Search Hotels in Santa Cruz, Orlando

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Holiday Inn Express & Suites Clermont Se West Orlando by IHG

Holiday Inn Express & Suites Clermont Se West Orlando by IHG
2.5 star property
9.1 km from Santa Cruz
8.4 out of 10, Very good, (1061)
"Great room great breakfast"
United States
Kelly
The price is 2.899.270 ₫
3.218.189 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Clermont Se West Orlando by IHG

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando

Sheraton Vistana Villages Resort Villas, I-Drive/Orlando
4.0 star property
22.2 km from Santa Cruz
9.2 out of 10, Wonderful, (2724)
"Stayed here before always enjoyed it "
United States
Margaret
The price is 2.530.272 ₫
2.846.555 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Sheraton Vistana Villages Resort Villas, I-Drive/Orlando

Summer Bay Orlando by Exploria Resorts

Summer Bay Orlando by Exploria Resorts
3.5 star property
8.9 km from Santa Cruz
8.8 out of 10, Excellent, (2073)
"Enjoyed the friendly bartenders and staff. "
United States
Todd J
The price is 3.005.837 ₫
4.214.600 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Summer Bay Orlando by Exploria Resorts

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
4.0 star property
18.8 km from Santa Cruz
9.4 out of 10, Exceptional, (4072)
"Beautiful resort"
United States
Antonese
The price is 2.930.898 ₫
3.297.260 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

The Grove Resort & Water Park Orlando

The Grove Resort & Water Park Orlando
4.0 star property
10.4 km from Santa Cruz
8.0 out of 10, Very good, (8797)
"It was a great place to stay."
United States
Katherine Mercedes Cruz
The price is 3.927.193 ₫
5.871.022 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Grove Resort & Water Park Orlando

SPOT X Hotel Orlando/Intl Dr by The Red Collection

SPOT X Hotel Orlando/Intl Dr by The Red Collection
3.0 star property
21.6 km from Santa Cruz
8.6 out of 10, Excellent, (2944)
"Clean room, close to Disney and good breakfast at a reasonable price"
United States
pamela
The price is 1.992.589 ₫
2.715.823 ₫ total
includes taxes & fees
14 Dec - 15 Dec
SPOT X Hotel Orlando/Intl Dr by The Red Collection

Kompose Boutique Resort at Theme Parks

Kompose Boutique Resort at Theme Parks
3.0 star property
10.3 km from Santa Cruz
9.4 out of 10, Exceptional, (1950)
"Beautiful resort with very friendly staff. "
United States
kristie
The price is 1.609.358 ₫
2.873.176 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Kompose Boutique Resort at Theme Parks

Aloft Orlando Lake Buena Vista

Aloft Orlando Lake Buena Vista
3.0 star property
21.3 km from Santa Cruz
8.8 out of 10, Excellent, (1906)
"Great rooms, staff, and property!"
United States
Cindy
The price is 1.950.418 ₫
2.194.220 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Aloft Orlando Lake Buena Vista

Westgate Lakes Resort & Spa Universal Studios Area

Westgate Lakes Resort & Spa Universal Studios Area
4.0 star property
25.5 km from Santa Cruz
8.2 out of 10, Very good, (5561)
"Clean room and staff was awesome "
United States
Shawanda
The price is 2.574.552 ₫
3.785.656 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Westgate Lakes Resort & Spa Universal Studios Area

Avanti International Resort

Avanti International Resort
4.0 star property
26.5 km from Santa Cruz
7.8 out of 10, Good, (4293)
"Enjoyed our stay "
United States
Sheltra
The price is 1.828.061 ₫
2.590.298 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Avanti International Resort

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
28.2 km from Santa Cruz
9.4 out of 10, Exceptional, (4344)
"Great resort "
United States
Camille
The price is 2.930.898 ₫
3.297.260 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Rosen Shingle Creek

Seasons Florida Resort

Seasons Florida Resort
2.0 star property
19.4 km from Santa Cruz
8.8 out of 10, Excellent, (3282)
"Excellent location and value, very clean and friendly check in"
United States
Jason
The price is 1.601.188 ₫
1.817.348 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Seasons Florida Resort

