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Check availability on South Yarmouth Business Hotels

Our top choices for South Yarmouth business-friendly hotels

Fitness facility
All Seasons Resort, Trademark Collection by Wyndham

All Seasons Resort, Trademark Collection by Wyndham

All Seasons Resort, Trademark Collection by Wyndham
3.0 star property
Bass River
8.4 out of 10, Very good, (304)
"My room was very clean. The staff were friendly."
United States
Shanique
The price is 2.373.300 ₫
3.078.434 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
All Seasons Resort, Trademark Collection by Wyndham
Fridge, microwave, oven, stovetop
Thompson House Cape Cod

Thompson House Cape Cod

Thompson House Cape Cod
3.0 star property
South Yarmouth
The price is 10.679.850 ₫
33.107.799 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Thompson House Cape Cod
Exterior
Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth

Aiden by Best Western Cape Cod - West Yarmouth
3.0 star property
West Yarmouth
8.0 out of 10, Very good, (1001)
"Nice place and good options for breakfast "
United States
Jennifer
The price is 2.554.741 ₫
2.923.901 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Aiden by Best Western Cape Cod - West Yarmouth
Lobby lounge
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
2.5 star property
Hyannis
8.8 out of 10, Excellent, (656)
"Great people, nice breakfast "
United States
Lorri
The price is 2.662.562 ₫
3.047.302 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Terrace/patio
The Mansion at Ocean Edge

The Mansion at Ocean Edge

The Mansion at Ocean Edge
4.0 star property
Brewster
8.2 out of 10, Very good, (1002)
"Amazing stay and location! "
United States
Joanne
The price is 4.309.705 ₫
6.441.154 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Mansion at Ocean Edge
Indoor pool, open 8:00 AM to 10:00 PM, pool loungers
The Mariner Resort Cape Cod by The Red Collection

The Mariner Resort Cape Cod by The Red Collection

The Mariner Resort Cape Cod by The Red Collection
3.0 star property
West Yarmouth
8.0 out of 10, Very good, (432)
"Great proximity to quick shopping and restaurants/coffee"
United States
Theodore
The price is 2.071.412 ₫
2.634.350 ₫ total
includes taxes & fees
16 Dec - 17 Dec
The Mariner Resort Cape Cod by The Red Collection
Indoor pool
Courtyard Resort

Courtyard Resort

Courtyard Resort
2.0 star property
Hyannis
8.2 out of 10, Very good, (43)
"Room was very clean. Staff were courteous!"
United States
Timothy
The price is 2.874.330 ₫
3.289.670 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Courtyard Resort
Free daily continental breakfast
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
Hyannis
8.0 out of 10, Very good, (1000)
"Well appointed lodging with very friendly and attentive staff. Perfect central location with easy walk to many local sights as well as convenient access to ferry terminal. "
United States
Kerri
The price is 2.586.112 ₫
2.959.806 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Comfort Inn Hyannis - Cape Cod
Front of property
Hyannis Harbor Hotel

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
Hyannis
8.0 out of 10, Very good, (1003)
"Amazing place "
United States
Mounir
The price is 3.294.932 ₫
4.835.870 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Hyannis Harbor Hotel
Indoor pool, seasonal outdoor pool
Four Points by Sheraton Eastham Cape Cod

Four Points by Sheraton Eastham Cape Cod

Four Points by Sheraton Eastham Cape Cod
3.0 star property
Eastham
8.2 out of 10, Very good, (856)
"Perfect overnight stay in every way!"
United States
Debra
The price is 3.111.660 ₫
3.561.295 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Four Points by Sheraton Eastham Cape Cod
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Yarmouth Hotel Reviews

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Frequently asked questions

How much do business-friendly hotels in South Yarmouth cost?
Rates for business hotels in South Yarmouth range between 2.634.350 ₫ and 33.107.799 ₫ per night. No matter your budget, Expedia will help you locate the ideal space for a successful work trip. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in South Yarmouth?
Pick from multiple business-friendly hotels in South Yarmouth that have a total average guest review rating of 8.1. Sesuit Harbour House is a hit among corporate travellers. This 3-stars property comes with amenities such as a barbecue grill and a firepit. The Escape Inn is another sought-after option. It has a 2.5-stars rating and conveniences including pool sun loungers and a swimming pool.
How many business-friendly hotels are there in South Yarmouth?
South Yarmouth has 13 hotels that accommodate business travellers. Whether you're seeking a location close to the city centre or amenities like dependable WiFi and conference rooms, you'll find everything you need with Expedia.
What are the best cheap business-friendly hotels in South Yarmouth?
The Escape Inn is a great pick for corporate travellers in search of a money-saving option. It features amenities like a garden and pool sun loungers. Another budget stay for a work-related trip is Hampton Inn & Suites Cape Cod-West Yarmouth. Pool sun loungers and a swimming pool are two of the conveniences here. Rates for business-friendly hotels in South Yarmouth start at 2.634.350 ₫ per night, so you'll have cash left over to spend on post-meeting entertainment. When it's time to explore South Yarmouth, add some terrific free attractions to your work travel plans. West Dennis Beach and Mayflower Beach are great ways to spend a day. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in South Yarmouth?
A Beach Breeze Inn is a top choice for corporate travellers in search of affordability and comfort. Located around 8 km east of downtown South Yarmouth, a swimming pool and a barbecue grill are among its many amenities. Or settle in and make deals on the road at Chatham Tides. This business-friendly property offers conveniences like hypo-allergenic bedding and a nearby waterfront and is approximately 14 km east of central South Yarmouth.There are so many things to do and see around South Yarmouth. Take time out from your business meetings to visit top attractions like West Dennis Beach and Cape Codder Water Park.
Are there any family-friendly hotels in South Yarmouth that are also business friendly?
If you're planning a family trip to South Yarmouth but still have to work, consider Sesuit Harbour House. This 3-stars retreat features handy amenities like a playground and a children's pool. Riverview Resort By Vri Americas is another property that's ideal for both leisure and business guests. It has a 3-stars rating and conveniences such as a playground and WiFi. Of course, work shouldn't take up all of your time in South Yarmouth! Round up the kids and explore top family-friendly attractions, such as West Dennis Beach and Cape Codder Water Park.
Why book your business-friendly hotel in South Yarmouth with Expedia?
With useful amenities like conference rooms, laundry facilities and free WiFi, our business-friendly properties come with everything you'll need to settle that big contract — and then put your feet up! Enter your preferred travel dates and destination and Expedia will help you plan everything else.
How can I find cheap business-friendly hotels in South Yarmouth?
Select the "business friendly" filter, listed under the "traveller experience" heading, to find cheap business-friendly hotels in South Yarmouth. Then narrow your search by your nightly budget. Looking for stays in a less popular neighbourhood is another easy way to save.
What is there to do in South Yarmouth near my business-friendly hotel?
South Yarmouth has enough activities and sights to keep you going for weeks, beginning with West Dennis Beach. Cape Codder Water Park, Mayflower Beach and Cape Cod Inflatable Park are other impressive attractions. If your business trip keeps you hanging around town a little longer, Craigville Beach and Seagull Beach are worthwhile additions to your itinerary.