Search Hotels in Uptown, Beaufort

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
13 Dec - 14 Dec
Tomorrow
14 Dec - 15 Dec
Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Uptown hotels

Meeting facility
The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa
4.0 star property
25.6 km from Uptown
8.4 out of 10, Very good, (1002)
"Beautiful room. Ocean view. The hotel was magical "
United States
Shirene
The price is 3.331.782 ₫
4.863.243 ₫ total
includes taxes & fees
28 Dec - 29 Dec
The Westin Hilton Head Island Resort & Spa
Exterior
Holiday Inn Express Bluffton at Hilton Head Area by IHG

Holiday Inn Express Bluffton at Hilton Head Area by IHG

Holiday Inn Express Bluffton at Hilton Head Area by IHG
2.5 star property
26.4 km from Uptown
9.0 out of 10, Wonderful, (1003)
"Was a great place to stay, its behind an alley for target, but was safe with no issues. "
United States
Michael
The price is 2.709.621 ₫
2.980.583 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Bluffton at Hilton Head Area by IHG
Property grounds
Beaufort Inn

Beaufort Inn

Beaufort Inn
3.5 star property
Downtown Beaufort, 0.9 km from Uptown
9.0 out of 10, Wonderful, (1001)
"If you are looking for a unique place to stay, this would be it. Staff was great and the rooms were clean."
United States
Samantha
The price is 3.527.769 ₫
4.285.674 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Beaufort Inn
Exterior
Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC
2.5 star property
4.6 km from Uptown
9.0 out of 10, Wonderful, (707)
"Awesome stay!!!"
United States
Michael
The price is 2.504.426 ₫
2.754.869 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Tru by Hilton Beaufort, SC
Business centre
Best Western Sea Island Inn

Best Western Sea Island Inn

Best Western Sea Island Inn
2.5 star property
The Bluff, 0.9 km from Uptown
9.4 out of 10, Exceptional, (1000)
"Perfect spot!"
United States
Tricia
The price is 3.672.632 ₫
4.039.896 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Sea Island Inn
Lobby
Hilton Garden Inn Hilton Head

Hilton Garden Inn Hilton Head

Hilton Garden Inn Hilton Head
3.0 star property
25.8 km from Uptown
8.6 out of 10, Excellent, (1001)
"Wonderful stay!"
United States
Ashley
The price is 2.310.544 ₫
2.541.598 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn Hilton Head
Lobby
Hampton Inn Hilton Head

Hampton Inn Hilton Head

Hampton Inn Hilton Head
2.5 star property
25 km from Uptown
8.4 out of 10, Very good, (1003)
"Nice staff, clean room, tasty food "
United States
William
The price is 2.399.198 ₫
2.639.118 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Hilton Head
Exterior
SpringHill Suites by Marriott Beaufort

SpringHill Suites by Marriott Beaufort

SpringHill Suites by Marriott Beaufort
2.5 star property
2.1 km from Uptown
9.4 out of 10, Exceptional, (1020)
"Would stay here again"
United States
Jennifer
The price is 2.709.621 ₫
2.980.584 ₫ total
includes taxes & fees
19 Dec - 20 Dec
SpringHill Suites by Marriott Beaufort
Indoor pool, 3 outdoor pools, pool cabanas (surcharge), pool umbrellas
Marriott's Barony Beach Club

Marriott's Barony Beach Club

Marriott's Barony Beach Club
3.5 star property
25.6 km from Uptown
9.6 out of 10, Exceptional, (241)
"The staff was so kind. The property and room was clean. "
United States
Sarah
The price is 5.129.865 ₫
5.642.852 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Marriott's Barony Beach Club
Restaurant
Hampton Inn Yemassee/Point South

Hampton Inn Yemassee/Point South

Hampton Inn Yemassee/Point South
2.5 star property
28.8 km from Uptown
8.8 out of 10, Excellent, (770)
"Great front desk service and good food"
United States
Stephen
The price is 3.429.907 ₫
3.875.797 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn Yemassee/Point South
Terrace/patio
Home2 Suites by Hilton Hilton Head

Home2 Suites by Hilton Hilton Head

Home2 Suites by Hilton Hilton Head
3.0 star property
29.9 km from Uptown
9.0 out of 10, Wonderful, (673)
"Rooms are very nice and spacious."
United States
Lori
The price is 2.504.426 ₫
2.754.869 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Home2 Suites by Hilton Hilton Head
Basic Room, Multiple Beds, Non Smoking | Free WiFi, bed sheets
Simple Rewards Inn

