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14 Dec - 15 Dec
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15 Dec - 16 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Santo Antonio hotels

42-inch flat-screen TV with satellite channels, TV
Alvorada Suíte

Alvorada Suíte

Alvorada Suíte
2.5 star property
Alvorada, 4.1 km from Santo Antonio
8.4 out of 10, Very good, (17)
"Hotel bem humilde. A cama é limpa mas não espere nada alem disso."
Brazil
Anonymous traveller
The price is 618.808 ₫
631.189 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Alvorada Suíte
Restaurant
HOTEL RAIZ

HOTEL RAIZ

HOTEL RAIZ
3.0 star property
5.4 km from Santo Antonio
8.6 out of 10, Excellent, (4)
"Otima"
Brazil
STHEFANNY SABRINA
The price is 887.792 ₫
905.547 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
HOTEL RAIZ
Terrace/patio
Hotel Saint Paul

Hotel Saint Paul

Hotel Saint Paul
3.5 star property
Manaus Centro, 2.8 km from Santo Antonio
8.0 out of 10, Very good, (614)
"Great place to stay nearby most historic sites "
United States
Cileia
Hotel Saint Paul
Terrace/patio
Hotel casa dos Frades

Hotel casa dos Frades

Hotel casa dos Frades
3.0 star property
Manaus Centro, 2.9 km from Santo Antonio
8.4 out of 10, Very good, (216)
"Perfect location and such a unique decor! "
United States
William
The price is 1.234.461 ₫
1.259.150 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel casa dos Frades
Front of property
FLAT TROPICAL

FLAT TROPICAL

FLAT TROPICAL
2.0 star property
4.2 km from Santo Antonio
8.6 out of 10, Excellent, (4)
"Old, Very limited parking, Insects inside room"
United States
Alberto
The price is 1.619.382 ₫
1.651.770 ₫ total
includes taxes & fees
15 Dec - 16 Dec
FLAT TROPICAL
Luxury Double Room | Hypo-allergenic bedding, free WiFi, bed sheets
pousada ponta negra

pousada ponta negra

pousada ponta negra
3.0 star property
4.1 km from Santo Antonio
8.6 out of 10, Excellent, (17)
"as comidas do cardápio são meio caras e vem bem pouquinho. A estrutura da cama também não é confortável, é literalmente em cima do mármore "
Brazil
Fernanda
The price is 939.054 ₫
1.046.978 ₫ total
includes taxes & fees
22 Dec - 23 Dec
pousada ponta negra
TV, printers
Casa Perpetua hotel d charm

Casa Perpetua hotel d charm

Casa Perpetua hotel d charm
3.0 star property
Manaus Centro, 2.7 km from Santo Antonio
8.8 out of 10, Excellent, (104)
"Great location and cozy hotel"
Canada
Daniel
The price is 1.325.387 ₫
1.351.895 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Casa Perpetua hotel d charm
Restaurant
Casa Paraense

Casa Paraense

Casa Paraense
2.5 star property
Planalto, 6.2 km from Santo Antonio
8.8 out of 10, Excellent, (21)
"Nice courteous staff Relaxed check in"
United States
Elias
The price is 599.773 ₫
611.768 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Casa Paraense
Comfort Double Room | Down duvets, pillow-top beds, minibar, free WiFi
Hotel Madu

Hotel Madu

Hotel Madu
2.5 star property
Manaus Centro, 2.7 km from Santo Antonio
7.4 out of 10, Good, (3)
Hotel Madu
Interior
Hotel Manaus - Dom Pedro

Hotel Manaus - Dom Pedro

Hotel Manaus - Dom Pedro
2.0 star property
Dom Pedro I, 3.3 km from Santo Antonio
7.4 out of 10, Good, (30)
"1 bathroom 2 rooms not safe not privet,poor comunication with owners . Shared bathroom downside "
United States
Thomas
The price is 441.071 ₫
577.803 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Manaus - Dom Pedro
Economy Double Room, 1 Bedroom | Minibar, desk, iron/ironing board, free WiFi
Hotel Fortaleza III Manaus

Hotel Fortaleza III Manaus

Hotel Fortaleza III Manaus
2.5 star property
Manaus Centro, 2.7 km from Santo Antonio
8.0 out of 10, Very good, (55)
" I liked this hotel very much because of You location close to the comercial áreas and the city centre"
Mexico
antonio alejandro
The price is 518.352 ₫
528.742 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Fortaleza III Manaus
Terrace/patio
Boutique Hotel Casa Teatro

Boutique Hotel Casa Teatro

Boutique Hotel Casa Teatro
2.5 star property
Manaus Centro, 2.9 km from Santo Antonio
7.6 out of 10, Good, (125)
"Very basic, clean, convenient."
United States
Lilit
The price is 1.161.825 ₫
1.185.082 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Boutique Hotel Casa Teatro
Outdoor pool, pool loungers
Blue Tree Premium Manaus

