Photo by Ryan Coleman

Find hotels in Sikeston, MO from 1.701.438 ₫

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Top 10 Sikeston hotels and places to stay

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1002)
"Always the best hotel in any town. "
The price is 2.670.098 ₫
3.069.867 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Drury Inn & Suites Sikeston, MO

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1006)
"The staff was very friendly and the hotel was very clean!"
The price is 2.355.938 ₫
2.657.532 ₫ total
includes taxes & fees
14 Jul - 15 Jul
Drury Plaza Hotel Cape Girardeau Conference Center

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Front desk staff was very friendly and helpful."
The price is 1.908.260 ₫
2.152.781 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Great place to stay with kids "
The price is 2.357.828 ₫
2.710.755 ₫ total
includes taxes & fees
9 Jul - 10 Jul
Pear Tree Inn Sikeston

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
9.4 out of 10, Exceptional, (113)
"Hotel was very clean and the lady that checked us in was very friendly. "
The price is 2.425.577 ₫
2.736.390 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Fairfield Inn & Suites by Marriott Cape Girardeau

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (318)
"Everyone is very helpful, great rooms, we will stay there again."
The price is 2.756.754 ₫
3.109.922 ₫ total
includes taxes & fees
6 Jul - 7 Jul
The Riverview

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Excellent place to stay "
The price is 1.701.438 ₫
1.919.517 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Pear Tree Inn Cape Girardeau Near the Medical Center

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (721)
"Great place to stay convenient walking to multiple restaurants"
The price is 2.870.637 ₫
3.238.480 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Hampton Inn Cape Girardeau I 55 East

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (952)
"Room was very clean and staff was excellent!"
The price is 2.355.938 ₫
2.657.532 ₫ total
includes taxes & fees
14 Jul - 15 Jul
Drury Inn & Suites Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (578)
"I liked that it was quiet and breakfast was good."
The price is 2.269.806 ₫
2.456.497 ₫ total
includes taxes & fees
8 Jul - 9 Jul
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
9.6 out of 10, Exceptional, (425)
"Unique place in a historic local building - the bank vault was cool!"
The price is 3.207.002 ₫
3.633.983 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Courtyard by Marriott Cape Girardeau Downtown

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Great place to stay. "
The price is 2.748.900 ₫
3.101.143 ₫ total
includes taxes & fees
1 Aug - 2 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (360)
"Clean, great breakfast, quiet, friendly staff"
The price is 3.093.167 ₫
3.502.238 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Hampton Inn Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very good, (1003)
"We enjoyed our stay and the breakfast was good!"
The price is 2.331.627 ₫
2.657.472 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Best Western Plus Sikeston

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1004)
"Great staff "
The price is 2.355.938 ₫
2.490.765 ₫ total
includes taxes & fees
14 Jul - 15 Jul
Drury Inn & Suites Jackson MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very good, (659)
"Property is always clean, rooms are nice."
The price is 1.845.428 ₫
2.103.327 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Tru By Hilton Cape Girardeau

2.5 star property
9.8 out of 10, Exceptional, (35)
"It was a quick stay for work but the place was very nice and clean! I like the way they do breakfast too. "
The price is 2.648.107 ₫
3.013.916 ₫ total
includes taxes & fees
14 Jul - 15 Jul
Tru By Hilton Cape Girardeau

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very good, (266)
"The facility was very nice. "
The price is 2.332.638 ₫
2.658.624 ₫ total
includes taxes & fees
27 Jul - 28 Jul
Comfort Inn & Suites Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (409)
"Overall a nice hotel, everything was clean and maintained, staff was helpful. We didn't realize there were no towels in the pool room til we were all wet, but made do with a couple from the gym next door😅 Breakfast was a great selection of hot and cold food options"
The price is 3.357.585 ₫
3.801.625 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Holiday Inn Express & Suites Sikeston Southwest by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Sikeston, MO

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Hotels with a pool in Sikeston you'll enjoy

These pet-friendly hotels in Sikeston may fit your trip

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

Photo by Ryan Coleman
Open Photo by Ryan Coleman

Frequently asked questions

What's the seasonal weather in Sikeston?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.