Search Hotels in Santy - La Plaine, Lyon

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santy - La Plaine hotels

Exterior
Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu

3.0 star property
4.1 km from Santy - La Plaine
9.0 out of 10, Wonderful, (1188)
"Nice place to stay."
United States
Yuanmei
The price is 2.134.293 ₫
2.462.500 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Campanile PRIME - Lyon Centre Gare Part Dieu
Indoor pool
Grand Hotel Des Terreaux

Grand Hotel Des Terreaux

4.0 star property
5.9 km from Santy - La Plaine
8.8 out of 10, Excellent, (1001)
"helpful staff, hotel location, amenities"
Canada
Rick
The price is 2.893.911 ₫
3.358.844 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Grand Hotel Des Terreaux
View from property
Fourvière Hôtel Lyon

Fourvière Hôtel Lyon

4.0 star property
Fourvière, 6.3 km from Santy - La Plaine
9.2 out of 10, Wonderful, (1005)
"This property was excellent "
United States
Ed
Fourvière Hôtel Lyon
Front of property
ibis Styles Lyon Centre - Gare Part Dieu Hotel

ibis Styles Lyon Centre - Gare Part Dieu Hotel

3.0 star property
4.1 km from Santy - La Plaine
8.8 out of 10, Excellent, (1001)
"Breakfast was great. The shower head was fantastic."
United States
Ian
The price is 2.966.248 ₫
3.377.651 ₫ total
includes taxes & fees
24 Dec - 25 Dec
ibis Styles Lyon Centre - Gare Part Dieu Hotel
View from room
Carlton Hotel Lyon - MGallery Collection

Carlton Hotel Lyon - MGallery Collection

4.0 star property
Les Cordeliers, 5.3 km from Santy - La Plaine
9.4 out of 10, Exceptional, (1000)
"Everything about this hotel was fantastic"
United States
Gerald
The price is 5.072.083 ₫
5.754.833 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Carlton Hotel Lyon - MGallery Collection
Reception
Hôtel Mercure Lyon Centre - Gare Part Dieu

Hôtel Mercure Lyon Centre - Gare Part Dieu

4.0 star property
4.1 km from Santy - La Plaine
9.2 out of 10, Wonderful, (1000)
"Clean room, staff was at the desk for late arrival, restaurant on the premise."
United States
GIANNI
The price is 2.964.295 ₫
3.436.266 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hôtel Mercure Lyon Centre - Gare Part Dieu
Suite Supérieure Ocre, 22 Rue du Boeuf 69005 Lyon | Premium bedding, minibar, in-room safe, blackout curtains
MiHotel La Tour Rose

MiHotel La Tour Rose

Old Lyon, 5.9 km from Santy - La Plaine
8.6 out of 10, Excellent, (166)
"Tons of restaurants, all good."
United States
jeffrey
The price is 2.873.734 ₫
3.319.034 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
MiHotel La Tour Rose
Courtyard view
Académie Hôtel Lyon

Académie Hôtel Lyon

4.0 star property
Old Lyon, 6.1 km from Santy - La Plaine
9.4 out of 10, Exceptional, (201)
"Clean room, nice staff. "
Canada
Pamela
The price is 3.337.029 ₫
3.846.274 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Académie Hôtel Lyon
Front of property
Mercure Lyon Centre Beaux Arts

Mercure Lyon Centre Beaux Arts

4.0 star property
Les Cordeliers, 5.4 km from Santy - La Plaine
9.0 out of 10, Wonderful, (1000)
"Relatively basic hotel in a great location with excellent staff."
United Kingdom
Ian
The price is 3.029.489 ₫
3.508.007 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Mercure Lyon Centre Beaux Arts
Exterior
Le Phenix Hotel

Le Phenix Hotel

4.0 star property
Old Lyon, 6.2 km from Santy - La Plaine
9.2 out of 10, Wonderful, (1002)
"Fantastic location with excellent rooms"
United States
Hudson
The price is 3.124.465 ₫
3.612.423 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Le Phenix Hotel
Lobby
Campanile Lyon Centre-Berges du Rhône

Campanile Lyon Centre-Berges du Rhône

3.0 star property
3rd Arrondissement, 4.6 km from Santy - La Plaine
7.8 out of 10, Good, (1001)
"Good stay for one night in Lyon. Good basic hotel. "
United Kingdom
Olivia
The price is 1.869.529 ₫
2.171.260 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Campanile Lyon Centre-Berges du Rhône
Lobby sitting area
The Ruck Hotel

The Ruck Hotel

4.0 star property
Gerland, 4 km from Santy - La Plaine
9.0 out of 10, Wonderful, (208)
"Wasn’t a very good breakfast choice , staff were very helpful and efficient "
United Kingdom
yasmin
The price is 5.015.727 ₫
5.692.842 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
The Ruck Hotel
Breakfast, lunch, dinner served; Italian cuisine
MOB Hotel Lyon Confluence

