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Top Trending Hotels Near Santo Domingo, Mexico City

Front of property
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4.0 star property
Venustiano Carranza, 14.5 km from Santo Domingo
8.8 out of 10, Excellent, (11829)
"Great option to stay close the airport"
United States
Alexandra
The price is 4.086.265 ₫
4.883.218 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Camino Real Aeropuerto Mexico
Breakfast, lunch, dinner served; Mexican cuisine
Hotel Catedral

Hotel Catedral

4.0 star property
Historic Center, 12.4 km from Santo Domingo
9.4 out of 10, Exceptional, (2587)
"The room was very clean and the location was great"
United States
Michele
The price is 5.907.095 ₫
7.058.990 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Hotel Catedral
Interior
Courtyard Mexico City Airport

Courtyard Mexico City Airport

4.0 star property
Venustiano Carranza, 14.8 km from Santo Domingo
9.4 out of 10, Exceptional, (1807)
"Love this place my fave hotel "
United States
Jacob
The price is 3.899.088 ₫
4.659.410 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Courtyard Mexico City Airport
Breakfast, lunch, dinner served; Mexican cuisine
Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City

4.0 star property
Historic Center, 12.2 km from Santo Domingo
9.8 out of 10, Exceptional, (2624)
"Always a great stay. Great staff, food and comfortable room."
Canada
John
The price is 4.060.298 ₫
4.852.056 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Zocalo Central & Rooftop Mexico City
Daily buffet breakfast (USD 24 per person)
Barceló México Reforma

Barceló México Reforma

4.5 star property
11.9 km from Santo Domingo
9.4 out of 10, Exceptional, (5045)
"Overall its a great hotel"
United States
Ariel
The price is 2.942.703 ₫
3.516.531 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Barceló México Reforma
Front of property
Historico Central Hotel

Historico Central Hotel

4.0 star property
Historic Center, 12 km from Santo Domingo
9.8 out of 10, Exceptional, (2397)
"Location was great and hotel was clean and comfortable "
United States
Daniela
The price is 3.167.515 ₫
3.785.180 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Historico Central Hotel
Mexican cuisine
We Hotel Aeropuerto

We Hotel Aeropuerto

3.5 star property
Venustiano Carranza, 14.1 km from Santo Domingo
8.4 out of 10, Very good, (2145)
"easy to check in, facility clean and staff friendly "
Canada
William
The price is 2.613.261 ₫
3.122.841 ₫ total
includes taxes & fees
22 Dec - 23 Dec
We Hotel Aeropuerto
Exterior
Fiesta Inn Ciudad de Mexico Aeropuerto

Fiesta Inn Ciudad de Mexico Aeropuerto

3.5 star property
Venustiano Carranza, 14.3 km from Santo Domingo
8.8 out of 10, Excellent, (3151)
"Breakfast was amazing good room "
United States
Jose
The price is 3.400.827 ₫
4.063.988 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Fiesta Inn Ciudad de Mexico Aeropuerto
Exterior
Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico

3.0 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1075)
"Great location and customer services "
Canada
Hernan
The price is 1.982.498 ₫
2.368.980 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn & Suites Mexico City - Centro Historico
View from room
Hotel Punto MX

Hotel Punto MX

3.5 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1423)
"Excellent staff and gorgeous hotel "
United States
Fernando
The price is 1.496.830 ₫
1.788.712 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Hotel Punto MX
Suite | In-room safe, desk, soundproofing, iron/ironing board
Grand Prix-WeEnjoyHotels-Aeropuerto

Grand Prix-WeEnjoyHotels-Aeropuerto

3.5 star property
10.8 km from Santo Domingo
9.0 out of 10, Wonderful, (3789)
"Excelente hotel"
Mexico
Samgamer
The price is 2.194.886 ₫
2.622.889 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Grand Prix-WeEnjoyHotels-Aeropuerto
Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout curtains
Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

3.0 star property
14.7 km from Santo Domingo
9.2 out of 10, Wonderful, (1036)
"Excellent stay!"
United States
Derek
The price is 1.745.318 ₫
2.085.655 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Mexico Basilica by IHG
Deluxe Suite, 1 King Bed | Egyptian cotton sheets, premium bedding, down duvets, in-room safe
Econo Express Hotel

