Find hotels in Southern Minnesota, MN from 1.700.857 ₫

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9 Dec - 10 Dec
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10 Dec - 11 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for Southern Minnesota hotels

Front of property – evening/night
Kahler Grand Hotel

Kahler Grand Hotel

3.0 star property
Downtown Rochester
8.4 out of 10, Very good, (1814)
"Staff was friendly and helpful! Will continue to stay here while at the Mayo, "
United States
Gayle
The price is 3.535.144 ₫
4.069.835 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Kahler Grand Hotel
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (884)
"Great room and stay!"
United States
Trevor
The price is 1.818.978 ₫
2.094.197 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Serves lunch, dinner and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
Rochester
8.2 out of 10, Very good, (1130)
"Great location and value"
United States
Michelle
The price is 1.923.899 ₫
2.214.889 ₫ total
includes taxes & fees
13 Dec - 14 Dec
AmericInn by Wyndham Rochester Near Mayo Clinic
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
Rochester
7.2 out of 10, Good, (1020)
"Great value for the price. "
United States
Beth Anne
The price is 1.898.064 ₫
2.185.146 ₫ total
includes taxes & fees
12 Dec - 13 Dec
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (956)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is 2.666.516 ₫
3.122.551 ₫ total
includes taxes & fees
12 Dec - 13 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
BBQ/picnic Area
Aspen Suites

Aspen Suites

3.0 star property
Rochester
9.0 out of 10, Wonderful, (686)
"I always stay at this hotel , love it clean comfortable rooms, they gave us vouchers for 4 free meals for Thanksgiving dinner"
United States
Cindy
The price is 4.085.846 ₫
4.938.920 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Aspen Suites
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

2.0 star property
Rochester
9.0 out of 10, Wonderful, (894)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is 1.658.170 ₫
1.908.967 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Econo Lodge Mayo Clinic Area
Property entrance
Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic

3.0 star property
Rochester
8.4 out of 10, Very good, (1006)
"Clean room, fun staff."
United States
Thomas
The price is 2.554.478 ₫
2.940.842 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Country Inn & Suites Rochester South Mayo Clinic
Exterior
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3.0 star property
Rochester
9.4 out of 10, Exceptional, (305)
"The rooms are very nice and the staff is very friendly "
United States
Roberta
The price is 1.813.706 ₫
2.088.134 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Spark by Hilton Rochester South
Exterior
AmericInn by Wyndham Winona

AmericInn by Wyndham Winona

2.5 star property
Winona
9.0 out of 10, Wonderful, (892)
"Nice time with clean accomodations and friendly staff. Will stay there again. "
United States
JEANETTE
The price is 2.823.370 ₫
3.151.585 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
AmericInn by Wyndham Winona
Lobby
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (541)
"Had a great stay. Room was very clean and staff was very courteous. "
United States
Bonita
The price is 4.517.920 ₫
5.201.255 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Hilton Rochester Mayo Clinic Area
In-room safe, desk, iron/ironing board, free cots/infant beds
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
Rochester
7.8 out of 10, Good, (1000)
"Front staff are so kind and efficient. "
United States
Brenda
The price is 1.613.354 ₫
1.857.373 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
Desk, iron/ironing board, free WiFi, bed sheets
Brentwood Inn & Suites

Brentwood Inn & Suites

2.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1000)
"Room was clean breakfast was good everybody was helpful "
United States
james
The price is 2.965.725 ₫
3.414.143 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Brentwood Inn & Suites
Exterior
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3.0 star property
Kutzky Park
8.6 out of 10, Excellent, (933)
"Room was comfortable and convenient.Staff was exceptional.I will stay here when I am next in town."
United States
Rachel
The price is 2.478.028 ₫
2.852.829 ₫ total
includes taxes & fees
19 Dec - 20 Dec
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Lunch and dinner served, American cuisine
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1003)
"The room was clean, the staff was very friendly and helpful."
United States
kenneth
The price is 3.247.798 ₫
3.738.922 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lunch and dinner served, American cuisine
The Plaza Hotel & Suites Winona

The Plaza Hotel & Suites Winona

3.0 star property
Winona
8.8 out of 10, Excellent, (1004)
"The pools were great"
United States
Beth
The price is 3.163.440 ₫
3.531.190 ₫ total
includes taxes & fees
11 Dec - 12 Dec
The Plaza Hotel & Suites Winona
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room) | Blackout curtains, soundproofing, iron/ironing board, rollaway beds
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
Rochester
8.2 out of 10, Very good, (783)
"Great place to stay. Freindly staff"
United States
joel
The price is 2.479.082 ₫
2.854.044 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2 indoor pools
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 star property
Kutzky Park
7.8 out of 10, Good, (1011)
"Room was clean, great location, convenient to restaurant. "
United States
Sam
The price is 1.900.436 ₫
2.187.878 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Med City Inn & Suites - Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (1006)
"Great location. Friendly staff. Easy access to Mayo Clinic’s via shuttle. Rooms were comfortable and spacious. "
United States
Jill
The price is 3.400.698 ₫
3.915.053 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hyatt House Rochester/Mayo Clinic Area
Exterior
Aspen Select

Aspen Select

3.5 star property
Rochester
8.4 out of 10, Very good, (1001)
"Front desk staff was amazing, room was clean and the bed was comfortable! Location was perfect for us, right across the street from the hospital. Will definitely stay again, if the need arises! "
United States
Dana
Aspen Select
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southern Minnesota, MN

Showing deals for:19 Dec - 21 Dec

Image gallery for The Towers At Kahler Grand Hotel

Front of property

The Towers At Kahler Grand Hotel

4.0 star property
Rochester
9.4/10Exceptional (94 reviews)
10% off
Price is 10.893.447 ₫
25.082.162 ₫ total
includes taxes & fees
The Towers At Kahler Grand Hotel
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Stay near popular Central United States attractions

Lake Shetek State Park

4.4/5 (5 reviews)
Commune with nature and explore the great outdoors at Lake Shetek State Park during your travels in The Lakes. Amble around the area's parks or experience its museums.
See properties

Mayo Civic Center

4.5/5 (411 reviews)
Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops.
See properties

Learn more about Southern Minnesota

Explore the family-friendly area of Southern Minnesota—an opera house, shopping and sights from Mount Kato Ski Area to Blakeslee Stadium.

See all hotels in Southern Minnesota
Lake Pepin & Mississippi River Scenic View

Top Southern Minnesota Hotel Reviews

More cheap stays in Southern Minnesota

Hampton Inn Rochester-South

Hampton Inn Rochester-South

1755 S Broadway Rochester MN
The price is 2.168.602 ₫ per night from 4 Jan to 5 Jan
2.168.602 ₫
2.496.603 ₫ total
4 Jan - 5 Jan 2026
includes taxes & fees
9/10 Wonderful! (1,008 reviews)

Hotels in Southern Minnesota with star rating

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