Southern Illinois Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Southernmost Illinois Tourism Bureau

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
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Eastport

While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.

Find hotels in Eastport

Top hotels in Southern Illinois

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is 2.504.859 ₫ per night from 27 Jul to 28 Jul
2.504.859 ₫
2.832.082 ₫ total
27 Jul - 28 Jul
includes taxes & fees
9.6/10 Exceptional! (1,365 reviews)
"A clean room and a helpful staff!"

Reviewed on 29 Jun 2025

Drury Plaza Hotel Mt. Vernon
Best Western Plus Pontoon Beach
Best Western Plus Pontoon Beach
3 out of 5
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is 2.325.325 ₫ per night from 2 Jul to 3 Jul
2.325.325 ₫
2.580.647 ₫ total
2 Jul - 3 Jul
includes taxes & fees
8.4/10 Very Good! (679 reviews)
"Super easy to access the rooms, ample door parking, friendly staff, super clean, breakfast was good-made my kids happy! The citrus shampoo, conditioner and body wash the hotel provided smelled SO GOOD! Overall, excellent stay."

Reviewed on 30 Jun 2025

Best Western Plus Pontoon Beach
Days Inn & Suites by Wyndham Caseyville
Days Inn & Suites by Wyndham Caseyville
2.5 out of 5
2423 Old Country Inn Drive, Caseyville, IL
Fully refundableReserve now, pay when you stay
The price is 1.385.644 ₫ per night from 13 Jul to 14 Jul
1.385.644 ₫
1.563.882 ₫ total
13 Jul - 14 Jul
includes taxes & fees
3.8/10 (238 reviews)
"Pet Friendly"

Reviewed on 9 Jun 2025

Days Inn & Suites by Wyndham Caseyville
See all 1,031 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southern Illinois holiday package cost?
From just , you can tailor make your Southern Illinois holiday package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1null000null000 hotels globally, your Southern Illinois holiday package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It's an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for lots of travellers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois holiday?
Reward yourself with the widest variety at the lowest prices by booking your holiday to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it's never a bad time to book your dream holiday!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you're contemplating. Southern Illinois holiday deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You'll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you're organising a ritzy city getaway or a low-cost family road trip, explore our holiday packages today.
Can I choose my airline with a Southern Illinois Expedia holiday package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois holiday package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Popular places to visit

Southern Illinois University

Southern Illinois University

Enjoy the student vibe when you visit Southern Illinois University during your trip to Carbondale. Visit the shops and top-notch restaurants in this family-friendly area.

Southern Illinois University
Garden of the Gods Recreation Area

Garden of the Gods Recreation Area

Explore the great outdoors at Garden of the Gods Recreation Area, a lovely green space in Equality. While you're in the area, stroll along the riverfront.

Garden of the Gods Recreation Area
Cahokia Mounds State Historic Site

Cahokia Mounds State Historic Site

You can learn about the history of Collinsville with a trip to Cahokia Mounds State Historic Site. Discover the great live music in this walkable area or seek out the local tours.

Cahokia Mounds State Historic Site