Blue Tree Premium Manaus

Blue Tree Premium Manaus
3.5 star property
Adrianopolis, 3.8 km from Santo Antonio
8.4 out of 10, Very good, (627)
"Enjoyed my stay. Lovely big spacious room, huge bed really comfortable. Staff were excellent in alll areas ..housekeeping, restaurant, reception desk. Willing to do anything to help. Would stay again"
Australia
Christine
The price is 2.005.725 ₫
2.045.840 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Blue Tree Premium Manaus
1 bedroom, desk, laptop workspace, free WiFi
Hotel Manaus - Dom Pedro l

Hotel Manaus - Dom Pedro l

Hotel Manaus - Dom Pedro l
2.0 star property
Dom Pedro I, 3.3 km from Santo Antonio
6.8 out of 10, (18)
"A great place if you like having a kitchen to save money on restaurant costs. They have a keypad code to enter the building so it doesn’t matter what time you arrive to check in. Grocery store in walking distance. Laundromat around the corner."
United States
Matthew J
The price is 696.450 ₫
849.669 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Manaus - Dom Pedro l
Laptop workspace, blackout curtains, free WiFi, bed sheets
Hotel Residencial Manaus

Hotel Residencial Manaus

Hotel Residencial Manaus
2.5 star property
Flores, 6.1 km from Santo Antonio
8.2 out of 10, Very good, (24)
"Foi boa, gratidão por nos acolher."
Brazil
janaina
The price is 458.535 ₫
586.925 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Residencial Manaus
Terrace/patio
AMAZON HOME AND JUNGLE TRIPS

AMAZON HOME AND JUNGLE TRIPS

AMAZON HOME AND JUNGLE TRIPS
3.5 star property
Tarumã, 11.1 km from Santo Antonio
The price is 1.904.055 ₫
1.942.136 ₫ total
includes taxes & fees
16 Dec - 17 Dec
AMAZON HOME AND JUNGLE TRIPS
Outdoor pool, pool umbrellas, pool loungers
Manaus Hotéis - Millennium

Manaus Hotéis - Millennium

Manaus Hotéis - Millennium
3.5 star property
Chapada, 2.5 km from Santo Antonio
8.4 out of 10, Very good, (620)
"Great property, nice views. Some areas outside of the hotel grounds are littered with garbage."
United States
Matt
Manaus Hotéis - Millennium
Outdoor pool
Hotel Intercity Manaus

Hotel Intercity Manaus

Hotel Intercity Manaus
4.0 star property
Adrianopolis, 3.6 km from Santo Antonio
8.4 out of 10, Very good, (906)
"Hotel is ok - room is spacious, breakfast is the usual Brazilian fare. "
United States
Maria de Fatima
Hotel Intercity Manaus
Garden
Hotel Casa do Bispo

Hotel Casa do Bispo

Hotel Casa do Bispo
3.5 star property
Manaus Centro, 2.9 km from Santo Antonio
8.8 out of 10, Excellent, (96)
"Great location, several shops and restaurants near by. The rooms on the back is very quiet. Very clean. "
United States
Eduardo
The price is 2.178.460 ₫
2.222.029 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Casa do Bispo
Restaurant
Galeria & Hotel Farol da Barra

Galeria & Hotel Farol da Barra

Galeria & Hotel Farol da Barra
2.5 star property
2.4 km from Santo Antonio
8.2 out of 10, Very good, (24)
" Boa localização. café da manhã bom"
Brazil
CLAUDIA
The price is 947.270 ₫
966.206 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Galeria & Hotel Farol da Barra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Antonio

Find the best Santo Antonio areas for the activities you enjoy most.

Manaus Centro

Manaus Centro is noteworthy for its theatres, and you can make a stop at top attractions like Teatro Amazonas and Port of Manaus.

Cidade Nova Manaus

While Cidade Nova Manaus isn't home to many top sights, Amazon Arena and Archipelago of Anavilhanas are some notable places to visit nearby.

Ponta Negra

Visitors to Ponta Negra enjoy its river views, and if you want to do some exploring, Ponta Negra Beach is worth a stop.

Adrianopolis

Visitors to Adrianopolis enjoy its shopping, and if you want to do some exploring, Manauara Shopping is worth a stop.

Tarumã

When in Tarumã, you can plan a visit to Amazon Arena and Ponta Negra Beach, some noteworthy sights in the nearby area.

Top Santo Antonio Hotel Reviews

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Frequently asked questions

What is Santo Antonio like?
Travellers to the Santo Antonio neighbourhood in Manaus will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Santo Antonio, will I receive a refund?
Yes, most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the top deals on offer in Santo Antonio.
What can I see and do in this Manaus neighbourhood?
A few places to visit in the area around Santo Antonio include Ingreja Matriz, CIGS Zoo and Museu da Cidade de Manaus. When you're sightseeing in Manaus, Palacio da Justica and Teatro Amazonas are also worth a stop.