Santa Maria Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most. Learn more about Santa Maria
Fachada colorida de estilo colonial, barrio de Santa Ana, Guayaquil, Ecuador

Ecuador

Ecuador might not have many top sights, but C.C. Riocentro Sur and Mall del Sur are two attractions nearby that you can check out.

Find hotels in Ecuador

Top hotels in Santa Maria

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Fully refundable
The price is 2.413.257 ₫ per night from 28 Feb to 1 Mar
2.413.257 ₫
2.719.455 ₫ total
28 Feb - 1 Mar
9.2/10 Wonderful! (1,003 reviews)
Clean walking distance from airport. Great staff, good food

Reviewed on 28 Jan 2026

Holiday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is 2.592.305 ₫ per night from 17 Feb to 18 Feb
2.592.305 ₫
2.916.409 ₫ total
17 Feb - 18 Feb
9.2/10 Wonderful! (1,000 reviews)
Excelente localidad y excelente servicio

Reviewed on 29 Jan 2026

Wyndham Guayaquil Puerto Santa Ana
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Fully refundableReserve now, pay when you stay
The price is 2.075.920 ₫ per night from 1 Feb to 2 Feb
2.075.920 ₫
2.348.385 ₫ total
1 Feb - 2 Feb
9.4/10 Exceptional! (1,001 reviews)
Upgrade was excellent as wss the complimentary airport transfers.

Reviewed on 25 Jan 2026

Oro Verde Guayaquil
See all 424 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Maria holiday package cost?
Get set to book, because a getaway to Santa Maria starts from a tempting . When you combine your hotels, flights and car rentals into a travel package, you'll enjoy the lowest prices.
How do I get a cheap travel package to Santa Maria?
Bundle your hotels and flights with Expedia to save big on your next trip. With more than 550 air carriers and 1null000null000 hotels worldwide, your Santa Maria holiday package can be customized exactly to suit your travel style. With all that extra cash, why not add a few fun activities and tours? It's an easy way to unlock even more savings. Your dream holiday in Santa Maria is closer than you thought!
Where should I stay in Santa Maria?
Make sightseeing easy by staying someplace right around the corner from Santa Maria's biggest attractions. Malecon 2000 and Banco Pichincha Monumental Stadium are two visitor favourites.
How far in advance should I book my Santa Maria holiday?
Your safest bet is to book early. Airlines usually release flight tickets nearly 12 months prior to departure, and this is a great opportunity to score some rock-bottom prices. Just been told you should take your holiday time next month? No sweat. Expedia are never short on fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Maria travel package include?
Select from any combination of flights, hotels and rental cars. Once you've made your booking, you can add activities and experiences. Want to pick your airfare class? That's easy to do too. The choice is all yours when it comes to arranging your dream Santa Maria escape.
What should I know before booking a Santa Maria travel package?
Get set to save with an Expedia travel package. Combine your flights, rental cars and hotels and enjoy exciting discounts. Hotels aren't your only choice, however. Book with us and choose from beach villas, creek-side mountain cabins and just about everything in between!
Can I choose my airline with a Santa Maria Expedia holiday package?
Expedia offers access to more than 550 airline partners globally, so you certainly can. Just pick your preferred air carrier and put together your ideal Santa Maria escape.
If I'm not able to travel, can I cancel my Santa Maria holiday package?
Yes, you can cancel your Santa Maria booking if your travel plans have been upended. Whether you'll incur a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change your booking for free if you booked in the last 24 hours. Head to our Customer Service Portal to learn more.

Popular places to visit

By the riverside

Malecon 2000

Malecon 2000 is just one of the places to see in Guayaquil, so why not enjoy the other things to explore during your travels? While you're in the area, find time to visit its shops.

Malecon 2000
The river front of Guayaquil

City Mall

During your visit to Guayaquil, you can do some window-shopping at City Mall. Visit the area's cathedral or simply enjoy its seafood restaurants.

City Mall
Seaside Malecon 2000 walkway with Santa Ana Hill, Ecuador

Santa Ana Hill

Explore the great outdoors at Santa Ana Hill, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.

Santa Ana Hill