Sikeston Holidays
Book a Hotel + Flight or Car together to unlock savings
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Top hotels in Sikeston
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.364.037 ₫ per night from 14 Jan to 15 Jan
2.364.037 ₫
2.717.894 ₫ total
14 Jan - 15 Jan
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
The room was very nice and the bathroom was very clean. Everything was very nice and the breakfast was good. We were very pleased with everything. I recommend it highly.
Reviewed on 2 Jan 2026
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 2.689.785 ₫ per night from 25 Jan to 26 Jan
2.689.785 ₫
3.045.508 ₫ total
25 Jan - 26 Jan
includes taxes & fees
8.8/10 Excellent! (456 reviews)
We were stranded in Matthews, MO and this hotel was very accommodating to our situation. The staff were professional and friendly! The manager even had a staff member provide us with a ride to the nearest car rental place. The hotel was clean with great amenities! We even received a call after our ...
Reviewed on 30 Dec 2025
Best Western Plus Sikeston
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is 1.763.768 ₫ per night from 18 Jan to 19 Jan
1.763.768 ₫
2.010.253 ₫ total
18 Jan - 19 Jan
includes taxes & fees
8.2/10 Very Good! (1,006 reviews)
Everything was very good from entering to exiting.
Reviewed on 3 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Sikeston Depot Museum
You can spend time studying the exhibits at Sikeston Depot Museum during your travels in Sikeston. While in this relaxing area, you can savour the top-notch restaurants.
Central Park
Explore the great outdoors at Central Park, a lovely green space in Sikeston. While in this family-friendly area, you can savour the top-notch restaurants.
