Search Hotels in South Main, Memphis

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14 Dec - 15 Dec
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Our top choices for South Main hotels

Exterior
The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton
4.0 star property
South Main
9.0 out of 10, Wonderful, (1004)
"Wonderful staff and ambiance "
United States
Gabriela
The price is 2.939.807 ₫
3.543.636 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Central Station Memphis, Curio Collection by Hilton
Egyptian cotton sheets, premium bedding, pillow-top beds, minibar
ARRIVE Memphis

ARRIVE Memphis

ARRIVE Memphis
4.0 star property
South Main
9.6 out of 10, Exceptional, (1001)
"Great stay "
United States
LaKera
The price is 4.603.725 ₫
5.519.735 ₫ total
includes taxes & fees
25 Dec - 26 Dec
ARRIVE Memphis
Grand Suite | Premium bedding, minibar, blackout curtains, iron/ironing board
Hotel Pontotoc

Hotel Pontotoc

Hotel Pontotoc
2.0 star property
South Main
10.0 out of 10, Exceptional, (2)
"Beautiful hotel, great bar, spacious rooms. Excellent!!!"
United States
Cheryl
The price is 5.498.163 ₫
6.529.069 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Pontotoc
Luxury Penthouse, 6 Bedrooms | Individually decorated, individually furnished, laptop workspace
The Rambler

The Rambler

The Rambler
4.0 star property
South Main
9.2 out of 10, Wonderful, (523)
"Walkable, neat spot."
United States
Teresa
The price is 3.473.787 ₫
4.177.735 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Rambler
Exterior
Hampton Inn & Suites Memphis-Beale Street

Hampton Inn & Suites Memphis-Beale Street

Hampton Inn & Suites Memphis-Beale Street
2.5 star property
Downtown Memphis, 0.9 km from South Main
8.6 out of 10, Excellent, (1230)
"Excellent hotel in a great location "
United States
Ralph
The price is 2.925.338 ₫
3.526.453 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Memphis-Beale Street
Lunch and dinner served, American cuisine
Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria
3.0 star property
Wolfchase, 24.7 km from South Main
9.0 out of 10, Wonderful, (1370)
"Great place, clean, friendly, accommodating."
United States
MaryAnn
The price is 2.446.551 ₫
2.957.893 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Place Memphis/Wolfchase Galleria
Seasonal outdoor pool
Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown
2.5 star property
Downtown Memphis, 1.6 km from South Main
8.8 out of 10, Excellent, (1007)
"Great hotel "
United States
Andre
The price is 2.261.810 ₫
2.738.515 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn Memphis Downtown
Reception
La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland
3.0 star property
8.8 km from South Main
7.4 out of 10, Good, (2206)
"Room was clean the stay was very pleasant"
United States
Tammy
The price is 1.319.296 ₫
1.619.279 ₫ total
includes taxes & fees
21 Dec - 22 Dec
La Quinta Inn & Suites by Wyndham Memphis Airport Graceland
Food and drink
Hu. Hotel

Hu. Hotel

Hu. Hotel
3.5 star property
Downtown Memphis, 1.3 km from South Main
8.4 out of 10, Very good, (1618)
"Great hotel and location "
United States
Holiday
The price is 2.307.650 ₫
2.861.458 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hu. Hotel
Hypo-allergenic bedding, pillow-top beds, minibar, in-room safe
The Westin Memphis Beale Street

The Westin Memphis Beale Street

The Westin Memphis Beale Street
4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1003)
"Room and location was very nice. "
United States
DEREX
The price is 4.235.427 ₫
5.082.183 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin Memphis Beale Street
Exterior
Big Cypress Lodge

Big Cypress Lodge

Big Cypress Lodge
5.0 star property
Pinch District, 2.3 km from South Main
9.0 out of 10, Wonderful, (1714)
"The lodge was amazing, we will be back soon."
United States
Carl
The price is 6.024.303 ₫
7.732.613 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Big Cypress Lodge
View from property
Residence Inn by Marriott Memphis Downtown

Residence Inn by Marriott Memphis Downtown

Residence Inn by Marriott Memphis Downtown
3.0 star property
Downtown Memphis, 1.2 km from South Main
9.2 out of 10, Wonderful, (897)
"Friendly staff, well kept and comfortable rooms. "
United States
Joanne
The price is 3.172.624 ₫
3.820.105 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Residence Inn by Marriott Memphis Downtown
Terrace/patio
Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis
4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1403)
"Amazing hotel and staff and very convenient location to restaurants and shopping. "
United States
Timothy
The price is 3.527.769 ₫
4.241.839 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Centric Beale Street Memphis
4 bars/lounges
Southland Casino Hotel

