Find hotels in Santee, SC from 1.654.825 ₫

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santee hotels

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,003 reviews)
"Convenient location & clean with very nice staff"
United States
Michael
The price is 3.528.573 ₫
3.916.717 ₫ total
includes taxes & fees
14 Jun - 15 Jun
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,002 reviews)
"Great stay!"
United States
Preston
The price is 3.376.747 ₫
3.748.190 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Hampton Inn Santee-I-95

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,468 reviews)
"Great overnight stop"
United States
Gary
The price is 2.104.777 ₫
2.336.303 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Baymont by Wyndham Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (842 reviews)
"The older man that worked upfront at the time of my check in was super nice and helpful!"
United States
Kristal
The price is 2.868.380 ₫
3.183.902 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Tru By Hilton Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,002 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
United States
Nicole
The price is 3.108.881 ₫
3.450.857 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Best Western Plus Santee Inn

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (733 reviews)
"Staff was very friendly. "
United States
Sriram
The price is 1.657.719 ₫
1.840.069 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Travelodge by Wyndham Santee

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (465 reviews)
"Ok hotel when money is tight. Only stayed one night but the room was clean and the beds were pretty comfy."
United States
Christalyn
The price is 1.677.454 ₫
1.861.975 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Super 8 by Wyndham Santee/I-95

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,007 reviews)
"This property is right off the interstate with no traffic. The staff was very friendly and the hotel was clean. Breakfast and coffee were delicious. Highly recommend "
United States
Kimberley
The price is 2.729.711 ₫
3.029.942 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Comfort Inn & Suites Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (536 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
The price is 1.431.427 ₫
1.734.658 ₫ total
includes taxes & fees
23 Jun - 24 Jun
Quality Inn & Suites Santee I-95

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (655 reviews)
"Yes, great room."
United States
Gerald
The price is 1.657.482 ₫
1.839.805 ₫ total
includes taxes & fees
7 Jun - 8 Jun
Red Roof Inn Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,001 reviews)
"Room was super clean and nice. Convenient location off of 95 and near Santee state park. Only minor complaint is the pool wasn't heated as stated. "
United States
Stefanie
The price is 2.683.926 ₫
2.979.158 ₫ total
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Santee by IHG

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (562 reviews)
"Clean room and good staff"
United States
Herbert
The price is 1.941.899 ₫
2.155.508 ₫ total
includes taxes & fees
8 Jun - 9 Jun
Ramada by Wyndham Santee I-95

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (314 reviews)
"Very clean room, fast staff, a lot of food spots nearby! "
United States
Santiana
The price is 1.776.917 ₫
1.972.378 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Econo Lodge Santee

Sunset Inn Manning I 95

Sunset Inn Manning I 95
2.0 star property
Summerton
4.8 out of 10, (55 reviews)
"Ok good value"
United States
William
The price is 1.334.069 ₫
1.480.817 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Sunset Inn Manning I 95

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.2 out of 10, Good, (217 reviews)
"Was very clean and confortable "
United States
David
The price is 1.565.887 ₫
1.691.400 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Peach Tree Inn

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (781 reviews)
"Great stay!!"
United States
Laylany
The price is 2.885.220 ₫
3.202.595 ₫ total
includes taxes & fees
3 Jun - 4 Jun
Fairfield Inn by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (760 reviews)
"Clean and safe. The breakfast choices are plentiful and the coffee was good. "
United States
Valerie
The price is 2.987.052 ₫
3.315.627 ₫ total
includes taxes & fees
21 Jun - 22 Jun
SpringHill Suites by Marriott Orangeburg

Southern Lodge 601

Southern Lodge 601
Orangeburg
7.6 out of 10, Good, (10 reviews)
"The front desk and housekeeping staff were friendly and accommodating. The room was clean and comfortable but had a little "stale" odor but I became accustomed to it quickly. I felt safe in my room, and the neighbors were very quiet. Will stay here again, great bargain and convenient to I-26!"
United States
Stephanie
The price is 1.598.514 ₫
1.774.351 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Southern Lodge 601

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (803 reviews)
"Helpful, friendly staff. Good location"
United States
Toy
The price is 3.439.372 ₫
3.817.703 ₫ total
includes taxes & fees
2 Jul - 3 Jul
Hampton Inn & Suites Orangeburg

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very good, (1,003 reviews)
"Wonderful stay!"
United States
Joie
The price is 2.078.727 ₫
2.307.387 ₫ total
includes taxes & fees
2 Jun - 3 Jun
Travelodge by Wyndham Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap stays in Santee

Hotels in Santee with star rating

Frequently asked questions

What's the seasonal weather like in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.