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4 Jul - 5 Jul
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5 Jul - 6 Jul
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4 Jul - 6 Jul
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Top Trending Hotels Near South Main, Houston

Comfort Suites near Texas Medical Center - NRG Stadium
Lobby

Comfort Suites near Texas Medical Center - NRG Stadium

2.5 star property
8.6 out of 10, Excellent, (936)
"Great location close to nrg stadium rooms were good and breakfast was great"
The price is 2.566.688 ₫
3.003.024 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Comfort Suites near Texas Medical Center - NRG Stadium
Wyndham Houston near NRG Park/Medical Center
View from property

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1093)
"Perfect location to be walking distance to NRG. "
The price is 3.113.516 ₫
3.642.814 ₫ total
includes taxes & fees
15 Jul - 16 Jul
Wyndham Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.4 out of 10, (1004)
"Vanessa and everyone at front desk was extremely accommodating & gracious. The BEST out of the whole stay. Thank yall so much "
The price is 1.573.370 ₫
1.840.843 ₫ total
includes taxes & fees
4 Aug - 5 Aug
Quality Inn & Suites NRG Park - Medical Center
Wingate Houston near NRG Park/Medical Center
Room, 2 Double Beds, Non Smoking | 1 bedroom, desk, laptop workspace, blackout curtains

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (911)
"Great property "
The price is 2.331.889 ₫
2.728.310 ₫ total
includes taxes & fees
7 Jul - 8 Jul
Wingate Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (781)
"Convenient to where I wanted to be staff was nice too"
The price is 1.991.276 ₫
2.329.791 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Candlewood Suites Houston Medical Center by IHG
Hyatt Regency Houston/Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, pool loungers

Hyatt Regency Houston/Galleria

4.0 star property
8.8 out of 10, Excellent, (1004)
"It was a beautiful stay "
The price is 3.536.065 ₫
4.167.546 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Hyatt Regency Houston/Galleria
Hyatt Place Houston Medical Center
Lobby

Hyatt Place Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1760)
"totally recommend staying here! very nice, clean, safe place! "
The price is 3.379.929 ₫
3.975.477 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Hyatt Place Houston Medical Center
The Whitehall Houston
City view from property

The Whitehall Houston

4.0 star property
8.4 out of 10, Very good, (1559)
"Great hotel and location "
The price is 2.588.397 ₫
3.028.425 ₫ total
includes taxes & fees
3 Aug - 4 Aug
The Whitehall Houston
Omni Houston Hotel
Interior

Omni Houston Hotel

4.0 star property
9.0 out of 10, Wonderful, (1004)
"Would stay again ANY day!!"
The price is 4.239.846 ₫
5.035.030 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Omni Houston Hotel
The Lancaster Hotel
Exterior

The Lancaster Hotel

4.0 star property
9.6 out of 10, Exceptional, (1003)
"Wonderful hotel and great breakfast."
The price is 6.065.832 ₫
7.097.023 ₫ total
includes taxes & fees
5 Jul - 6 Jul
The Lancaster Hotel
Hyatt Regency Houston West
Terrace/patio

Hyatt Regency Houston West

3.5 star property
8.6 out of 10, Excellent, (1095)
"Great place "
The price is 3.375.156 ₫
3.948.933 ₫ total
includes taxes & fees
17 Jul - 18 Jul
Hyatt Regency Houston West
Blossom Hotel Houston
City view

Blossom Hotel Houston

4.0 star property
9.2 out of 10, Wonderful, (3374)
"We really enjoyed our stay "
The price is 3.961.591 ₫
4.635.061 ₫ total
includes taxes & fees
3 Aug - 4 Aug
Blossom Hotel Houston
Hyatt House Houston Medical Center
Lobby

Hyatt House Houston Medical Center

3.0 star property
9.2 out of 10, Wonderful, (1019)
"Lovely hotel"
The price is 3.636.796 ₫
4.277.603 ₫ total
includes taxes & fees
15 Jul - 16 Jul
Hyatt House Houston Medical Center
Haven Inn & Suites Downtown Houston
Premium bedding, desk, iron/ironing board, free WiFi

Haven Inn & Suites Downtown Houston

2.5 star property
9.4 out of 10, Exceptional, (1004)
"Nice place to stay"
Haven Inn & Suites Downtown Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Exterior detail

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4.0 star property
8.2 out of 10, Very good, (2161)
"Enjoyed my stay...the staff members are all super welcoming and accommodating "
The price is 2.591.436 ₫
3.053.203 ₫ total
includes taxes & fees
3 Aug - 4 Aug
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Holiday Inn Express & Suites Houston – Downtown North by IHG
Exterior

Holiday Inn Express & Suites Houston – Downtown North by IHG

2.5 star property
9.2 out of 10, Wonderful, (519)
"Very convenient location close to downtown very friendly staff, clean room I will recommend this hotel to my family "
The price is 2.799.548 ₫
3.275.472 ₫ total
includes taxes & fees
15 Jul - 16 Jul
Holiday Inn Express & Suites Houston – Downtown North by IHG
The Royal Sonesta Houston Galleria
Exterior

The Royal Sonesta Houston Galleria

4.0 star property
8.2 out of 10, Very good, (1092)
"Wonderful place "
The price is 3.077.307 ₫
4.274.864 ₫ total
includes taxes & fees
7 Jul - 8 Jul
The Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston
Lobby

Club Quarters Hotel Downtown, Houston

4.0 star property
8.4 out of 10, Very good, (3485)
"Comfortable, great staff and excellent restaurant on site."
The price is 2.672.502 ₫
3.126.829 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Club Quarters Hotel Downtown, Houston
La Quinta Inn & Suites by Wyndham Houston Southwest
Exterior

La Quinta Inn & Suites by Wyndham Houston Southwest

3.0 star property
6.8 out of 10, (1001)
"We loved the pool and the breakfast "
The price is 1.670.314 ₫
1.954.267 ₫ total
includes taxes & fees
7 Jul - 8 Jul
La Quinta Inn & Suites by Wyndham Houston Southwest
Sonesta ES Suites Houston Galleria
Lobby

Sonesta ES Suites Houston Galleria

3.0 star property
8.2 out of 10, Very good, (1048)
"I really enjoyed my stay. The bed was sooooo soft. The breakfast was pretty good as well. The employees at the front desk were so sweet. Great place to stay. "
The price is 2.566.688 ₫
3.003.104 ₫ total
includes taxes & fees
19 Jul - 20 Jul
Sonesta ES Suites Houston Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.
Discovery Green showing city views, modern architecture and a high-rise building
Downtown Houston map

Downtown Houston

3 out of top 10 points of interest in this area

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria map

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center map

Texas Medical Center

1 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection featuring interior views and art
Montrose map

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Houston which includes a skyscraper and a city
Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Frequently asked questions

What is South Main like?

You'll be sure to have fun exploring Houston's South Main neighbourhood. Consider a visit to NRG Park as part of your South Main travel plans.

How many hotels should I expect to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 62 South Main hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available in South Main.

What can I see and do in this Houston neighbourhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, make sure that you visit other sights such as NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.