Simple Rewards Inn

Simple Rewards Inn
2.5 star property
25.6 km from Uptown
8.8 out of 10, Excellent, (1001)
"Great coffee and breakfast"
United States
Richard
The price is 2.393.937 ₫
2.633.331 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Simple Rewards Inn
Bar (on property)
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
3.0 star property
2 km from Uptown
8.2 out of 10, Very good, (1005)
"Nice room"
United States
Katherine
The price is 2.341.323 ₫
2.575.455 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
Gym
City Loft Hotel

City Loft Hotel

City Loft Hotel
3.5 star property
Historic District, 1 km from Uptown
9.4 out of 10, Exceptional, (758)
"Great place to stay in city center Beaufort. Easy free parking, friendly staff, comfy mattresses, nice bathroom and shower. Location was perfect for walking to shops and restaurants."
United States
Laura
The price is 3.755.061 ₫
4.130.462 ₫ total
includes taxes & fees
14 Dec - 15 Dec
City Loft Hotel
Lobby
Best Western Point South

Best Western Point South

Best Western Point South
2.5 star property
28.4 km from Uptown
8.0 out of 10, Very good, (1004)
"Room was clean Staff was friendly "
United States
Brian
The price is 2.341.323 ₫
2.645.695 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Best Western Point South
Exterior
Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort
3.0 star property
1.4 km from Uptown
8.4 out of 10, Very good, (1001)
"Good hotel"
United States
joshua
The price is 2.083.514 ₫
2.291.866 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Garden Inn Beaufort
Reception
Hampton Inn Beaufort

Hampton Inn Beaufort

Hampton Inn Beaufort
2.5 star property
2.5 km from Uptown
8.4 out of 10, Very good, (1001)
"Room was spotless and staff very courtesy."
United States
Griselda
The price is 2.293.970 ₫
2.523.368 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Beaufort
Property amenity
SpringHill Suites by Marriott Hilton Head Island

SpringHill Suites by Marriott Hilton Head Island

SpringHill Suites by Marriott Hilton Head Island
2.5 star property
29.8 km from Uptown
8.6 out of 10, Excellent, (576)
"Very clean, accommodating and close to a lot of attractions will stay here again. "
United States
Al
The price is 2.578.086 ₫
2.835.894 ₫ total
includes taxes & fees
21 Dec - 22 Dec
SpringHill Suites by Marriott Hilton Head Island
Free daily continental breakfast
Spark by Hilton Bluffton Hilton Head Island

Spark by Hilton Bluffton Hilton Head Island

Spark by Hilton Bluffton Hilton Head Island
2.5 star property
25.7 km from Uptown
8.4 out of 10, Very good, (149)
"Nice hotel "
United States
Robert
The price is 2.083.514 ₫
2.291.865 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Spark by Hilton Bluffton Hilton Head Island
Egyptian cotton sheets, premium bedding, pillow-top beds
The Emerald Boutique Stays

The Emerald Boutique Stays

The Emerald Boutique Stays
2.5 star property
The Old Point, 0.8 km from Uptown
9.2 out of 10, Wonderful, (220)
"Close to downtown shopping and restaurants. Nice room and helpful staff."
United States
Jeffrey
The price is 3.393.603 ₫
3.732.963 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Emerald Boutique Stays
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

Historic District

While visiting Historic District, you might make a stop by sights like Bay Street and Henry C. Chambers Waterfront Park.

Downtown Beaufort

While visiting Downtown Beaufort, you might make a stop by sights like Henry C. Chambers Waterfront Park and Bay Street.

Habersham

If you're looking for some top things to see and do in Habersham and surrounding area, you can visit Highway 21 Drive-In Theater and Ocean Creek.

The Old Commons

If you're looking for some top things to see and do in The Old Commons and surrounding area, you can visit Bay Street and Henry C. Chambers Waterfront Park.

Northwest Quadrant

While there might not be top attractions in Northwest Quadrant, you can explore the larger area and discover places like Beaufort National Cemetery and Henry C. Chambers Waterfront Park.

Top Uptown Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Uptown?
Travellers will be sure to enjoy their time in Beaufort's Uptown neighbourhood.
How many hotels will I be able to find in Uptown?
If you're searching for places to stay in Beaufort, choose from one of Expedia's 12 hotels and other accommodation options in Uptown.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Uptown.
What is there to do in this Beaufort neighbourhood?
A few places to visit in the area around Uptown include Beaufort National Cemetery, USCB Center for the Arts and St. Helena's Episcopal Church. Beaufort Museum and Henry C. Chambers Waterfront Park are also worth a visit when you're out sightseeing in Beaufort.