Econo Express Hotel

3.5 star property
Benito Juarez, 6.4 km from Santo Domingo
9.0 out of 10, Wonderful, (1577)
"Courteous staff and the room was impeccable! Super happy with my stay, I’ll most definitely be booking this hotel for any future trips to Mexico City. "
United States
Alberto
Econo Express Hotel
Indoor pool, outdoor pool
Hilton Mexico City Reforma

Hilton Mexico City Reforma

4.5 star property
Reforma, 12 km from Santo Domingo
9.4 out of 10, Exceptional, (1048)
"great place . friendly staff and everything was to perfection."
United States
Adriana
The price is 4.683.387 ₫
5.596.648 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hilton Mexico City Reforma
Deluxe Double Room | In-room safe, blackout curtains, soundproofing, iron/ironing board
Punta Alameda

Punta Alameda

2.0 star property
Downtown Mexico City, 11.6 km from Santo Domingo
9.4 out of 10, Exceptional, (192)
"Regular cleaning, friendly staff"
Canada
Mukul
Punta Alameda
Restaurant
NH Collection Mexico City Airport T2

NH Collection Mexico City Airport T2

4.0 star property
Venustiano Carranza, 13.7 km from Santo Domingo
8.6 out of 10, Excellent, (3490)
"Love to stay at "
United States
ZEESHAN
The price is 4.388.385 ₫
5.244.120 ₫ total
includes taxes & fees
23 Dec - 24 Dec
NH Collection Mexico City Airport T2
Exterior
Fiesta Americana Reforma

Fiesta Americana Reforma

4.0 star property
Juárez, 11.6 km from Santo Domingo
9.2 out of 10, Wonderful, (4038)
"Had a fantastic stay "
United States
Elridge Karl
The price is 2.980.074 ₫
3.561.189 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Fiesta Americana Reforma
Outdoor pool
Galeria Plaza Reforma

Galeria Plaza Reforma

4.0 star property
Zona Rosa, 10.7 km from Santo Domingo
9.4 out of 10, Exceptional, (3151)
"Always a great place I stay at. "
United States
Noe
The price is 4.112.364 ₫
4.914.326 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Galeria Plaza Reforma
Lobby
Geneve Ciudad de México

Geneve Ciudad de México

4.0 star property
Zona Rosa, 10.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1708)
"Great location, customer service and the hotel was nice and clean "
United States
Victor
The price is 2.775.551 ₫
3.316.783 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Geneve Ciudad de México
Exterior
Hotel PF

Hotel PF

3.5 star property
Zona Rosa, 10.6 km from Santo Domingo
9.0 out of 10, Wonderful, (2225)
"The room was very clean, amenities were great"
United States
Carmen
The price is 1.884.730 ₫
2.252.253 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel PF
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Domingo

Find the best Santo Domingo areas for the activities you enjoy most.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Polanco which includes heritage architecture, a church or cathedral and a park

Polanco

If you're spending time in Polanco, you might enjoy attractions like Paseo de la Reforma and Avenida Presidente Masaryk. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Polanco Station to see more of the city.

La Condesa featuring café scenes

La Condesa

Spend some time visiting places like Blackberry Auditorium while getting to know La Condesa, and be sure to check out the abundant dining options. You can hop aboard the metro at Patriotism Station or Chilpancingo Station to see more of the area.

Metropolitan Cathedral which includes a church or cathedral, heritage elements and heritage architecture

Historic Center

Consider a visit to Palacio de Bellas Artes and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.

Reforma which includes a city, night scenes and central business district

Reforma

Consider a visit to Paseo de la Reforma and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Domingo Hotel Reviews

ULIV Mexico City

ULIV Mexico City

10/10 Excellent
"Very cool views "
Lhamo 4-night trip
Posted 4 days ago
ULIV Mexico City

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Frequently asked questions

What is Santo Domingo like?
Travellers to Mexico City's Santo Domingo neighbourhood will be sure to enjoy a stay here.
How many hotels will I find in the Santo Domingo area?
Book one of Expedia's 5 hotels and other accommodation options in Santo Domingo and start exploring everything Mexico City has to offer.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best deals available in Santo Domingo.
What are the top things to see and do in Santo Domingo?
Parroquia de San Juan Bautista, Casa del Teatro and Museo Diego Rivera Anahuacalli are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Museo de la Ciudad and Hidalgo Plaza are a couple of additional sights to visit in Mexico City.