Search Hotels Near St. Mary's Regional Medical Center, Lewiston

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23 Dec - 24 Dec
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26 Dec - 28 Dec
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Our top choices for St. Mary's Regional Medical Center hotels

Free daily buffet breakfast
Hampton Inn Lewiston-Auburn

Hampton Inn Lewiston-Auburn

Hampton Inn Lewiston-Auburn
2.5 star property
1.8 km from St. Mary's Regional Medical Center
9.4 out of 10, Exceptional, (924)
"Hotel was nice and clean. Staff was great. Mattress was not."
United States
Reginald
The price is 2.699.133 ₫
2.942.055 ₫ total
includes taxes & fees
23 Jan - 24 Jan 2026
Hampton Inn Lewiston-Auburn
Terrace/patio
Inn at the Agora

Inn at the Agora

Inn at the Agora
3.5 star property
1.3 km from St. Mary's Regional Medical Center
9.2 out of 10, Wonderful, (108)
"Charming, great place to stay. "
Canada
Keith
The price is 2.509.008 ₫
2.734.945 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Inn at the Agora
Exterior
The Munroe Inn

The Munroe Inn

The Munroe Inn
3.5 star property
2.4 km from St. Mary's Regional Medical Center
9.2 out of 10, Wonderful, (69)
"The host is very helpful."
United States
philip
The price is 4.239.613 ₫
4.621.178 ₫ total
includes taxes & fees
25 Dec - 26 Dec
The Munroe Inn
Lobby
Hilton Garden Inn Auburn Riverwatch

Hilton Garden Inn Auburn Riverwatch

Hilton Garden Inn Auburn Riverwatch
3.0 star property
2.1 km from St. Mary's Regional Medical Center
8.8 out of 10, Excellent, (1001)
"Great staff, clean rooms, good food"
United States
christopher
The price is 3.260.552 ₫
3.554.002 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hilton Garden Inn Auburn Riverwatch
Indoor pool
Ramada Hotel & Conference Center by Wyndham Lewiston

Ramada Hotel & Conference Center by Wyndham Lewiston

Ramada Hotel & Conference Center by Wyndham Lewiston
2.5 star property
3.1 km from St. Mary's Regional Medical Center
5.4 out of 10, (846)
"Room was clean"
United States
Swapnil
The price is 2.666.216 ₫
2.906.176 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Ramada Hotel & Conference Center by Wyndham Lewiston
Free daily continental breakfast
SureStay Hotel by Best Western Lewiston

SureStay Hotel by Best Western Lewiston

SureStay Hotel by Best Western Lewiston
2.5 star property
3.3 km from St. Mary's Regional Medical Center
8.2 out of 10, Very good, (449)
"Very clean. Nice stay!"
United States
Debbie
The price is 2.435.539 ₫
2.654.737 ₫ total
includes taxes & fees
25 Dec - 26 Dec
SureStay Hotel by Best Western Lewiston
Restaurant
Hampton Inn Oxford

Hampton Inn Oxford

Hampton Inn Oxford
2.5 star property
19.5 km from St. Mary's Regional Medical Center
9.0 out of 10, Wonderful, (1001)
"Just loved everything about the stay"
United States
Kevin
The price is 2.418.423 ₫
2.636.081 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hampton Inn Oxford
Restaurant
Oxford Casino Hotel

Oxford Casino Hotel

Oxford Casino Hotel
3.0 star property
19.7 km from St. Mary's Regional Medical Center
8.6 out of 10, Excellent, (1001)
"Room was clean and staff was friendly "
United States
Jimmy
The price is 3.294.258 ₫
3.590.741 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Oxford Casino Hotel
Aerial view
The Poland Spring Resort

The Poland Spring Resort

The Poland Spring Resort
3.5 star property
15.8 km from St. Mary's Regional Medical Center
8.0 out of 10, Very good, (822)
"Beautiful and very friendly staff!!"
United States
Angela
The price is 2.867.664 ₫
3.125.727 ₫ total
includes taxes & fees
25 Dec - 26 Dec
The Poland Spring Resort
Lobby
Quality Inn & Suites

Quality Inn & Suites

Quality Inn & Suites
2.5 star property
9.1 km from St. Mary's Regional Medical Center
7.6 out of 10, Good, (552)
"Room was great and staff was exceptional"
United States
Gordon
The price is 2.180.372 ₫
2.560.410 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Quality Inn & Suites
Lobby
Econo Lodge

Econo Lodge

Econo Lodge
2.0 star property
8.7 km from St. Mary's Regional Medical Center
7.4 out of 10, Good, (467)
"Wonderful place to stay will definitely stay again "
United States
Sara
The price is 1.835.410 ₫
2.184.401 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Econo Lodge
Standard Room, 1 King Bed | Desk, iron/ironing board, cots/infant beds, rollaway beds
Super 8 by Wyndham Lewiston Auburn Area

Super 8 by Wyndham Lewiston Auburn Area

Super 8 by Wyndham Lewiston Auburn Area
2.0 star property
5.5 km from St. Mary's Regional Medical Center
5.6 out of 10, (502)
"The room was clean and cofortable would stay there again"
United States
Candace
The price is 2.238.305 ₫
2.439.753 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Super 8 by Wyndham Lewiston Auburn Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Mary's Regional Medical Center Hotel Reviews

The Harraseeket Inn & Event House Freeport Downtown

The Harraseeket Inn & Event House Freeport Downtown

10/10 Excellent
"Yes, but no protein options for a lactose-intolerant person besides peanut butter."
Tracy 2-night trip
Posted 1 day ago
The Harraseeket Inn & Event House Freeport Downtown

Hotels near other St. Mary's Regional Medical Center attractions

The Public Theater

You can make plans for a show at The Public Theater on your trip to Lewiston. Wander the riverfront or discover the area's waterfalls.
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Androscoggin Bank Colisee

Catch an event at Androscoggin Bank Colisee during your trip to Lewiston. Stroll along the riverfront or discover the area's waterfalls.
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Frequently asked questions

What's the area like around St. Mary's Regional Medical Center?
St. Mary's Regional Medical Center is located in Lewiston. Travellers like the surrounding area for its waterfalls and riverfront. If you're looking for a convenient place to stay, take a look at the 5 hotels and other accommodation options you'll find within a mile.
How many hotels should I expect to find close to St. Mary's Regional Medical Center?
Expedia has 5 hotels and other accommodation options within a mile from St. Mary's Regional Medical Center.
If I need to cancel the hotel reservation for my stay near St. Mary's Regional Medical Center, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals close to St. Mary's Regional Medical Center.
What can I see and do near St. Mary's Regional Medical Center?
You can enjoy live performances at The Public Theater and Community Little Theatre. Spend some time wandering around Lake Grove Park, Bonney Park and Mount Apatite Park. Create some family memories at Androscoggin Bank Colisee and Roy's Driving Range.