Santissima Annunziata Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Santissima Annunziata

Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Find hotels in Historic Centre of Florence

Top hotels in Santissima Annunziata

Forte16 View & Spa

Forte16 View & Spa

Viale Antonio Gramsci 16 Florence FI
Fully refundableReserve now, pay when you stay
The price is 2.963.427 ₫ per night from 9 Feb to 10 Feb
2.963.427 ₫
3.628.801 ₫ total
9 Feb - 10 Feb
includes taxes & fees
9.4/10 Exceptional! (902 reviews)
Quality of the hotel & the staff, helpful and friendly, well equipped and comfortable rooms, great location only minor negative being noise but no worse than any other city centre hotel and slept very well despite this. Would return in a flash. Would

Reviewed on 16 Jan 2026

Forte16 View & Spa
Four Seasons Hotel Firenze

Four Seasons Hotel Firenze

5 out of 5
Borgo Pinti, 99 Florence FI
Fully refundableReserve now, pay when you stay
The price is 20.911.733 ₫ per night from 9 Feb to 10 Feb
20.911.733 ₫
23.494.948 ₫ total
9 Feb - 10 Feb
includes taxes & fees
9.6/10 Exceptional! (293 reviews)
Very good and clean, the staff always professional and friendly. The room service spectacular, they prepared something special for our honeymoon.

Reviewed on 28 Jan 2026

Four Seasons Hotel Firenze
Hotel Astro Mediceo

Hotel Astro Mediceo

3 out of 5
Via Frà Bartolommeo 54/56 Florence FI
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (351 reviews)
Clean room, friendly staff, and tasty breakfast!

Reviewed on 30 Oct 2025

Get rates
Hotel Astro Mediceo
See all 476 properties in Santissima Annunziata
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santissima Annunziata holiday package cost?
Custom build your Santissima Annunziata package from an affordable . Pick from any combination of hotels, flights and rental cars to craft the escape you've been dreaming of. Be sure to add on some activities and experiences!
How do I get a cheap travel package to Santissima Annunziata?
Just think of all the wonderful things you could do in Santissima Annunziata with a wad of extra cash in your wallet. Watch your savings stack up when you bundle your flights and hotel into a Santissima Annunziata holiday package. You have plenty of choice with Expedia too. In fact, you can choose from more than 550 airlines and 1null000null000 hotels around the world. Whether you're taking off with the family or flying solo, organising a getaway to Santissima Annunziata is better with a package.
How far in advance should I book my Santissima Annunziata holiday?
It can be hard to know exactly when the best time is to book your trip to Santissima Annunziata. But generally the earlier you book, the more affordable the prices. Sometimes, you can secure your flights and hotels up to 12 months before your departure date. If you're hoping for a last-minute getaway, no need to worry! There are fabulous deals advertised on Expedia every single day.
What does an Expedia Santissima Annunziata travel package include?
With Expedia, you can select any combination of car rentals, flights and hotels to build your perfect Santissima Annunziata package. Once you've made your booking, you can add on fun stuff like tours and experiences. Remember, the more you bundle, the more cash you'll save!
What should I know before booking a Santissima Annunziata travel package?
Our prices are already low. However, you'll grab even more savings when you book your flights, hotels and car rentals together. With an Expedia package, you'll get transparent pricing and tons of choice.
Can I choose my airline with a Santissima Annunziata Expedia holiday package?
Yes, the choice is all yours. We offer more than 550 partner airlines all over the world, so you can customize your Santissima Annunziata adventure according to your travel preferences.
If I'm not able to travel, can I cancel my Santissima Annunziata holiday package?
You can. We understand that things don't always go to plan, so we're happy to help if you have to make changes to your Santissima Annunziata holiday package. It may be possible to cancel or change your itinerary for free if you've booked within 24 hours. Your airline, hotel or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the nitty-gritty on change fees.

Popular places to visit

Accademia Gallery which includes street scenes as well as a large group of people

Gallery of the Academy of Florence

You can browse the exhibits at Gallery of the Academy of Florence, a museum with a story of its own, during your trip to Florence. Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Gallery of the Academy of Florence
0_BXP44952

Statue of David

You can learn about the history of Florence with a trip to Statue of David. Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Statue of David
Province of Florence featuring street scenes, a square or plaza and a statue or sculpture

Santissima Annunziata Square

Find out about the history of Florence with a stop at Santissima Annunziata Square. Experience the acclaimed art galleries and fascinating museums in this vibrant area.

Santissima Annunziata Square