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20 Dec - 21 Dec
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21 Dec - 22 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Santo Antonio hotels

Restaurant
HOTEL RAIZ

HOTEL RAIZ

HOTEL RAIZ
3.0 star property
5.4 km from Santo Antonio
8.6 out of 10, Excellent, (4)
"Otima"
Brazil
STHEFANNY SABRINA
The price is 868.005 ₫
885.365 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
HOTEL RAIZ
Shared kitchen facilities
Alvorada Suíte

Alvorada Suíte

Alvorada Suíte
2.5 star property
Alvorada, 4.1 km from Santo Antonio
8.4 out of 10, Very good, (17)
"Hotel bem humilde. A cama é limpa mas não espere nada alem disso."
Brazil
Anonymous traveller
The price is 605.016 ₫
617.121 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Alvorada Suíte
Private beach, white sand, sun-loungers, beach towels
Amazon Ecopark Jungle Lodge

Amazon Ecopark Jungle Lodge

Amazon Ecopark Jungle Lodge
3.5 star property
15.4 km from Santo Antonio
8.0 out of 10, Very good, (141)
"Outstanding, in every aspect. The lodge was well maintained, the staff was very friendly, and we saw interesting toucans, monkeys and even a sloth just outside the restaurant. Our guide ( Mr. Shamir Kapoor) was fantastic and the excursions to the monkey island and pink dolphins were awesome."
United States
Ravindra
Amazon Ecopark Jungle Lodge
Courtyard
FLAT TROPICAL

FLAT TROPICAL

FLAT TROPICAL
2.0 star property
4.2 km from Santo Antonio
8.6 out of 10, Excellent, (4)
"Old, Very limited parking, Insects inside room"
United States
Alberto
The price is 1.665.640 ₫
1.698.953 ₫ total
includes taxes & fees
26 Dec - 27 Dec
FLAT TROPICAL
Outdoor pool, pool loungers
Hotel Villa Amazonia

Hotel Villa Amazonia

Hotel Villa Amazonia
4.0 star property
Manaus Centro, 2.6 km from Santo Antonio
9.6 out of 10, Exceptional, (373)
"Charming hotel, great staff, spacious rooms."
United States
Joan
Hotel Villa Amazonia
1 bedroom, desk, laptop workspace, free WiFi
Hotel Manaus - Dom Pedro l

Hotel Manaus - Dom Pedro l

Hotel Manaus - Dom Pedro l
2.0 star property
Dom Pedro I, 3.3 km from Santo Antonio
7.0 out of 10, Good, (19)
"A great place if you like having a kitchen to save money on restaurant costs. They have a keypad code to enter the building so it doesn’t matter what time you arrive to check in. Grocery store in walking distance. Laundromat around the corner."
United States
Matthew J
The price is 680.928 ₫
830.732 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Manaus - Dom Pedro l
Terrace/patio
Boutique Hotel Casa Teatro

Boutique Hotel Casa Teatro

Boutique Hotel Casa Teatro
2.5 star property
Manaus Centro, 2.9 km from Santo Antonio
7.6 out of 10, Good, (125)
"Very basic, clean, convenient."
United States
Lilit
The price is 899.288 ₫
917.279 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Boutique Hotel Casa Teatro
TV, printers
Casa Perpetua hotel d charm

Casa Perpetua hotel d charm

Casa Perpetua hotel d charm
3.0 star property
Manaus Centro, 2.7 km from Santo Antonio
8.8 out of 10, Excellent, (104)
"Great location and cozy hotel"
Canada
Daniel
The price is 2.891.593 ₫
2.949.413 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Casa Perpetua hotel d charm
Reception
Galeria & Hotel Farol da Barra

Galeria & Hotel Farol da Barra

Galeria & Hotel Farol da Barra
2.5 star property
2.4 km from Santo Antonio
8.2 out of 10, Very good, (24)
" Boa localização. café da manhã bom"
Brazil
CLAUDIA
The price is 926.157 ₫
944.671 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Galeria & Hotel Farol da Barra
Sun deck
Flat no Tropical Executive Hotel

Flat no Tropical Executive Hotel

Flat no Tropical Executive Hotel
2.0 star property
Ponta Negra, 9.1 km from Santo Antonio
6.0 out of 10, (7)
"Ac wasn’t cold and no parking "
United States
Mirna
The price is 1.993.776 ₫
2.033.652 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Flat no Tropical Executive Hotel
Restaurant
Casa Paraense

Casa Paraense

Casa Paraense
2.5 star property
Planalto, 6.2 km from Santo Antonio
8.8 out of 10, Excellent, (21)
"Nice courteous staff Relaxed check in"
United States
Elias
The price is 586.405 ₫
598.133 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Casa Paraense
Luxury Double Room | Hypo-allergenic bedding, free WiFi, bed sheets
pousada ponta negra

pousada ponta negra

pousada ponta negra
3.0 star property
4.1 km from Santo Antonio
8.6 out of 10, Excellent, (17)
"Ao reservar, considere tratar-se de um Motel. O fato em si, não é problema. No entanto, algumas coisas se tornam complicadas. Ex.: como a recepção é de um motel, toda entrada e saída é mais difícil. Fomos bem atendidos de modo geral, tanto pela recepção, e especialmente pela sra. que prepara o café, pessoa bastante gentil."
Brazil
Sr.
The price is 918.125 ₫
1.023.645 ₫ total
includes taxes & fees
22 Dec - 23 Dec
pousada ponta negra
Fridge, microwave, oven, blender
Hotel Residencial Manaus

