Search Hotels in Southhampton, St. Louis

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southhampton hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
8.4 out of 10, Very good, (4,031 reviews)
"Room was clean, excellent view!"
United States
Jennifer
The price is 3.285.250 ₫
3.874.262 ₫ total
includes taxes & fees
16 Jan - 17 Jan
Hyatt Regency St. Louis at The Arch

Moonrise Hotel

Moonrise Hotel
4.0 star property
7.7 km from Southhampton
9.0 out of 10, Wonderful, (1,920 reviews)
"Great staff | Fun decor | Fun area"
United States
Brett
The price is 3.268.126 ₫
3.886.761 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Moonrise Hotel

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 9.7 km from Southhampton
9.0 out of 10, Wonderful, (1,071 reviews)
"The staff was great, the amenities were fantastic, and it was close to everything we needed! 10/10 stay!"
United States
Dena
The price is 2.469.023 ₫
2.886.963 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Pear Tree Inn St. Louis Convention Center

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
6.2 km from Southhampton
9.4 out of 10, Exceptional, (849 reviews)
"Clean, would stay again."
United States
Eryka
The price is 2.880.396 ₫
3.522.665 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Courtyard by Marriott St. Louis Brentwood

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 9.8 km from Southhampton
8.8 out of 10, Excellent, (1,214 reviews)
"Staff was great and the hotel was in a good location."
United States
Candi
The price is 2.563.329 ₫
2.997.275 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
8.8 out of 10, Excellent, (1,025 reviews)
"This hotel was very clean And staff was friendly. "
United States
Laura
The price is 2.816.037 ₫
3.320.924 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Hilton Pennywell St. Louis at the Arch

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
25.1 km from Southhampton
9.6 out of 10, Exceptional, (1,049 reviews)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is 3.414.707 ₫
3.960.577 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Drury Plaza Hotel St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 star property
Downtown West, 7.9 km from Southhampton
9.2 out of 10, Wonderful, (1,001 reviews)
"Room was great! Staff were nice"
United States
Delaney
The price is 2.817.430 ₫
3.361.990 ₫ total
includes taxes & fees
12 Feb - 13 Feb
Fairfield Inn & Suites by Marriott St. Louis Downtown

La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
11.1 km from Southhampton
8.0 out of 10, Very good, (1,003 reviews)
"Very clean, excellant staff."
United States
John
The price is 2.524.386 ₫
2.934.295 ₫ total
includes taxes & fees
19 Jan - 20 Jan
La Quinta Inn & Suites by Wyndham St Louis Route 66

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
26.9 km from Southhampton
8.6 out of 10, Excellent, (777 reviews)
"Room was wonderful great location"
United States
Sandra
The price is 2.778.735 ₫
3.221.305 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Tru by Hilton St. Charles St. Louis, MO

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
26.6 km from Southhampton
8.4 out of 10, Very good, (1,001 reviews)
"Was an amazing hotel to stay at!! Clean spacious and very nice!!! Will stay here again!!"
United States
Darci
The price is 4.704.778 ₫
5.934.693 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Ameristar Casino Resort and Spa

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
27 km from Southhampton
9.4 out of 10, Exceptional, (1,000 reviews)
"We had a great stay in a beautiful area. The staff were friendly, and Kay at the front desk was so kind and welcoming!"
United States
Audrey
The price is 2.931.620 ₫
3.369.223 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Country Inn & Suites by Radisson, St. Charles Historic District

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
2.5 star property
12.9 km from Southhampton
9.6 out of 10, Exceptional, (1,000 reviews)
"Room was clean and staff was friendly."
United States
Anita
The price is 2.758.245 ₫
3.171.652 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights
3.0 star property
26 km from Southhampton
9.2 out of 10, Wonderful, (1,005 reviews)
"Excellent hotel with great staff, food and clean areas. "
United States
RANJITH
The price is 2.469.023 ₫
2.789.505 ₫ total
includes taxes & fees
19 Jan - 20 Jan
Drury Inn & Suites St. Louis Fairview Heights

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 9.5 km from Southhampton
8.8 out of 10, Excellent, (1,273 reviews)
"Great stay and staff "
United States
Mykeshia
The price is 2.886.438 ₫
3.432.811 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Embassy Suites by Hilton St. Louis Downtown

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis, 9.2 km from Southhampton
7.6 out of 10, Good, (1,079 reviews)
"Thanks!"
United States
Bilal
The price is 3.551.569 ₫
4.223.846 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Hilton St. Louis at the Ballpark

Casino Queen Hotel

Casino Queen Hotel
3.0 star property
10.4 km from Southhampton
7.6 out of 10, Good, (1,989 reviews)
"Yes it was a great stay"
United States
Suzy
The price is 2.210.536 ₫
2.563.780 ₫ total
includes taxes & fees
15 Jan - 16 Jan
Casino Queen Hotel

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
Dogtown, 4.7 km from Southhampton
9.4 out of 10, Exceptional, (1,000 reviews)
"Was perfect for a family stay. Nice rooms, quiet, close to Zoo and Science center."
United States
Joseph
The price is 2.886.438 ₫
3.403.947 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Hampton Inn & Suites St. Louis at Forest Park

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 8.9 km from Southhampton
9.4 out of 10, Exceptional, (1,108 reviews)
"Clean room, great restaurant and bar down stairs "
United States
Ambria
The price is 3.914.081 ₫
4.655.392 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Live by Loews - St.Louis

The Cheshire

The Cheshire
4.0 star property
5.5 km from Southhampton
8.6 out of 10, Excellent, (1,000 reviews)
"The place is beautiful, the room is very cozy and comfortable, the hotel well located with good breakfast. "
United States
Maria
The price is 3.383.185 ₫
4.017.126 ₫ total
includes taxes & fees
25 Jan - 26 Jan
The Cheshire
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Southhampton

Find the best Southhampton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

Top Southhampton Hotel Reviews

Frequently asked questions

What is Southhampton like?
Travellers to the Southhampton neighbourhood in St. Louis will be sure to enjoy their stay.
How many hotels should I expect to find in the Southhampton area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 22 Southhampton hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Southhampton, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer in Southhampton.
What can I see and do in this St. Louis neighbourhood?
A few places to visit in the area around Southhampton include Miniature Museum of Greater St. Louis, Lindenwood Park and River des Peres Greenway Trailhead. When you're sightseeing in St. Louis, Tower Grove Tennis Center and George Washington Carver Garden are also worth a stop.