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Check availability on Santissima Annunziata Spa Hotels

Our top choices for Santissima Annunziata hotels with a spa

Forte16 View & Spa

Forte16 View & Spa
Santissima Annunziata
9.6 out of 10, Exceptional, (897)
"The room was great, balcony was magnificent and not too far from the major attractions. The front desk was helpful and accommodating. "
United States
Sean
The price is 2.979.160 ₫
3.648.066 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Forte16 View & Spa

Four Seasons Hotel Firenze

Four Seasons Hotel Firenze
5.0 star property
Historic Centre of Florence
9.8 out of 10, Exceptional, (287)
"Five star resort. Staff is incredible "
United States
Scott
The price is 24.423.494 ₫
27.360.496 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Four Seasons Hotel Firenze

My Forte Relais de Charme

My Forte Relais de Charme
Santissima Annunziata
9.0 out of 10, Wonderful, (78)
"Clean rooms, great amenities "
United States
Yevgenya
The price is 4.473.250 ₫
5.291.938 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
My Forte Relais de Charme

Casaldo's rooms

Casaldo's rooms
Santissima Annunziata
The price is 3.794.298 ₫
4.544.718 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Casaldo's rooms

Villa Cora

Villa Cora
5.0 star property
Oltrarno
9.8 out of 10, Exceptional, (468)
"Nice property and staff."
United States
Hugo
Villa Cora

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Historic Centre of Florence
10.0 out of 10, Exceptional, (24)
"This boutique was an absolute must stay. From the location to the comfort of our room and the lovely staff, it was all you could ask for during a stay in Florence. The walkability was incredible, and even though there is a lively crowd nightly outside of the building, your room is peaceful. Highly recommend this hotel to anyone looking for a unique stay in Florence! "
United States
Chris
The price is 4.198.930 ₫
4.989.813 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
SPIRIT OF FLORENCE Boutique Rooms

COMO Castello Del Nero

COMO Castello Del Nero
5.0 star property
Barberino Tavarnelle
9.6 out of 10, Exceptional, (133)
"Wonderful stay. 5-stars across the board if you’re looking for disconnecting and relaxing in the rolling hills of the Tuscan countryside. Easy day/dinner trips to Florence or Siena (rental car). "
United States
Matthew
The price is 22.026.113 ₫
24.476.051 ₫ total
includes taxes & fees
29 Dec - 30 Dec
COMO Castello Del Nero

IQ Hotel Firenze

IQ Hotel Firenze
4.0 star property
Historic Centre of Florence
9.6 out of 10, Exceptional, (1089)
"Beautiful hotel! Great location! Amazing breakfast! Amazing staff! "
Canada
Blair
The price is 2.560.162 ₫
3.249.436 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
IQ Hotel Firenze

Palazzo Portinari Salviati

Palazzo Portinari Salviati
Historic Centre of Florence
10.0 out of 10, Exceptional, (30)
"Wonderful. A+ rooms, service and location! Front desk was extremely helpful and responsive in getting several dinner reservations. Would absolutely stay again "
United States
Anonymous traveller
The price is 19.919.622 ₫
22.127.996 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Palazzo Portinari Salviati

Lebbiano Residence Bio Resort

Lebbiano Residence Bio Resort
3.0 star property
Scandicci
9.4 out of 10, Exceptional, (23)
"Vicino a Firenze e quindi alle principali via di scambi, ma in una tranquillità disarmante. Il silenzio è parte integrante della struttura, ma sia chiaro assolutamente positivo. La struttura è ubicata in una zona veramente bella e le stanze sono confortevoli, comode e con la possibilità di cucinare. Infine fatevi coccolare dalla colazione servita in compagnia di uno stupendo gattone rosso e dalla bella Camilla. ;-)"
Italy
Matteo
The price is 2.754.599 ₫
3.802.954 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Lebbiano Residence Bio Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santissima Annunziata Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Santissima Annunziata?
Soothe the senses with some time in one of our wonderful spa hotels. Travellers like the gardens in Santissima Annunziata. Enjoy the museums and cafes during your holiday. Hotels with spas are a great way to break away from your routine and add a layer of luxury to your stay.
How many spa hotels will I find in Santissima Annunziata?
Among Expedia's 484 accommodation options in Santissima Annunziata, there are 4 spa hotels.
What's there to see and do in Santissima Annunziata?
Enjoy all that Santissima Annunziata has to offer when you visit Statue of David, Gallery of the Academy of Florence and Piazza Donatello. If you have some spare time during your trip, you might want to check out Palazzo Capponi and Piazza Massimo D'Azeglio.
What is a Santissima Annunziata spa hotel?
Spa hotels in Santissima Annunziata provide lodging and have a full on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.