Search Hotels in Santa Cruz, Nîmes

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Casa Dina

Casa Dina
5.0 star property
27.4 km from Santa Cruz
10.0 out of 10, Exceptional, (19)
"My wife and I recently spent 2 nights at the Casa Dina in one of their beautiful fully equipped studios. Due to last minute travel changes (we were touring Provence by car) we arrived early. We were met by our host Eric who was very welcoming and explained this wasn’t an issue for him due to the previous guests leaving early that morning. Eric continued to show us our accommodation and amenities. We were immediately impressed by the high quality, condition and cleanliness of everything...
United Kingdom
Paul
The price is 3.390.222 ₫
3.939.873 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Casa Dina

Hotel Mas de Boudan

Hotel Mas de Boudan
4.0 star property
Route d'Arles, 5.1 km from Santa Cruz
9.8 out of 10, Exceptional, (18)
"This place is a gem; after a day of touring Nimes, we spent a very quiet night there, had an excellent dinner, and an amazing breakfast. The staff is very friendly and professional; I have some mobility issues, and received help way beyond my expectations. The hotel is very comfortable and quiet."
United States
phillip
The price is 4.042.998 ₫
4.583.188 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Mas de Boudan

La Maison Volver

La Maison Volver
4.0 star property
27.5 km from Santa Cruz
9.2 out of 10, Wonderful, (346)
"Responsive staff and nice location."
United States
Monique
The price is 2.427.475 ₫
2.901.234 ₫ total
includes taxes & fees
16 Dec - 17 Dec
La Maison Volver

Péniche Le Pescalune

Péniche Le Pescalune
28.7 km from Santa Cruz
10.0 out of 10, Exceptional, (1)
The price is 3.103.001 ₫
3.636.592 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Péniche Le Pescalune

Boutique Hôtel Entraigues

Boutique Hôtel Entraigues
4.0 star property
16.7 km from Santa Cruz
9.4 out of 10, Exceptional, (271)
"Great place, very Nice"
United States
Mike
Boutique Hôtel Entraigues

Hôtel Présent - 200m des Arènes de Arles - Encore Mieux

Hôtel Présent - 200m des Arènes de Arles - Encore Mieux
3.0 star property
27.6 km from Santa Cruz
9.2 out of 10, Wonderful, (73)
"Absolutely fantastic hotel, could not recommend more! Great location, beautifully designed rooms, felt like a special stay. "
United Kingdom
Maria
Hôtel Présent - 200m des Arènes de Arles - Encore Mieux

Hôtel du Viaduc

Hôtel du Viaduc
2.0 star property
22 km from Santa Cruz
8.6 out of 10, Excellent, (80)
"Charming hotel with friendly staff, nice pool and garden, five minutes to station and short connections to Arles and Avignon. And a walk across river to neighbour town with more restaurants etc."
Denmark
Anonymous traveller
The price is 2.027.114 ₫
2.318.772 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hôtel du Viaduc

La Demeure

La Demeure
23.6 km from Santa Cruz
10.0 out of 10, Exceptional, (18)
"The hosts are very welcoming and kind and the property is very well decorated. 10/10 - recommended for sure"
France
Jay
La Demeure

Maison Douce Arles

Maison Douce Arles
27.7 km from Santa Cruz
9.4 out of 10, Exceptional, (49)
"The family that run the hotel operation are very nice and accommodating. Very secure parking arrangement and as close to the old city center as you can reasonably drive into. "
United States
Thomas
Maison Douce Arles

Logis Hotel Uzes Pont du Gard

Logis Hotel Uzes Pont du Gard
3.0 star property
15.6 km from Santa Cruz
8.2 out of 10, Very good, (378)
"The hotel is just off the road entering Uzes"
United States
Hao
The price is 1.993.563 ₫
2.295.918 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Logis Hotel Uzes Pont du Gard

Mercure Arles Centre Arenes

Mercure Arles Centre Arenes
4.0 star property
27.8 km from Santa Cruz
9.0 out of 10, Wonderful, (19)
"Right in the centre of Arles. Parking under the hotel is available although the spaces are a bit tight."
United Kingdom
Ian
The price is 2.004.653 ₫
2.436.131 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Mercure Arles Centre Arenes

Hôtel La Muette

Hôtel La Muette
3.0 star property
27.5 km from Santa Cruz
9.2 out of 10, Wonderful, (316)
"Charming hotel, very helpful staff"
Canada
Louis
The price is 2.891.866 ₫
3.332.385 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hôtel La Muette

