Search Hotels with Air Conditioning in Santa Cruz

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Cruz Hotels with Air Conditioning

Our top choices for Santa Cruz hotels with air conditioning

Panoramic Penthouse, Terrace, City View (Pool) | Premium bedding, down duvets, in-room safe, individually decorated
Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection

Hotel Boutique Corral del Rey by ALUZ Collection
3.0 star property
Historical Center
9.6 out of 10, Exceptional, (94)
"Would highly recommend, staff excellent, beautiful hotel"
United Kingdom
Neil
The price is 5.630.488 ₫
6.193.537 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hotel Boutique Corral del Rey by ALUZ Collection
Courtyard
Genteel Home Palacio Abades Terrace

Genteel Home Palacio Abades Terrace

Genteel Home Palacio Abades Terrace
3.0 star property
Historical Center
10.0 out of 10, Exceptional, (2)
"Great place to stay! Also they were very helpful with helping to plan an itinerary of things to do in Seville as well as booking restaurants and activities for us, which was a very nice touch."
United Kingdom
Simon
The price is 14.517.014 ₫
17.265.593 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Genteel Home Palacio Abades Terrace
Deluxe Apartment, 1 Bedroom | Terrace/patio
Suites Murillo Alcazar

Suites Murillo Alcazar

Suites Murillo Alcazar
3.5 star property
Historical Center
9.6 out of 10, Exceptional, (89)
"Wonderful location, spacious accommodations, friendly staff"
United States
William
Suites Murillo Alcazar
Rooftop terrace
Numa Seville Prestigio

Numa Seville Prestigio

Numa Seville Prestigio
3.5 star property
Historical Center
9.8 out of 10, Exceptional, (9)
"Great location. Very central and many dining options nearby. "
United States
Dev
The price is 5.439.289 ₫
5.983.218 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Numa Seville Prestigio
Outdoor pool, pool umbrellas, pool loungers
Los Seises Sevilla, a Tribute Portfolio Hotel

Los Seises Sevilla, a Tribute Portfolio Hotel

Los Seises Sevilla, a Tribute Portfolio Hotel
4.0 star property
Historical Center
8.4 out of 10, Very good, (501)
"Get location and beautiful hotel "
United States
Leandro
The price is 4.487.918 ₫
4.936.710 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Los Seises Sevilla, a Tribute Portfolio Hotel
Courtyard
El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique

El Rey Moro Hotel Boutique
4.0 star property
Historical Center
9.4 out of 10, Exceptional, (891)
"The location is A+! The staff is extremely attentive and knowledgeable their rooms where pristine and comfortable. The bed is very good. Breakfast is amazing. This hotel delivers a great experience."
United States
WALDECTOR
The price is 2.712.124 ₫
2.983.490 ₫ total
includes taxes & fees
17 Dec - 18 Dec
El Rey Moro Hotel Boutique
Yoga
MDD4 Health Experience Hotel Sevilla - Adults Only

MDD4 Health Experience Hotel Sevilla - Adults Only

MDD4 Health Experience Hotel Sevilla - Adults Only
2.0 star property
Historical Center
9.4 out of 10, Exceptional, (39)
"Wonderful place that is close to all major attractions. Rooms are decorated impeccably and offer everything."
United States
Julissa
The price is 1.334.891 ₫
1.468.380 ₫ total
includes taxes & fees
15 Dec - 16 Dec
MDD4 Health Experience Hotel Sevilla - Adults Only
Snack bar
Casa del Contratador by Época Suites

Casa del Contratador by Época Suites

Casa del Contratador by Época Suites
Historical Center
8.0 out of 10, Very good, (1)
"Todo excelente, únicamente la llegada no estaba lista la habitación a la hora del checkin"
Mexico
EMILIO
Casa del Contratador by Época Suites
Exterior
Casa Palacio La Casa Blanca Suites

Casa Palacio La Casa Blanca Suites

Casa Palacio La Casa Blanca Suites
3.0 star property
Historical Center
9.6 out of 10, Exceptional, (354)
"Amazing place in a perfect location! "
Canada
Olga
The price is 5.450.504 ₫
5.995.554 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Casa Palacio La Casa Blanca Suites
Interior
Suites Machado

Suites Machado

Suites Machado
3.5 star property
Historical Center
9.8 out of 10, Exceptional, (115)
"Looked just like the pictures. Surrounded by good restaurants. Easy to walk to land marks. The receptionists are helpful as well. "
United States
Jun Hyung
The price is 2.101.413 ₫
2.311.554 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Suites Machado
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Cruz Hotel Reviews

Explore a world of travel with Expedia