Find hotels in Southern Illinois, IL from 1.283.820 ₫

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southern Illinois hotels

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean rooms, great food, friendly staff"
United States
John
The price is 1.707.417 ₫
2.048.690 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Drury Inn & Suites Marion

Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG
2.5 star property
Effingham
9.4 out of 10, Exceptional, (1,005 reviews)
"Everything was great the gentleman that checked us in was awesome and the rooms are clean and a great size "
United States
Kristen
The price is 2.311.936 ₫
2.588.843 ₫ total
includes taxes & fees
6 Feb - 7 Feb
Holiday Inn Express & Suites Effingham by IHG

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,627 reviews)
"Clean nice people great place to stay"
United States
John
The price is 2.915.929 ₫
3.288.641 ₫ total
includes taxes & fees
23 Jan - 24 Jan
Drury Plaza Hotel Mt. Vernon

Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (702 reviews)
"Very clean, nice hot breakfast, and kind staff. "
United States
Erin
The price is 2.779.052 ₫
3.084.193 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn & Suites Effingham

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,008 reviews)
"It's great for travelers!"
United States
Kerry
The price is 3.060.425 ₫
3.448.988 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Comfort Suites Mount Vernon

Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24
2.5 star property
Metropolis
8.0 out of 10, Very good, (1,000 reviews)
"Courteous staff, clean rooms. "
United States
Jennifer
The price is 1.363.254 ₫
1.591.492 ₫ total
includes taxes & fees
15 Feb - 16 Feb
Quality Inn & Suites Metropolis I-24

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,002 reviews)
"The staff were friendly and welcoming.the room was perfect. Enjoyed our stay."
United States
Patricia Mahoney
The price is 2.434.101 ₫
2.725.705 ₫ total
includes taxes & fees
25 Jan - 26 Jan
La Quinta Inn & Suites by Wyndham Effingham

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
3.5 star property
Metropolis
8.2 out of 10, Very good, (1,001 reviews)
"Great hotel. Clean and friendly staff! "
United States
Robin
The price is 2.695.573 ₫
3.411.899 ₫ total
includes taxes & fees
17 Feb - 18 Feb
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Baymont by Wyndham Effingham

Baymont by Wyndham Effingham
2.5 star property
Effingham
8.0 out of 10, Very good, (1,004 reviews)
"Great room! The staff was super nice!"
United States
James
The price is 1.786.496 ₫
1.982.654 ₫ total
includes taxes & fees
6 Feb - 7 Feb
Baymont by Wyndham Effingham

Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.8 out of 10, Excellent, (1,000 reviews)
"Clean room, friendly check-in "
United States
Shelley
The price is 2.344.776 ₫
2.602.232 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Country Inn & Suites by Radisson, Effingham, IL

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (923 reviews)
"Great place to stay."
United States
Stephen
The price is 1.891.321 ₫
2.098.989 ₫ total
includes taxes & fees
28 Jan - 29 Jan
SureStay Hotel by Best Western Whittington Rend Lake

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG
2.5 star property
Marion
9.0 out of 10, Wonderful, (937 reviews)
"Great stay"
United States
Charles
The price is 2.338.208 ₫
2.805.383 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
Edwardsville
8.6 out of 10, Excellent, (657 reviews)
"The room was very clean and the staff is always friendly "
United States
Lynn
The price is 2.390.752 ₫
2.748.839 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Country Hearth Inn & Suites Edwardsville St. Louis

Best Western Delta Inn

Best Western Delta Inn
2.5 star property
Effingham
9.2 out of 10, Wonderful, (1,007 reviews)
"Staff very friendly!"
United States
C. Mark
The price is 2.210.789 ₫
2.475.641 ₫ total
includes taxes & fees
10 Feb - 11 Feb
Best Western Delta Inn

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (815 reviews)
"Very Clean, big bed. Would stay again, just know you definitely hear the highway all night."
United States
Amanda
The price is 1.786.496 ₫
1.947.018 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Ramada by Wyndham Vandalia

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very good, (1,004 reviews)
"Consistently nice place"
United States
Cindy
The price is 1.663.018 ₫
1.812.506 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Home2 Suites By Hilton Effingham

Home2 Suites By Hilton Effingham
3.0 star property
Effingham
9.6 out of 10, Exceptional, (33 reviews)
"Very kind staff, very clean, very pleased. "
United States
Erin
The price is 2.779.052 ₫
3.111.984 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Home2 Suites By Hilton Effingham

Quality Inn Effingham North

Quality Inn Effingham North
2.5 star property
Effingham
8.4 out of 10, Very good, (1,003 reviews)
"It’s a good place to stay for a reasonable price."
United States
Brenda
The price is 2.009.808 ₫
2.230.485 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Quality Inn Effingham North

Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1,001 reviews)
"Easy check-in. Good rate and dog friendly at a good fee"
United States
Curt
The price is 1.749.715 ₫
1.994.307 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Super 8 by Wyndham Mt. Vernon IL

The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.8 out of 10, Exceptional, (199 reviews)
"Comfortable, interesting concept, great restaurant"
United States
Nancy
The price is 2.963.744 ₫
3.289.254 ₫ total
includes taxes & fees
20 Jan - 21 Jan
The Principal Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Rentals in Southern Illinois

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southern Illinois attractions

Learn more about Southern Illinois

Experience the family-friendly area of Southern Illinois—live music, an opera house and sights from Jefferson County Fairgrounds to Salem Fairgrounds.

Southern Illinois featuring landscape views, a sunset and forest scenes
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

More cheap stays in Southern Illinois

Hotels in Southern Illinois with star rating