Hôtel Belesso

Hôtel Belesso
3.0 star property
29.6 km from Santa Cruz
8.8 out of 10, Excellent, (145)
"I stayed in Hotel Belesso while travelling through Provence"
Ireland
Carol
The price is 2.754.236 ₫
3.181.053 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hôtel Belesso

Hôtel Mistral

Hôtel Mistral
3.0 star property
29.9 km from Santa Cruz
9.0 out of 10, Wonderful, (77)
"We had a most pleasant short stay here. Lovely breakfast and welcoming hosts"
United Kingdom
Mark
The price is 2.358.303 ₫
2.745.589 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hôtel Mistral

La Paillère

La Paillère
21.1 km from Santa Cruz
9.0 out of 10, Wonderful, (44)
"Warm welcome, very accommodating hostess and a lovely breakfast. The setting is an idyllic courtyard, and I had a very comfortable stay and I would happily return if I was in the area again."
United Kingdom
Hugh
La Paillère

Hôtel Arles Plaza

Hôtel Arles Plaza
4.0 star property
27.8 km from Santa Cruz
8.6 out of 10, Excellent, (558)
"Good location, great indoor pool."
United States
Debra
The price is 2.021.575 ₫
2.454.744 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hôtel Arles Plaza

Hôtel de l'Amphithéâtre

Hôtel de l'Amphithéâtre
3.0 star property
Nimes City Centre, 4.4 km from Santa Cruz
9.0 out of 10, Wonderful, (387)
"Excellent and welcoming staff. Very good location. The only drawbacks were: the washroom- Very high and slippery tub. Could have used a grab bar for safety. And a small console with drawers wold make fôr a more comfortable room."
United States
Dulce
Hôtel de l'Amphithéâtre

La Regalido

La Regalido
4.0 star property
29.1 km from Santa Cruz
9.0 out of 10, Wonderful, (128)
"Beautiful hotel and very clean. Great restaurants within walking distance. The staff are very attentive. "
United States
Robin
The price is 2.863.790 ₫
3.381.181 ₫ total
includes taxes & fees
17 Dec - 18 Dec
La Regalido

Jules César Hotel & Spa Arles - MGallery Collection

Jules César Hotel & Spa Arles - MGallery Collection
5.0 star property
27.8 km from Santa Cruz
8.8 out of 10, Excellent, (297)
"Excellent location, very clean, helpful staff. I would highly recommend this hotel."
Canada
Lyse
The price is 4.138.457 ₫
4.863.614 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Jules César Hotel & Spa Arles - MGallery Collection

Château de Collias

Château de Collias
5.0 star property
11.8 km from Santa Cruz
10.0 out of 10, Exceptional, (39)
"The setting, history and brilliant decor elevated the hotel to the very highest level. Quiet and luxurious rooms. Thoughtful professional staff. "
Canada
Caroline
The price is 4.525.630 ₫
5.163.497 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Château de Collias
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

Nimes City Centre

Nimes City Centre is noteworthy for its historical sites, and you can make a stop at top attractions like Theater de Nimes and Maison Carree.

Costières

While visiting Costières, you might make a stop by sights like Nimes-Campagne Golf Club and Costieres Stadium.

Quartier Administrations

If you're spending some time in Quartier Administrations, Musée de la Romanité and Nimes Museum of Fine Arts are top sights worth seeing.

Kennedy

When in Kennedy, you can plan a visit to Maison Carree and Musée de la Romanité, some noteworthy sights in the nearby area.

Route d'Arles

Route d'Arles might not have many top sights, but Nimes Arena and Nemausus are two attractions nearby that you can check out.

Top Santa Cruz Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Cruz like?
Guests are sure to enjoy their time checking out all that Nîmes's Santa Cruz neighbourhood has to offer.
How many hotels will I find in the Santa Cruz area?
Expedia has 9 Santa Cruz hotels and other accommodation options, and one might make a good home base for venturing out into the greater Nîmes area.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the top deals on offer in Santa Cruz.
What is there to do in this Nîmes neighbourhood?
Nîmes Museum of Natural History and Prehistory, Herbes Square and Old Nimes Museum are just a few of the places to visit in and around Santa Cruz. While you're out sightseeing, Les Halles de Nîmes and Nîmes Clock Tower are a couple of additional sights to visit in Nîmes.