Hampton Inn & Suites Orlando Intl Dr N

Hampton Inn & Suites Orlando Intl Dr N
2.5 star property
27.5 km from Santa Cruz
9.2 out of 10, Wonderful, (1074)
"Second time staying at this hotel and loved it great hotel for family and close to the main attractions "
United States
Kadeisha
The price is 2.357.214 ₫
2.651.865 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Orlando Intl Dr N

Caribe Royale Orlando

Caribe Royale Orlando
4.5 star property
19.2 km from Santa Cruz
9.2 out of 10, Wonderful, (4503)
"Clean and very friendly staff"
United States
Nafeeza
The price is 4.190.763 ₫
5.841.502 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Caribe Royale Orlando

Holiday Inn Express & Suites Orlando - Lake Buena Vista by IHG

Holiday Inn Express & Suites Orlando - Lake Buena Vista by IHG
3.0 star property
21.4 km from Santa Cruz
8.8 out of 10, Excellent, (2249)
"Waa a really wonderful place to stay was clean and comfortable and nice breakfast."
United States
Brenda
The price is 2.187.631 ₫
2.461.084 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express & Suites Orlando - Lake Buena Vista by IHG

Hyatt Regency Grand Cypress

Hyatt Regency Grand Cypress
4.0 star property
19.8 km from Santa Cruz
9.2 out of 10, Wonderful, (2281)
"The staff was attentive and we really enjoyed the amenities! "
United States
Michelle
The price is 4.246.113 ₫
6.259.459 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hyatt Regency Grand Cypress

Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG

Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG
3.0 star property
21.8 km from Santa Cruz
9.0 out of 10, Wonderful, (1652)
"Excelente hotel"
Mexico
Aroldo
The price is 2.530.272 ₫
2.846.556 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG

Pestana Orlando Suites - Lake Buena Vista

Pestana Orlando Suites - Lake Buena Vista
4.0 star property
21 km from Santa Cruz
9.4 out of 10, Exceptional, (1970)
"Staff was nice, rooms were spacious and very clean. We loved the location, very close to Disney Springs and Universal at the same time."
United States
LILLIANA
The price is 2.030.490 ₫
2.581.096 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Pestana Orlando Suites - Lake Buena Vista

Wyndham Grand Orlando Resort Bonnet Creek

Wyndham Grand Orlando Resort Bonnet Creek
4.0 star property
15.7 km from Santa Cruz
8.8 out of 10, Excellent, (2815)
"Great hotel"
United States
Hai
The price is 3.689.980 ₫
5.396.595 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Wyndham Grand Orlando Resort Bonnet Creek

Rosen Inn International

Rosen Inn International
3.0 star property
27.5 km from Santa Cruz
8.4 out of 10, Very good, (5892)
"Excellent hotel. Will stay here every time I come back to Bogota"
United States
Daniel
The price is 2.108.296 ₫
2.371.866 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Rosen Inn International
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Cruz

Find the best Santa Cruz areas for the activities you enjoy most.

International Drive District

Visitors to International Drive District rave about its breathtaking beach views, exciting theme parks and popular shops. You might also want to make some time to see Pointe Orlando or Aquatica while you're exploring the neighbourhood.

Bay Lake

Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.

Champions Gate

Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Florida Center

If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.

Downtown Orlando

Ample dining options, great live music, and fantastic lake views are just a few top things to explore in Downtown Orlando. A visit to The Social or Orlando City Hall might round out your trip, and you can jump aboard the metro at Church Street Station or Lynx Central Station to get around town.

Top Santa Cruz Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Cruz like?
Travellers to the Santa Cruz neighbourhood in Four Corners will be sure to enjoy their stay.
How many hotels will I be able to find in Santa Cruz?
With 13 Expedia hotels and other accommodation options in Santa Cruz to choose from, this is a good starting point for exploring the greater Four Corners area.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best deals available in Santa Cruz.
What can I see and do in this Four Corners neighbourhood?
A few places to visit in the area around Santa Cruz include ChampionsGate Golf Club, Highland Reserve Golf Club and Posner Village. When you're sightseeing around the area, Northeast Regional Park and Reunion Resort Golf Course are a couple of other sights to visit.