Search Hotels Near South Mississippi County Regional Medical Center, Osceola

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
19 Dec - 20 Dec
Tomorrow
20 Dec - 21 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Mississippi County Regional Medical Center hotels

Luxury Cottage, 3 Bedrooms | Private kitchen | Mini-fridge, coffee/tea maker
The Louis Hotel

The Louis Hotel

The Louis Hotel
4.0 star property
15.7 km from South Mississippi County Regional Medical Center
9.6 out of 10, Exceptional, (48)
"Beautiful property and very attentive staff-not much to do in this quaint little village, but that's exactly what we wanted. Walked to the cafe for dinner, nightcaps at the hotel bar (beautiful), had a great restful nights sleep, and then we walked back to the cafe for a wonderful brunch the next morning. The town is an oasis in the middle of nowhere!"
United States
David
The price is 5.773.511 ₫
6.466.385 ₫ total
includes taxes & fees
20 Jan - 21 Jan 2026
The Louis Hotel
Seasonal outdoor pool
Holiday Inn Osceola by IHG

Holiday Inn Osceola by IHG

Holiday Inn Osceola by IHG
3.0 star property
6.4 km from South Mississippi County Regional Medical Center
8.8 out of 10, Excellent, (14)
"The hotel was perfect for our two night stay while we were moving. There is a restaurant connected to the hotel that provided a nice buffet breakfast. The beds were very comfortable. "
United States
Cynthia Beth
The price is 2.999.910 ₫
3.464.896 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Osceola by IHG
Lobby
Days Inn & Suites by Wyndham Osceola AR

Days Inn & Suites by Wyndham Osceola AR

Days Inn & Suites by Wyndham Osceola AR
2.0 star property
6.1 km from South Mississippi County Regional Medical Center
6.4 out of 10, (365)
"The staff was very helpful and friendly. "
United States
Neil
The price is 1.683.897 ₫
1.944.902 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Days Inn & Suites by Wyndham Osceola AR
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top South Mississippi County Regional Medical Center Hotel Reviews

Deerfield Inn By Capital O Blytheville AR I55

Deerfield Inn By Capital O Blytheville AR I55

10/10 Excellent
"The front desk worker went outta hee way to make sure i had everything i needed and was so kind "
melissa 1-night trip
Posted 2 months ago
Deerfield Inn By Capital O Blytheville AR I55
Holiday Inn Osceola by IHG

Holiday Inn Osceola by IHG

10/10 Excellent
"Comfy "
James 1-night trip
Posted 3 months ago
Holiday Inn Osceola by IHG

Hotels near other South Mississippi County Regional Medical Center attractions

Florida Park

Florida Park is just one of the places to see in Osceola, so why not enjoy the other things to explore during your travels? You can enjoy the restaurants while in the area.
See properties

Osceola Branch Mississippi County Library

After visiting Osceola Branch Mississippi County Library, make a plan to see the other sights and activities in Osceola. You can enjoy the restaurants while in the area.
See properties

Frequently asked questions

What's the area like around South Mississippi County Regional Medical Center?
South Mississippi County Regional Medical Center is located in Osceola. Travellers like this welcoming area for its restaurants. If you're looking for a convenient place to stay, take a look at the 6 hotels and other accommodation options you'll find within a mile.
How many hotels will I find close to South Mississippi County Regional Medical Center?
Expedia has 6 hotels and other accommodation options within a mile from South Mississippi County Regional Medical Center.
If I need to cancel the hotel reservation for my stay near South Mississippi County Regional Medical Center, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to review the top deals on offer near South Mississippi County Regional Medical Center.