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Check availability on Santa Cruz Hotels Suites

Our top choices for Santa Cruz hotels with suites

Lobby sitting area
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

Hotel Amadeus Sevilla
4.0 star property
Historical Center
9.6 out of 10, Exceptional, (1079)
"A great spot with a wonderful staff and breakfast"
Canada
Don
The price is 3.411.932 ₫
3.753.125 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Amadeus Sevilla
Suite (Balcón Rosina) | Living area
Suites Murillo Plaza Sta Cruz

Suites Murillo Plaza Sta Cruz

Suites Murillo Plaza Sta Cruz
3.5 star property
Historical Center
9.8 out of 10, Exceptional, (215)
"I love this hotel, it’s accessible to everywhere."
Canada
WENZHE
Suites Murillo Plaza Sta Cruz
Seasonal outdoor pool, open noon to 9 PM, pool umbrellas, pool loungers
Hotel Fernando III

Hotel Fernando III

Hotel Fernando III
4.0 star property
Historical Center
9.6 out of 10, Exceptional, (1534)
"Great location & staff were wonderful!"
United States
Fawn
The price is 16.037.491 ₫
17.641.240 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hotel Fernando III
Porch
Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello

Hotel Boutique Palacio Pinello
4.0 star property
Historical Center
9.4 out of 10, Exceptional, (681)
"The hotel is centric"
United States
javier
The price is 2.597.681 ₫
2.857.449 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Boutique Palacio Pinello
City view from property
Pensión dulces sueños

Pensión dulces sueños

Pensión dulces sueños
1.0 star property
Historical Center
9.0 out of 10, Wonderful, (52)
"Clean room, location close to the historical landmarks and good eating places close by. Amenities such as a terrace available."
Canada
Hubert
The price is 1.279.474 ₫
1.407.421 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Pensión dulces sueños
Exclusive Duplex, 1 Bedroom, Private Pool | Terrace/patio
Welldone Cathedral

Welldone Cathedral

Welldone Cathedral
3.5 star property
Historical Center
9.0 out of 10, Wonderful, (322)
"Great location, clean room, safe and quiet. "
United States
Yolanda
The price is 3.010.114 ₫
3.311.125 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Welldone Cathedral
Terrace/patio
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
Historical Center
9.2 out of 10, Wonderful, (1004)
"The property had real historic character - in a great location with helpful and friendly staff "
United Kingdom
Caroline Jane
The price is 3.177.859 ₫
3.495.645 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Las Casas de la Judería, Sevilla Historic City Center
Courtyard
El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Historical Center
9.4 out of 10, Exceptional, (891)
"The location is A+! The staff is extremely attentive and knowledgeable their rooms where pristine and comfortable. The bed is very good. Breakfast is amazing. This hotel delivers a great experience."
United States
WALDECTOR
The price is 2.727.916 ₫
3.000.862 ₫ total
includes taxes & fees
17 Dec - 18 Dec
El Rey Moro Hotel Boutique
Lobby
Hotel Alcántara

Hotel Alcántara

Hotel Alcántara
2.0 star property
Historical Center
9.0 out of 10, Wonderful, (826)
"24 hour front desk is very helpful; very good location close to major attractions while still quiet; very friendly staff."
Canada
WEN LI
The price is 1.654.217 ₫
1.819.639 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Hotel Alcántara
View from property
Hotel Murillo

Hotel Murillo

Hotel Murillo
2.0 star property
Historical Center
8.8 out of 10, Excellent, (1003)
"Staff was very friendly, perfect location can’t get any better than this hotel"
United States
Aldon
Hotel Murillo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

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Expedia's handy filters will help you find a cheap hotel with suites in Santa Cruz. First, set your per-night budget. Next, choose your preferred hotel star rating — properties with lower ratings are more affordable. You can also search for accommodation in less popular neighbourhoods or ones that are further away from the centre. Another tip? Keep an eye out for last-minute deals!