Where to stay in South Main
Find the best South Main areas and neighborhoods for the activities you enjoy most. Learn more about South Main
Downtown Memphis
4 out of top 10 points of interest in this area
Downtown Memphis is a destination visitors seek out for its ample dining options, fascinating museums and great live music. You might also want to check out attractions like Statue of Elvis or Orpheum Theatre while you're exploring the neighbourhood.
East Memphis
2 out of top 10 points of interest in this area
Travellers to East Memphis praise its popular shops. If you've got some more time to explore, be sure to stop by Memphis Botanic Garden and Dixon Gallery and Gardens.
Midtown
1 out of top 10 points of interest in this area
Theatres, live music and museums are some highlights of Midtown. Make a stop by Minglewood Hall or Memphis Brooks Museum of Art while you're exploring.
Whitehaven
1 out of top 10 points of interest in this area
The ample dining options and great live music are top of the list for many visitors to Whitehaven. A stop by Graceland or Southland Mall might round out your trip.
Southwind
Southwind is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Mike Rose Soccer Complex or TPC Southwind.
Top hotels in South Main
ARRIVE Memphis
477 S Main St Memphis TN
Fully refundableReserve now, pay when you stay
3.782.035 ₫
4.543.333 ₫ total
13 Sept - 14 Sept
includes taxes & fees
9.6/10 Exceptional! (1,056 reviews)
"The elegance in the room. Clean room."
Reviewed on 28 Aug 2026
The Central Station Memphis, Curio Collection by Hilton
545 South Main Memphis TN
Fully refundableReserve now, pay when you stay
3.614.582 ₫
4.344.482 ₫ total
6 Sept - 7 Sept
includes taxes & fees
9/10 Wonderful! (1,001 reviews)
"Fabulous hotel with a very fun theme. Would stay again"
Reviewed on 28 Aug 2026
Hu. Hotel
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
1.890.804 ₫
2.353.626 ₫ total
27 Sept - 28 Sept
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a South Main holiday package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in South Main from just . And the more you bundle, the more you save. The getaway of your dreams has never been so affordable.
How do I get a cheap travel package to South Main?
Crafting your own South Main holiday package with Expedia is a great way to save. We have access to more than 550 airlines and 1null000null000 hotel options throughout the world. With such a fabulous range to select from, you'll have no worries pulling together your dream escape.
Where should I stay in South Main?
Make sightseeing easier by staying in a hotel just around the corner from South Main's terrific attractions. Graceland and Memphis Zoo are two traveller favourites.
What are the top hotels in South Main?
Sm 303 · Sophisticated Apartment With Historic Charm and Sm 204 · Historic Revival, Walking To Memphis' Best are two of the most well-known hotels in South Main. Why not check out the rates and amenities at each and then make a decision?
How far in advance should I book my South Main holiday?
Travellers are usually able to compare international flights on Expedia up to a year in advance of departure. Booking at the last minute? With a little bit of luck, it's still possible to nab a cheaper ticket only weeks before your journey.
What does an Expedia South Main travel package include?
Flights, hotels and a cool car for all your fun road trip adventures. Simply choose your preferred bundle and get access to incredible deals. Once you've made your booking, add on a few tours and experiences and watch your savings stack up. When it comes to organising your South Main trip, you're in control!
What should I know before booking a South Main travel package?
So many places to go, so many things to see and do. With a travel package, you'll be able to check more of them off your list. Bundle your hotels, rental cars and flights and score big savings.
Can I choose my airline with a South Main Expedia holiday package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to take your pick of available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my South Main holiday package?
We totally get it — sometimes life doesn't go according to plan. If you've booked a South Main holiday package and need to change or cancel it, we can help. We recommend taking a look at our Customer Service Portal first for information. But generally, if you've taken out your package within 24 hours, you may be able to cancel or change your itinerary at no cost. If it's been more than 24 hours, your airline, hotel or car rental company may impose a charge.
Stay near popular South Main attractions
Railroad & Trolley Museum
You can spend time exploring the galleries in Railroad & Trolley Museum in Memphis. Stroll along the riverfront or attend a sporting event in this romantic area.
Blues Hall of Fame Museum
You can spend an afternoon browsing the exhibits at Blues Hall of Fame Museum during your trip to Memphis. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.