MOB Hotel Lyon Confluence

3.0 star property
La Confluence, 5.1 km from Santy - La Plaine
8.6 out of 10, Excellent, (898)
"Hotel and staff were nice only thin is its next to railroad and sometimes its loud"
United States
Araceli
The price is 2.098.883 ₫
2.423.549 ₫ total
includes taxes & fees
22 Dec - 23 Dec
MOB Hotel Lyon Confluence
Lounge
ibis Lyon Part Dieu Les Halles

ibis Lyon Part Dieu Les Halles

3.0 star property
Part Dieu - Bir Hakeim, 4.7 km from Santy - La Plaine
8.2 out of 10, Very good, (1003)
"Clean room, very lovely staff, nice brekki, great location "
Ireland
Aida Aboonasr
The price is 1.783.041 ₫
2.076.123 ₫ total
includes taxes & fees
24 Dec - 25 Dec
ibis Lyon Part Dieu Les Halles
Terrace/patio
Hôtel Mercure Lyon Centre Plaza République

Hôtel Mercure Lyon Centre Plaza République

4.0 star property
Les Cordeliers, 5.2 km from Santy - La Plaine
8.4 out of 10, Very good, (684)
"Location excellent"
United States
DIDEM
The price is 2.821.730 ₫
3.279.445 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hôtel Mercure Lyon Centre Plaza République
Terrace/patio
Collège Hôtel

Collège Hôtel

4.0 star property
Old Lyon, 6.1 km from Santy - La Plaine
8.4 out of 10, Very good, (762)
"Loved it"
United States
Steven
Collège Hôtel
Fountain
Hôtel Bayard Bellecour

Hôtel Bayard Bellecour

4.0 star property
Bellecour - Hôtel Dieu, 5.1 km from Santy - La Plaine
8.4 out of 10, Very good, (418)
"Very good hotel in a central area, quiet room and very nice staff! "
United States
Sandrine
Hôtel Bayard Bellecour
Desk, soundproofing, free WiFi
Le Lumière

Le Lumière

3.0 star property
2.5 km from Santy - La Plaine
9.2 out of 10, Wonderful, (62)
"Very nice property. Staff was very friendly."
United States
Minerva
The price is 1.606.997 ₫
1.882.475 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Le Lumière
Garden
Appart'hôtel Odalys City - Lyon Centre Confluence

Appart'hôtel Odalys City - Lyon Centre Confluence

5.2 km from Santy - La Plaine
8.0 out of 10, Very good, (793)
"The property was good and well maintained but the homeless people camped nearby felt unsafe."
United Kingdom
Elaine
The price is 1.830.473 ₫
2.114.196 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Appart'hôtel Odalys City - Lyon Centre Confluence
Indoor spa tub
B&B Home Lyon Centre Berthelot

B&B Home Lyon Centre Berthelot

7th Arrondissement, 2.7 km from Santy - La Plaine
8.4 out of 10, Very good, (828)
"The stay was very comfortable and everything was clean, and even got to enjoy the jacuzzi and sauna for one night! Was easy to get to my train station for travel the next day. "
United States
Gail
B&B Home Lyon Centre Berthelot
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santy - La Plaine

Find the best Santy - La Plaine areas for the activities you enjoy most.

Lyon City Centre

Gourmet restaurants interesting history and top sights from Bellecour Square to Hôtel-Dieu – discover Lyon City Centre, a destination also famous for its shopping.

Lyon showing a city, a river or creek and a statue or sculpture

Old Lyon

If you're spending time in Old Lyon, you might enjoy attractions like Lyon Cathedral and Palais de Justice de Lyon. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Vieux Lyon Station to see more of the city.

Bellecour Square which includes a statue or sculpture, a river or creek and a bridge

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

3rd Arrondissement

Noted for its shopping and river views, there's plenty to explore in 3rd Arrondissement. Top attractions like Part Dieu Mall and Halles de Lyon - Paul Bocuse are major draws, and you can hop on the metro at Dauphine - Lacassagne Tram Stop or Archives Départementales Tram Stop to see more of the city.

Lyon showing a church or cathedral and heritage architecture

Les Cordeliers

Take time in Les Cordeliers to visit attractions like Museum of Fine Arts of Lyon and Place des Terreaux. You might also appreciate the abundant dining options, and you can hop on the metro at Cordeliers Bourse Station to see more of the city.

Top Santy - La Plaine Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Santy - La Plaine like?
Travellers to Lyon's Santy - La Plaine neighbourhood will be sure to enjoy a stay here.
If I need to cancel my hotel reservation in Santy - La Plaine, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to review the best deals available in Santy - La Plaine.
What is there to do around this Lyon neighbourhood?
Wakoo Park, Maison de la Danse and Tony Garnier Housing Project are just a few of the places to visit in and around Santy - La Plaine. When you're sightseeing in Lyon, Bulle d'Air Park and Hippodrome Bron-Parilly are also worth a stop.