Hotel Residencial Manaus

Hotel Residencial Manaus
2.5 star property
Flores, 6.1 km from Santo Antonio
8.2 out of 10, Very good, (24)
"Foi boa, gratidão por nos acolher."
Brazil
janaina
The price is 448.315 ₫
573.843 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Residencial Manaus
Private kitchen
Hotel Manaus - Dom Pedro

Hotel Manaus - Dom Pedro

Hotel Manaus - Dom Pedro
2.0 star property
Dom Pedro I, 3.3 km from Santo Antonio
7.4 out of 10, Good, (31)
"1 bathroom 2 rooms not safe not privet,poor comunication with owners . Shared bathroom downside "
United States
Thomas
The price is 418.463 ₫
548.187 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Manaus - Dom Pedro
Comfort Double Room | Down duvets, pillow-top beds, minibar, free WiFi
Hotel Madu

Hotel Madu

Hotel Madu
2.5 star property
Manaus Centro, 2.7 km from Santo Antonio
8.0 out of 10, Very good, (5)
Hotel Madu
Reception
Quality Hotel Manaus

Quality Hotel Manaus

Quality Hotel Manaus
3.5 star property
Adrianopolis, 3.6 km from Santo Antonio
8.4 out of 10, Very good, (489)
"Excelente "
Brazil
celso
The price is 2.629.886 ₫
2.950.742 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Quality Hotel Manaus
Sun deck
Flat com vista no Tropical Executive

Flat com vista no Tropical Executive

Flat com vista no Tropical Executive
2.0 star property
Ponta Negra, 9.4 km from Santo Antonio
8.2 out of 10, Very good, (13)
"Loved the pool, breakfast is good. And the hotel staff were great."
United States
Jonathan
The price is 1.658.708 ₫
1.691.882 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Flat com vista no Tropical Executive
Terrace/patio
AMAZON HOME AND JUNGLE TRIPS

AMAZON HOME AND JUNGLE TRIPS

AMAZON HOME AND JUNGLE TRIPS
3.5 star property
Tarumã, 11.1 km from Santo Antonio
The price is 1.861.617 ₫
1.898.850 ₫ total
includes taxes & fees
27 Dec - 28 Dec
AMAZON HOME AND JUNGLE TRIPS
Sun deck
Flat em Tropical Executive Hotel

Flat em Tropical Executive Hotel

Flat em Tropical Executive Hotel
2.0 star property
Ponta Negra, 9.1 km from Santo Antonio
8.0 out of 10, Very good, (10)
"The only good thing is the view of the pool to the river "
United States
Marina
The price is 1.675.437 ₫
1.708.945 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Flat em Tropical Executive Hotel
Outdoor pool, pool umbrellas, pool loungers
Hotel Casa do Bispo

Hotel Casa do Bispo

Hotel Casa do Bispo
3.5 star property
Manaus Centro, 2.9 km from Santo Antonio
8.8 out of 10, Excellent, (97)
"Great location, several shops and restaurants near by. The rooms on the back is very quiet. Very clean. "
United States
Eduardo
The price is 2.129.906 ₫
2.172.505 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hotel Casa do Bispo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Antonio

Find the best Santo Antonio areas for the activities you enjoy most.

Manaus Centro

Manaus Centro is noteworthy for its theatres, and you can make a stop at top attractions like Teatro Amazonas and Port of Manaus.

Cidade Nova Manaus

While Cidade Nova Manaus isn't home to many top sights, Amazon Arena and Archipelago of Anavilhanas are some notable places to visit nearby.

Ponta Negra

Visitors to Ponta Negra enjoy its river views, and if you want to do some exploring, Ponta Negra Beach is worth a stop.

Adrianopolis

Visitors to Adrianopolis enjoy its shopping, and if you want to do some exploring, Manauara Shopping is worth a stop.

Tarumã

When in Tarumã, you can plan a visit to Amazon Arena and Ponta Negra Beach, some noteworthy sights in the nearby area.

Top Santo Antonio Hotel Reviews

Frequently asked questions

What is Santo Antonio like?
Travellers to the Santo Antonio neighbourhood in Manaus will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Santo Antonio, will I receive a refund?
Yes, most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Santo Antonio.
What can I see and do in this Manaus neighbourhood?
A few places to visit in the area around Santo Antonio include Ingreja Matriz, CIGS Zoo and Museu da Cidade de Manaus. When you're sightseeing in Manaus, Palacio da Justica and Teatro Amazonas are also worth a stop.