Photo by Victoria S
Find hotels in Upstate South Carolina, SC from 1.538.548 ₫
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Go beyond your typical stay in Upstate South Carolina
Family friendly
Check prices for these dates
Top 10 Upstate South Carolina hotels and places to stay

DoubleTree by Hilton Greenville Woodruff Road
DoubleTree by Hilton Greenville Woodruff Road
9.2 out of 10, Wonderful, (1006)
The price is 2.718.804 ₫
2.990.684 ₫ total
includes taxes & fees
7 Sept - 8 Sept

Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph Collection
9.6 out of 10, Exceptional, (378)
The price is 6.849.700 ₫
7.534.670 ₫ total
includes taxes & fees
28 Sept - 29 Sept

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & Suites
9.0 out of 10, Wonderful, (1358)
The price is 2.228.787 ₫
2.451.665 ₫ total
includes taxes & fees
14 Sept - 15 Sept

Wingate by Wyndham - Greenville-Airport
Wingate by Wyndham - Greenville-Airport
8.4 out of 10, Very good, (1003)
The price is 2.397.395 ₫
2.637.135 ₫ total
includes taxes & fees
1 Sept - 2 Sept

Comfort Suites Greenville Airport
Comfort Suites Greenville Airport
9.4 out of 10, Exceptional, (1007)
The price is 2.584.445 ₫
2.842.889 ₫ total
includes taxes & fees
28 Sept - 29 Sept

Hampton Inn & Suites Greenville Airport, SC
Hampton Inn & Suites Greenville Airport, SC
9.2 out of 10, Wonderful, (937)
The price is 2.598.702 ₫
2.858.572 ₫ total
includes taxes & fees
12 Sept - 13 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Upstate South Carolina, SC
Showing deals for:12 Sep - 14 Sep
Image gallery for Hotel Hartness

Hotel Hartness
Greenville
9.8/10Exceptional (580 reviews)
10% off
Price is 7.643.870 ₫
18.631.711 ₫ total
includes taxes & fees
Save an average of 15% on thousands of hotels when you're signed in
Check out hotels with a hot tub in Upstate South Carolina

Lakeside Lodge Clemson
Lakeside Lodge Clemson
9.0 out of 10, Wonderful, (1002)
The price is 2.871.605 ₫
3.600.308 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Hotels with free breakfast in Upstate South Carolina you'll enjoy

Inn @ Clemson
Inn @ Clemson
8.2 out of 10, Very good, (1013)
The price is 2.345.684 ₫
2.603.708 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Hotels with a pool in Upstate South Carolina may fit your trip

Clemson University's James F. Martin Inn
Clemson University's James F. Martin Inn
9.6 out of 10, Exceptional, (928)
The price is 3.925.405 ₫
4.357.200 ₫ total
includes taxes & fees
31 Aug - 1 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Accommodation near Upstate South Carolina attractions
Clemson University

Clemson University
Enjoy the student vibe around Clemson University, a top university in Clemson. Experience the area's theatre scene or attend a football match.
Bob Jones University

Bob Jones University
Enjoy the student vibe when you visit Bob Jones University during your travels in Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Learn more about Upstate South Carolina
Check out the local area in Upstate South Carolina—home to attractions like Discovery Island Water Park and Heritage Park.

Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism
Top Upstate South Carolina Hotel Reviews
More cheap stays in Upstate South Carolina
More cheap stays in Upstate South Carolina

Best Western Plus Clemson Hotel & Conference Center
1310 Tiger Blvd, Clemson, SC
The price is 2.776.763 ₫ per night from 2 Sept to 3 Sept
2.776.763 ₫
3.082.207 ₫ total
2 Sept - 3 Sept
includes taxes & fees
8.2/10 Very Good! (1,008 reviews)
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Areas of Upstate South Carolina
- Hotels in Greenville Downtown
- Hotels in Nicholtown
- Hotels in West End
- Hotels in Green Avenue
- Hotels in Overbrook Historic District
- Hotels in Turtlehead
- Hotels in Payne-Logan
- Hotels in Pettigru Street Historic District
- Hotels in Pine Ridge Point
- Hotels in Woodside Cotton Mill Village Historic District
- Hotels in Hampton-Pinckney Historic District
- Hotels in Colonel Elias Earle Historic District
- Hotels in Chickasaw Point
- Hotels in Downtown
- Hotels in Indian Oaks
- Hotels in Serenity Bay
- Hotels in Cliff Ridge Colony
- Hotels in Keowee Plantation
- Hotels in Central Pacolet
- Hotels in Uptown Greenwood
Accommodation near Upstate South Carolina attractions
- Hotels near Clemson University
- Hotels near BMW Performance Center
- Hotels near Bon Secours Wellness Arena
- Hotels near Greenville Convention Center
- Hotels near Lake Jocassee
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near Bob Jones University
- Hotels near Devils Fork State Park
- Hotels near Table Rock State Park
- Hotels near Fluor Field at the West End
- Hotels near WestGate Mall
- Hotels near Anderson University
- Hotels near Spartanburg Memorial Auditorium
- Hotels near University of South Carolina Upstate
Search Upstate South Carolina Hotel Brands
Hotels Near Upstate South Carolina, South Carolina
- Greenville Hotels
- Highlands Hotels
- Clemson Hotels
- Hendersonville Hotels
- North Georgia Mountains Hotels
- Franklin Hotels
- Brevard Hotels
- Hiawassee Hotels
- Rock Hill Hotels
- Anderson Hotels
- Black Mountain Hotels
- Spartanburg Hotels
- Cashiers Hotels
- Lake Lure Hotels
- Tiger Hotels
- Seneca Hotels
- Sylva Hotels
- Clayton Hotels
- Gastonia Hotels
- Sautee Nacoochee Hotels
More ways to book
Expedia's Latest Trends
General