Southland Casino Hotel

Southland Casino Hotel
3.0 star property
9.7 km from South Main
8.8 out of 10, Excellent, (1758)
"Super friendly, love this hotel!"
United States
Dave
The price is 3.130.533 ₫
3.615.897 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Southland Casino Hotel
Exterior
Hampton Inn & Suites Memphis-Wolfchase Galleria

Hampton Inn & Suites Memphis-Wolfchase Galleria

Hampton Inn & Suites Memphis-Wolfchase Galleria
2.5 star property
Wolfchase, 25.3 km from South Main
8.8 out of 10, Excellent, (851)
"I loved my stay"
United States
beatrice
The price is 2.441.290 ₫
2.923.444 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Hampton Inn & Suites Memphis-Wolfchase Galleria
Exterior
Holiday Inn Express & Suites Memphis Arpt Elvis Presley Blv by IHG

Holiday Inn Express & Suites Memphis Arpt Elvis Presley Blv by IHG

Holiday Inn Express & Suites Memphis Arpt Elvis Presley Blv by IHG
2.5 star property
Whitehaven, 9.2 km from South Main
8.2 out of 10, Very good, (1002)
"Clean, quiet, modern, and wonderful staff."
United States
Rebecca
The price is 2.657.007 ₫
3.207.809 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Memphis Arpt Elvis Presley Blv by IHG
Bar (on property)
Canopy by Hilton Memphis Downtown

Canopy by Hilton Memphis Downtown

Canopy by Hilton Memphis Downtown
4.0 star property
Downtown Memphis, 1.1 km from South Main
8.6 out of 10, Excellent, (1002)
"Courteous staff, great location and walking distance to everything. Wining and dining. Food and ambience are superb. "
United States
Dennis
The price is 3.020.044 ₫
3.638.917 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Canopy by Hilton Memphis Downtown
Exterior
La Quinta Inn & Suites by Wyndham West Memphis

La Quinta Inn & Suites by Wyndham West Memphis

La Quinta Inn & Suites by Wyndham West Memphis
3.0 star property
11.3 km from South Main
8.6 out of 10, Excellent, (1004)
"The staff was super friendly!! Room was clean and breakfast was great!"
United States
Sheri
The price is 2.146.651 ₫
2.479.380 ₫ total
includes taxes & fees
16 Dec - 17 Dec
La Quinta Inn & Suites by Wyndham West Memphis
Lobby lounge
Memphis Vitality Hotel

Memphis Vitality Hotel

Memphis Vitality Hotel
4.0 star property
15.5 km from South Main
8.4 out of 10, Very good, (1198)
"Excellent trip"
United States
Mubeen
The price is 2.059.838 ₫
2.498.672 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Memphis Vitality Hotel
Lobby
Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven
3.0 star property
19.9 km from South Main
9.2 out of 10, Wonderful, (1006)
"Friendly staff, clean room, happy hour food & drink"
United States
Kathleen
The price is 2.630.437 ₫
2.919.814 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Drury Inn & Suites Memphis Southaven
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.

Downtown Memphis

Downtown Memphis is a destination visitors seek out for its ample dining options, fascinating museums and great live music. You might also want to check out attractions like Statue of Elvis or Orpheum Theatre while you're exploring the neighbourhood.

East Memphis

Travellers to East Memphis praise its popular shops. If you've got some more time to explore, be sure to stop by Leftwich Tennis Center and Theatre Memphis.

Midtown

Theatres, live music and museums are some highlights of Midtown. Make a stop by Minglewood Hall or Memphis Brooks Museum of Art while you're exploring.

Whitehaven

The ample dining options and great live music are top of the list for many visitors to Whitehaven. A stop by Graceland or Tri-State Bank of Memphis might round out your trip.

North Memphis

Visitors to North Memphis like its bars and churches, and Burkle Estate is a sight worth a stop.

Top South Main Hotel Reviews

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Frequently asked questions

What is South Main like?
You'll be sure to have fun exploring Memphis's South Main neighbourhood. Make sure that you visit Blues Hall of Fame Museum and Railroad & Trolley Museum as part of your South Main travel plans.
How many hotels can I expect to find in South Main?
Expedia has 47 hotels and other accommodation options in South Main to choose from, making this an ideal home base for exploring the greater Memphis area.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals available in South Main.
What are the top things to see and do in South Main?
Create some family memories with a visit to Blues Hall of Fame Museum or Railroad & Trolley Museum while you're in South Main. When you're sightseeing in Memphis, National Civil Rights Museum and Lorraine Motel are also worth a stop.
How can I get around South Main and the greater Memphis area?
To venture out of town, take a train from Memphis Central Station.