Find hotels in Santee, SC from 1.492.147 ₫

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Tonight
4 Jul - 5 Jul
Tomorrow
5 Jul - 6 Jul
This weekend
4 Jul - 6 Jul
Next weekend
11 Jul - 13 Jul

Filter by

Guest rating
Guest rating
Property class

Top 10 Santee hotels and places to stay

Hampton Inn Santee-I-95
Seasonal outdoor pool

Hampton Inn Santee-I-95

2.5 star property
9.6 out of 10, Exceptional, (1004)
"Great overnight visit!!!!"
The price is 3.529.013 ₫
3.917.206 ₫ total
includes taxes & fees
4 Aug - 5 Aug
Hampton Inn Santee-I-95
Fairfield Inn & Suites by Marriott Santee
Property amenity

Fairfield Inn & Suites by Marriott Santee

2.5 star property
9.8 out of 10, Exceptional, (1002)
"Great stay!"
The price is 3.406.130 ₫
3.780.805 ₫ total
includes taxes & fees
10 Jul - 11 Jul
Fairfield Inn & Suites by Marriott Santee
Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | 1 bedroom, free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.2 out of 10, Wonderful, (464)
"This hotel was so conveniently located. Right off the interstate and was quiet. Would stay again if in the area."
The price is 2.646.301 ₫
2.937.394 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Tru By Hilton Santee
Best Western Plus Santee Inn
Exterior

Best Western Plus Santee Inn

2.5 star property
8.8 out of 10, Excellent, (1002)
"Nice stay for overnight. Great pool!"
The price is 3.006.565 ₫
3.337.286 ₫ total
includes taxes & fees
16 Jul - 17 Jul
Best Western Plus Santee Inn
Holiday Inn Santee by IHG
Exterior

Holiday Inn Santee by IHG

3.0 star property
8.2 out of 10, Very good, (904)
"Very clean, comfy beds, just what we needed after a long day on the road!"
The price is 3.641.939 ₫
4.042.552 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Holiday Inn Santee by IHG
Baymont by Wyndham Santee
Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi

Baymont by Wyndham Santee

2.5 star property
8.0 out of 10, Very good, (1313)
"Nice place to stay overnight ... friendly staff. "
The price is 1.964.813 ₫
2.180.942 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Baymont by Wyndham Santee
Comfort Inn & Suites Santee
Lobby

Comfort Inn & Suites Santee

2.5 star property
8.0 out of 10, Very good, (1001)
"My kids highly enjoyed the cookies, the staff was always pleasant and friendly, and honestly I highly recommend staying here. We will most definitely stay again. "
The price is 2.965.429 ₫
3.291.626 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Comfort Inn & Suites Santee
Travelodge by Wyndham Santee
Exterior

Travelodge by Wyndham Santee

2.0 star property
7.0 out of 10, Good, (638)
"Very nice anf clean"
The price is 1.624.462 ₫
1.803.151 ₫ total
includes taxes & fees
7 Jul - 8 Jul
Travelodge by Wyndham Santee
Super 8 by Wyndham Santee
Lobby

Super 8 by Wyndham Santee

2.0 star property
6.8 out of 10, (426)
"Resturants and stores close by"
The price is 1.965.075 ₫
2.181.233 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Super 8 by Wyndham Santee
Red Roof Inn Santee
Exterior

Red Roof Inn Santee

2.0 star property
6.6 out of 10, (617)
"it was clean and the staff was friendly"
The price is 1.676.864 ₫
1.861.319 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Red Roof Inn Santee
Econo Lodge
Exterior

Econo Lodge

2.0 star property
6.4 out of 10, (308)
"Check in was easy."
The price is 1.554.505 ₫
1.725.501 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Econo Lodge
Ramada by Wyndham Santee I-95
Property amenity

Ramada by Wyndham Santee I-95

2.0 star property
6.2 out of 10, (525)
"There was no one at the front desk and my daughter called the number and no one answered. I tried to call as well. I would like a full refund since she had to go to another hotel. "
The price is 2.182.543 ₫
2.422.806 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Ramada by Wyndham Santee I-95
Quality Inn & Suites
Business centre

Quality Inn & Suites

2.5 star property
6.0 out of 10, (398)
"Clean n great owners "
The price is 1.648.043 ₫
1.974.482 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Quality Inn & Suites
SureStay Hotel by Best Western Manning
BBQ/picnic Area

SureStay Hotel by Best Western Manning

2.5 star property
8.6 out of 10, Excellent, (1000)
"Staff was very friendly and helpful, definitely recommend staying here"
The price is 2.986.914 ₫
3.315.475 ₫ total
includes taxes & fees
8 Jul - 9 Jul
SureStay Hotel by Best Western Manning
Holiday Inn Express & Suites Orangeburg by IHG
Exterior

Holiday Inn Express & Suites Orangeburg by IHG

2.5 star property
8.6 out of 10, Excellent, (755)
"Very nice clean hotel with comfortable beds."
The price is 3.170.321 ₫
3.519.055 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Holiday Inn Express & Suites Orangeburg by IHG
Bells Marina & Resort
Lake

Bells Marina & Resort

2.5 star property
8.6 out of 10, Excellent, (68)
"Would stay again"
Bells Marina & Resort
Fairfield Inn by Marriott Orangeburg
Reception

Fairfield Inn by Marriott Orangeburg

2.5 star property
8.4 out of 10, Very good, (616)
"Convenient to the main road between Columbia and Charleston SC. RT 26"
The price is 2.436.693 ₫
2.704.729 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Fairfield Inn by Marriott Orangeburg
Hampton Inn Manning
Interior entrance

Hampton Inn Manning

2.5 star property
8.4 out of 10, Very good, (939)
"Great service and nice place to stay."
The price is 3.155.386 ₫
3.502.480 ₫ total
includes taxes & fees
14 Jul - 15 Jul
Hampton Inn Manning
SpringHill Suites by Marriott Orangeburg
Free WiFi, bed sheets

SpringHill Suites by Marriott Orangeburg

2.5 star property
9.0 out of 10, Wonderful, (609)
"The stay was very nice and convenient. The staff was nice and friendly. Only issue was the cleaning lady misplaced her phone and used her key to unlock our room without knocking, then proceeded to walk in until we stopped her."
The price is 3.379.929 ₫
3.751.722 ₫ total
includes taxes & fees
6 Jul - 7 Jul
SpringHill Suites by Marriott Orangeburg
Tru by Hilton Orangeburg
Reception

Tru by Hilton Orangeburg

2.5 star property
9.2 out of 10, Wonderful, (1002)
"Friendly staff and great room"
The price is 3.151.456 ₫
3.498.117 ₫ total
includes taxes & fees
4 Aug - 5 Aug
Tru by Hilton Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Pet-friendly hotels in Santee you'll enjoy

Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | 1 bedroom, free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.2 out of 10, Wonderful, (464)
The price is 2.646.301 ₫
2.937.394 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Tru By Hilton Santee

These apart-hotels in Santee may fit your trip

Bells Marina & Resort
Lake

Bells Marina & Resort

2.5 star property
8.6 out of 10, Excellent, (68)
Bells Marina & Resort

Check out hotels with a pool in Santee

Tru By Hilton Santee
Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing) | 1 bedroom, free WiFi, bed sheets

Tru By Hilton Santee

2.5 star property
9.2 out of 10, Wonderful, (464)
The price is 2.646.301 ₫
2.937.394 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Tru By Hilton Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santee

Love dining, golf and lake views? Get away to Santee!

See all hotels in Santee

Frequently asked questions

What's the seasonal weather like in Santee?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.