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Check availability on Santa Cruz Boutique Hotels

Tonight
21 Dec - 22 Dec
Tomorrow
22 Dec - 23 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Our top choices for Santa Cruz boutique hotels

Seasonal outdoor pool
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
Historical Center
9.2 out of 10, Wonderful, (1001)
"The property had real historic character - in a great location with helpful and friendly staff "
United Kingdom
Caroline Jane
The price is 3.182.423 ₫
3.500.665 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Las Casas de la Judería, Sevilla Historic City Center
Lobby sitting area
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
Historical Center
9.6 out of 10, Exceptional, (1089)
"A great spot with a wonderful staff and breakfast"
Canada
Don
The price is 3.428.737 ₫
3.771.611 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Amadeus Sevilla
Courtyard
El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Historical Center
9.4 out of 10, Exceptional, (893)
"The location is A+! The staff is extremely attentive and knowledgeable their rooms where pristine and comfortable. The bed is very good. Breakfast is amazing. This hotel delivers a great experience."
United States
WALDECTOR
The price is 4.260.812 ₫
4.686.893 ₫ total
includes taxes & fees
21 Dec - 22 Dec
El Rey Moro Hotel Boutique
Porch
Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello
4.0 star property
Historical Center
9.4 out of 10, Exceptional, (684)
"The hotel is centric"
United States
javier
The price is 3.071.577 ₫
3.378.735 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Boutique Palacio Pinello
Spa
Eurostars Sevilla Boutique

Eurostars Sevilla Boutique

Eurostars Sevilla Boutique
4.0 star property
Historical Center
9.0 out of 10, Wonderful, (490)
"Room was spotless, staff was courteous and location was perfect!"
United States
Andrean
The price is 2.801.144 ₫
3.081.258 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Eurostars Sevilla Boutique
Grand Room, Terrace (Pool) | Premium bedding, down duvets, in-room safe, individually decorated
Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection
3.0 star property
Historical Center
9.6 out of 10, Exceptional, (95)
"Staff was extremely helpful and always very pleasant."
United States
Gregory Carroll
The price is 6.470.879 ₫
7.117.967 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Boutique Corral del Rey by ALUZ Collection
Interior entrance
Hotel Casa de Colón

Hotel Casa de Colón

Hotel Casa de Colón
3.0 star property
Historical Center
9.0 out of 10, Wonderful, (330)
"What a beautiful hotel right in the heart of Seville. My room was spotless , the bed so comfortable and the staff were so friendly and helpful. I had breakfast on the terrace and in the lobby …both were delicious. A wonderful place to stay "
United Kingdom
Sue
The price is 2.323.054 ₫
2.555.390 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Casa de Colón
Outdoor pool, pool umbrellas
Halo Boutique Hotel

Halo Boutique Hotel

Halo Boutique Hotel
4.0 star property
Historical Center
9.2 out of 10, Wonderful, (448)
"Lovely staff, perfect location for the sights of seville"
United Kingdom
Karl
Halo Boutique Hotel
Seasonal outdoor pool
Hotel Doña Maria

Hotel Doña Maria

Hotel Doña Maria
4.0 star property
Historical Center
9.0 out of 10, Wonderful, (1001)
"The hotel has the best location, and the staff is very friendly and helpful."
United States
Waleska
The price is 2.941.487 ₫
3.235.759 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Hotel Doña Maria
City view from property
EME Catedral Mercer Hotel

EME Catedral Mercer Hotel

EME Catedral Mercer Hotel
5.0 star property
Historical Center
8.8 out of 10, Excellent, (1000)
"A great hotel in a fabulous location. We thoroughly enjoyed our stay. Most of the staff were excellent and very helpful and friendly. A small criticism would be on the breakfast, which is quite moderate in terms of range and quality. But we would certainly stay here again. "
United Kingdom
Leo Roderick
The price is 5.042.261 ₫
5.546.487 ₫ total
includes taxes & fees
21 Dec - 22 Dec
EME Catedral Mercer Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Frequently asked questions

Searching for a cosy accommodation option when you visit Santa Cruz?
A boutique hotel may be just what you want if you enjoy smaller hotels with quality service and a cool atmosphere. Select from 17 boutique-style accommodation options in Santa Cruz to find a property that characterises the local flavour of this destination.
How many boutique hotels should I expect to find in Santa Cruz?
Expedia has 17 boutique hotels in Santa Cruz.
What's there to see and do in Santa Cruz?
Visitors speak positively about this destination's fantastic nightlife, cultural attractions and stunning cathedral. Activities and attractions to experience around Santa Cruz include Convent of the Incarnation, Giralda Tower and General Archive of the Indies. While you're here, you might also like to explore more of the area and take in additional sights like Archbishop's Palace, Triunfo Plaza and Puerta del Príncipe.
What's the best way to get to my boutique hotel in Santa Cruz?
You have a few options for travelling to and around Santa Cruz. The closest major airport is Seville (SVQ-San Pablo), which is located 5.7 mi (9.1 km) away. Make your way to Puerta Jerez Tram Stop for metro travel.