
Find hotels in Sikeston, MO from 1.498.437 ₫
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Sikeston
Family friendly
Check prices for these dates
Our top choices for Sikeston hotels

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
The price is 2.486.245 ₫
2.804.833 ₫ total
includes taxes & fees
15 Mar - 16 Mar

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,007 reviews)
The price is 2.093.418 ₫
2.213.266 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,010 reviews)
The price is 2.616.838 ₫
2.952.160 ₫ total
includes taxes & fees
8 Mar - 9 Mar

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (717 reviews)
The price is 2.202.290 ₫
2.383.427 ₫ total
includes taxes & fees
5 Mar - 6 Mar

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (516 reviews)
The price is 2.520.267 ₫
2.843.213 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,005 reviews)
The price is 2.355.128 ₫
2.656.914 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (60 reviews)
The price is 2.643.271 ₫
2.992.843 ₫ total
includes taxes & fees
13 Mar - 14 Mar

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,006 reviews)
The price is 1.884.050 ₫
2.125.473 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (113 reviews)
The price is 2.553.766 ₫
2.906.543 ₫ total
includes taxes & fees
11 Mar - 12 Mar

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (747 reviews)
The price is 1.792.452 ₫
2.042.946 ₫ total
includes taxes & fees
6 Mar - 7 Mar

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (448 reviews)
The price is 2.433.903 ₫
2.755.788 ₫ total
includes taxes & fees
29 Mar - 30 Mar

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,008 reviews)
The price is 2.459.812 ₫
2.828.169 ₫ total
includes taxes & fees
8 Mar - 9 Mar

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,005 reviews)
The price is 2.135.292 ₫
2.433.641 ₫ total
includes taxes & fees
26 Mar - 27 Mar

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (493 reviews)
The price is 2.476.126 ₫
2.803.594 ₫ total
includes taxes & fees
29 Mar - 30 Mar

Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.2 out of 10, Good, (705 reviews)
The price is 1.578.111 ₫
1.780.330 ₫ total
includes taxes & fees
10 Mar - 11 Mar

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,003 reviews)
The price is 1.766.542 ₫
2.013.415 ₫ total
includes taxes & fees
5 Mar - 6 Mar

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (408 reviews)
The price is 1.831.970 ₫
2.033.028 ₫ total
includes taxes & fees
5 Mar - 6 Mar

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (490 reviews)
The price is 3.166.691 ₫
3.588.304 ₫ total
includes taxes & fees
15 Mar - 16 Mar

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (12 reviews)
The price is 3.088.178 ₫
3.496.589 ₫ total
includes taxes & fees
15 Mar - 16 Mar

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very good, (288 reviews)
The price is 2.446.989 ₫
2.788.956 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Sikeston attractions
Sikeston and related destinations
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

Top Sikeston Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
More cheap stays in Sikeston

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
The price is 1.884.050 ₫ per night from 8 Mar to 9 Mar
1.884.050 ₫
2.125.473 ₫ total
8 Mar - 9 Mar
includes taxes & fees
9/10 Wonderful! (1,006 reviews)
Hotels in Sikeston with star rating

4 Star Hotels
3 properties

2 Star Hotels
47 properties









































































