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Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with fitness centre and 24-hour front desk

Choose dates to view prices

Photo gallery for Comfort Inn & Suites Sikeston I-55

Exterior
Indoor pool
Lobby
1 bedroom, desk, free WiFi, bed sheets
Breakfast area
Just off I-55, Comfort Inn & Suites Sikeston I-55 provides a practical base for travelers. Guests can swim in the indoor pool, use the laundry facilities, connect with in-room WiFi, maintain fitness routines at the gym, or handle work matters in the business center.

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pet-friendly
  • Gym
  • Laundry
  • Parking included
  • Free WiFi
The current price is 2.334.025 ₫
2.660.206 ₫ total
includes taxes & fees
2 Oct - 3 Oct

Room options

Check availability for these dates

Tonight

Sept 28 - Sept 29
Check availability for tonight Sept 28 - Sept 29

Tomorrow

Sept 29 - Sept 30
Check availability for tomorrow Sept 29 - Sept 30
Available filters for rooms
Showing 5 of 5 rooms

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking | 1 bedroom, desk, free WiFi, bed sheets

Suite, 1 King Bed with Sofa bed, Non Smoking

Highlights

Air conditioning
Fridge
Separate bedroom
Sofa bed
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Standard Room, 2 Queen Beds, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)

Highlights

Air conditioning
Fridge
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 1 King Bed, Accessible, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Room, 1 King Bed, Accessible, Non Smoking

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Air conditioning
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Non Smoking

1 bedroom, desk, free WiFi, bed sheets

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)

Highlights

Air conditioning
Fridge
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

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  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
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The price is 2.670.663 ₫
3.039.588 ₫ total
includes taxes & fees
5 Oct - 6 Oct
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About the area

Sikeston is home to Comfort Inn & Suites Sikeston I-55. The area's natural beauty can be seen at Mississippi River and Central Park, while Sikeston Depot Museum and Front Street Studio & Art Gallery are cultural highlights.
Visit our Sikeston travel guideOpens in a new window
Map
109 Matthews Ln, Sikeston, MO, 63801

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.4 km
  • Central Park - 5 min drive - 5.5 km
  • Sikeston Depot Museum - 6 min drive - 5.5 km
  • Southeast Missouri State University - 41 min drive - 60.5 km
  • Isle Casino Cape Girardeau - 42 min drive - 61.2 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Cafe - ‬17 min walk
  • ‪Buffalo Wild Wings - ‬5 min drive
  • ‪Pizza Inn - ‬2 min drive
  • ‪McDonald's - ‬2 min walk
  • ‪Burger King - ‬4 min drive

About this property

Comfort Inn & Suites Sikeston I-55

Property highlights
Take advantage of laundry facilities, a gym and a business centre at Comfort Inn & Suites Sikeston I-55. Stay connected with free in-room WiFi.
Other perks include:
  • An indoor pool
  • Free self-parking
  • Laundry services, a lift and a 24-hour front desk
  • A front desk safe
  • Guest reviews speak highly of the helpful staff
Room features
All 64 rooms offer comforts such as air conditioning, in addition to amenities such as free WiFi.
Extra amenities include:
  • Bathrooms with baths or showers
  • Cable channels, coffee/tea makers and desks

Similar properties

Free daily full breakfast

Best Western Plus Sikeston

  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
8.4 out of 10, Very good, 1,015 reviews
The price is 2.154.221 ₫
2.455.273 ₫ total
includes taxes & fees
12 Oct - 13 Oct
Best Western Plus Sikeston

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business centre

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; check-in end time: anytime
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 20 per pet, per night
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 9 kg per pet)
Specific rooms only; pet-friendly rooms can be requested by contacting the property on the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Optional extras

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

Does Comfort Inn & Suites Sikeston I-55 have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of 28 Sep 2025, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on 2 Oct 2025 start from 2.334.025 ₫, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is Comfort Inn & Suites Sikeston I-55 pet-friendly?

Yes, Comfort Inn & Suites Sikeston I-55 allows cats and dogs (limit 2 total) with a maximum weight of up to 9 kg per pet. There's a fee of USD 20 per pet, per night. Service animals are exempt from fees.

How much is parking at Comfort Inn & Suites Sikeston I-55?

Self-parking is free at this property.

What time is check-in at Comfort Inn & Suites Sikeston I-55?

Check-in start time: 2:00 PM; check-in end time: anytime.

What time is check-out at Comfort Inn & Suites Sikeston I-55?

Checkout is at 11:00 AM.

Where is Comfort Inn & Suites Sikeston I-55 located?

Situated in Sikeston, this hotel is 0.4 mi (0.6 km) from City of Miner Convention Center and within 6 miles (10 km) of Sikeston Depot Museum and Central Park. Front Street Studio & Art Gallery is 9 mi (14.5 km) away.

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