar (on property)
Hotel Riazor
3.0 star property
3.8
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
How many hotels can I expect to find in Santa Ana?
Expedia has 120 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

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