Santa Cruz Island Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Sig

Top hotels in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo, Puerto Ayora, Galapagos
Fully refundableReserve now, pay when you stay
The price is 4.078.728 ₫ per night from 22 Aug to 23 Aug
4.078.728 ₫
4.078.728 ₫ total
22 Aug - 23 Aug
9/10 Wonderful! (355 reviews)
"Great place for the money"

Reviewed on 13 Aug 2025

Hotel Fiesta
Hotel Cucuve

Hotel Cucuve

4 out of 5
Charles Binford 083 y Ave Charles Darwin, Puerto Ayora
The price is 5.779.840 ₫ per night from 20 Aug to 21 Aug
5.779.840 ₫
6.357.824 ₫ total
20 Aug - 21 Aug
9.8/10 Exceptional! (256 reviews)
Great hotel in Puerto Ayuro
"Excellent location, clean, friendly, and great breakfast. Highly recommend. Only caveat- the outdoor area on the water shown in photos is actually a couple blocks from the rest of the hotel. Not a big deal, but I was surprised."

Reviewed on 2 Aug 2025

Hotel Cucuve
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador, Puerto Ayora, Galapagos
8.8/10 Excellent! (162 reviews)
"Beautiful and spacious family room. Good breakfast and the staff is courteous. I highly recommend this hotel."

Reviewed on 14 Aug 2025

Get rates
Hotel el descanso del Guia
See all 202 properties in Santa Cruz Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

El Garrapatero Beach

El Garrapatero Beach

Why not spend a care-free afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.

El Garrapatero Beach
Las Ninfas Lagoon

Las Ninfas Lagoon

Commune with nature and explore the great outdoors at Las Ninfas Lagoon during your travels in Puerto Ayora. While you're here, you can savour the top-notch restaurants.

Las Ninfas Lagoon

Playa de los Alemanes

If a restful holiday is part of your travel plans, Playa de los Alemanes might be the perfect place to visit during your trip to Puerto Ayora. While you're here, you can savour the top-notch restaurants.

Playa de los Alemanes

Frequently asked questions

How much does a Santa Cruz Island holiday package cost?
From as low as . Yes, you read that right. Our Santa Cruz Island packages are a simple way to stretch your budget. Combine your preferred flights, hotels and rental car and explore this vibrant destination.
How do I get a cheap travel package to Santa Cruz Island?
Simply by bundling. Hotels, rental cars and flights — combine whatever you need into a Santa Cruz Island holiday package to save a ton of cash. Score even more discounts when you include extras such as sightseeing tours to your booking. But that's not the only good part. You have the flexibility to tailor your trip your way. We offer over 550 airlines and 1null000null000 properties throughout the world, so that everyone has an opportunity to travel and fulfil those holiday dreams.
How far in advance should I book my Santa Cruz Island holiday?
Reserving your flight early with Expedia means one less thing to worry about. Many air carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, discount flights to Santa Cruz Island sometimes occur a few weeks before departure.
What does an Expedia Santa Cruz Island travel package include?
Choose from any combination of rental cars, flights and hotels. Once you've made your booking, you can add activities and tours. Want to pick your fare class? That's also easy to do. The choice is yours when it comes to arranging your dream Santa Cruz Island getaway.
What should I know before booking a Santa Cruz Island travel package?
We already have low prices. However, you'll pick up even more savings when you book your hotels, flights and car rentals together. With an Expedia package, you'll always get transparent pricing and a terrific range of choice.
Can I choose my airline with a Santa Cruz Island Expedia holiday package?
You can. We offer more than 550 airline partners globally, so select the carrier that best fits your budget and travelling style.
If I'm not able to travel, can I cancel my Santa Cruz Island holiday package?
Yes, you can. We get that life doesn't always go to plan, so we're here to help if you need to make changes to your Santa Cruz Island holiday package. It may be possible to amend or cancel your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may charge you a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the finer details on change fees.