Southern Illinois Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
Where to stay in Southern Illinois
Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Eastport
While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.
Top hotels in Southern Illinois
Drury Plaza Hotel Mt. Vernon
145 North 44th Street Mount Vernon IL
Fully refundableReserve now, pay when you stay
The price is 3.393.727 ₫ per night from 4 Jul to 5 Jul
3.393.727 ₫
3.818.979 ₫ total
4 Jul - 5 Jul
includes taxes & fees
9.6/10 Exceptional! (1,728 reviews)
"Staff was very pleasant, our room was very nice and entire hotel was clean, shiny and classy!"
Reviewed on 11 Jun 2026
Drury Inn & Suites St. Louis Fairview Heights
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
The price is 2.788.597 ₫ per night from 5 Jul to 6 Jul
2.788.597 ₫
3.150.556 ₫ total
5 Jul - 6 Jul
includes taxes & fees
9.2/10 Wonderful! (1,019 reviews)
"Great place to stay! And, their breakfast is great too!"
Reviewed on 13 Jun 2026
Baymont by Wyndham Effingham
1811 W Fayette Avenue Effingham IL
Fully refundableReserve now, pay when you stay
The price is 2.124.533 ₫ per night from 2 Jul to 3 Jul
2.124.533 ₫
2.357.807 ₫ total
2 Jul - 3 Jul
includes taxes & fees
8.2/10 Very Good! (1,002 reviews)
"We had a booking issue. Accidentally booked the room for the wrong date. We needed a room at 12:30am at night - last minute - to stop on our way to our destination. The room was accidentally reserved for the following day. I contacted support immediately. Less than a minute after confirming and realizing ..."
Reviewed on 8 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
