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Find hotels in Sikeston, MO from 1.707.054 ₫

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Check prices for these dates

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30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for Sikeston hotels

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

1. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (649 reviews)
"Great hotel, clean spacious room, good breakfast choice"
United Kingdom
Deborah
The price is 2.460.063 ₫
2.797.707 ₫ total
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Sikeston
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

2. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,002 reviews)
"Awesome place will be staying in more of them"
United States
Tim
The price is 2.428.796 ₫
2.792.509 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Sikeston, MO
A buffet with various food items, including omelets and baked goods, served in metal containers.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (519 reviews)
"I have always have a great stay each time I’ve been here. Beds comfortable and rooms very clean."
United States
Melissa
The price is 2.506.577 ₫
2.850.605 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Sikeston Southwest by IHG
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

4. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
United States
Roslyn
The price is 2.609.941 ₫
2.968.155 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites by Marriott Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

5. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,005 reviews)
"Clean rooms, great parking, very nice staff"
United States
Shelley
The price is 2.061.595 ₫
2.349.702 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Best Western Plus Sikeston I-55
Property amenity

6. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (27 reviews)
"Great location"
United States
Rubin
The price is 2.816.669 ₫
3.203.258 ₫ total
includes taxes & fees
5 Nov - 6 Nov
TownePlace Suites by Marriott Sikeston
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

7. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.4 out of 10, Good, (1,004 reviews)
"This was a very good value. It has been the best hotel I've stayed at in awhile."
United States
David
The price is 1.713.258 ₫
1.952.685 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Days Inn and Suites by Wyndham Sikeston
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

8. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (318 reviews)
"The room was nice"
United States
Fred
The price is 2.253.335 ₫
2.568.239 ₫ total
includes taxes & fees
16 Nov - 17 Nov
Comfort Inn & Suites Sikeston I-55
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

9. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (829 reviews)
"Very clean property and the staff were very accommodating."
United States
Craig
The price is 1.795.691 ₫
2.046.866 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

10. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (689 reviews)
"It is a clean place, and we enjoyed our stay"
United States
Laura
The price is 1.497.744 ₫
1.707.054 ₫ total
includes taxes & fees
5 Nov - 6 Nov
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a desk, a chair, a TV, and a mirror.

11. Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (163 reviews)
"It was an ok room for the price paid."
United States
Marianne
The price is 1.460.792 ₫
1.737.977 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Country Yard Inn and Suite
A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

12. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,008 reviews)
"Great stay! Hot tub was enjoyable and the staff was super friendly!"
United States
Chris
The price is 2.583.842 ₫
2.914.935 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Drury Plaza Hotel Cape Girardeau Conference Center
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

13. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
United States
Rebecca
The price is 2.454.895 ₫
2.794.014 ₫ total
includes taxes & fees
26 Nov - 27 Nov
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

14. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (237 reviews)
"Great hotel…!!"
United States
Carlos
The price is 2.613.817 ₫
2.948.752 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

15. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (882 reviews)
"Breakfast was good."
United States
J
The price is 2.064.696 ₫
2.234.517 ₫ total
includes taxes & fees
1 Nov - 2 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

16. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.2 out of 10, Wonderful, (1,003 reviews)
"Room was clean and staff was very friendly"
United States
Troy
The price is 1.860.294 ₫
2.098.671 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Pear Tree Inn Cape Girardeau West
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

17. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"The food was excellent"
United States
DENNIS
The price is 2.325.432 ₫
2.623.413 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Drury Inn & Suites Cape Girardeau
A spacious lobby with marble flooring, elegant seating, and a grand staircase.

18. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (555 reviews)
"The staff was very friendly and rooms were great!"
United States
Jacqueline
The price is 3.000.140 ₫
3.399.579 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Courtyard by Marriott Cape Girardeau Downtown
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

19. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (694 reviews)
"Clean, quiet, comfortable room. Very comfortable beds."
United States
Renee
The price is 2.953.626 ₫
3.332.104 ₫ total
includes taxes & fees
28 Oct - 29 Oct
The Riverview
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

20. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (854 reviews)
"Stayed here overnight for a wedding. Room was clean and they allowed us to check in early with no fee. Location is ideal, being walking distance from a Cracker Barrel and a breakfast place. Stores like Target and Walmart are only about a 5 minute drive."
United States
Brittany
The price is 2.415.617 ₫
2.725.155 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn Cape Girardeau I 55 East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sikeston attractions

Sikeston Depot Museum

7.6/10 (57 reviews)
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
See properties

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
A tree with sunlight filtering through its leaves, creating a warm glow.

Top Sikeston Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"The staff was very polite, helpful and courteous. The breakfast was very good, lots to choose from"
Jeremy 1-night trip
Posted 4 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

More cheap stays in Sikeston

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO
The price is 1.497.744 ₫ per night from 5 Nov to 6 Nov
1.497.744 ₫
1.707.054 ₫ total
5 Nov - 6 Nov
includes taxes & fees

Hotels in Sikeston with star rating

Frequently asked questions

What's the seasonal weather in Sikeston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.

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