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Search Hotels in Uptown, San Antonio

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Our top choices for Uptown hotels

WoodSpring Suites San Antonio Stone Oak

WoodSpring Suites San Antonio Stone Oak
2.5 star property
Uptown
8.2 out of 10, Very good, (687)
"Staff was nice and friendly! The location had very easy access to the freeway. "
United States
Lidiana
The price is 1.920.148 ₫
2.269.788 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
WoodSpring Suites San Antonio Stone Oak

Home2 Suites by Hilton San Antonio North-Stone Oak, TX

Home2 Suites by Hilton San Antonio North-Stone Oak, TX
3.0 star property
Uptown
8.8 out of 10, Excellent, (874)
"Clean and nice rooms, very nice breakfast although not perfect"
United States
Youcai
The price is 2.146.651 ₫
2.537.535 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Home2 Suites by Hilton San Antonio North-Stone Oak, TX

Spark by Hilton San Antonio Airport

Spark by Hilton San Antonio Airport
2.0 star property
Uptown
8.6 out of 10, Excellent, (1029)
"Great time staying at this location."
United States
Amy
The price is 1.683.648 ₫
1.999.061 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Spark by Hilton San Antonio Airport

Estancia del Norte San Antonio, Tapestry Collection by Hilton

Estancia del Norte San Antonio, Tapestry Collection by Hilton
3.5 star property
Uptown
8.8 out of 10, Excellent, (1003)
"The staff was friendly, the room was spacious yet cosy and the bed was so comfortable "
United States
Lauren
The price is 3.555.391 ₫
4.202.792 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Estancia del Norte San Antonio, Tapestry Collection by Hilton

Days Inn by Wyndham San Antonio Airport

Days Inn by Wyndham San Antonio Airport
2.0 star property
Uptown
8.0 out of 10, Very good, (1004)
"Great place to lie your head right close to the airport "
Canada
Kevin
The price is 1.374.541 ₫
1.604.727 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Days Inn by Wyndham San Antonio Airport

Comfort Suites San Antonio North - Stone Oak

Comfort Suites San Antonio North - Stone Oak
2.5 star property
Uptown
8.6 out of 10, Excellent, (1006)
"Excellent stay, great place highly recommended "
United States
Cesar
The price is 1.990.125 ₫
2.323.470 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Comfort Suites San Antonio North - Stone Oak

Americas Best Value Inn San Antonio Airport South

Americas Best Value Inn San Antonio Airport South
2.0 star property
Uptown
7.8 out of 10, Good, (312)
"Clean rooms, great location, very helpful staff and restaurants near by walking distance. "
United States
Mark
The price is 1.446.885 ₫
1.689.172 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Americas Best Value Inn San Antonio Airport South

Embassy Suites by Hilton San Antonio Airport

Embassy Suites by Hilton San Antonio Airport
3.5 star property
Uptown
8.8 out of 10, Excellent, (1066)
"Great stay!"
United States
darryl
The price is 3.135.794 ₫
3.706.790 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Embassy Suites by Hilton San Antonio Airport

Super 8 by Wyndham San Antonio/I-35 North

Super 8 by Wyndham San Antonio/I-35 North
2.0 star property
Uptown
6.8 out of 10, (1001)
"Clean room"
United States
Esmeralda
The price is 1.183.815 ₫
1.382.103 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Super 8 by Wyndham San Antonio/I-35 North

Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown
9.4 out of 10, Exceptional, (1021)
"Great area."
United States
Ricardo
The price is 2.482.065 ₫
2.934.019 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Wyndham Garden San Antonio Airport

Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
Uptown
9.4 out of 10, Exceptional, (1939)
"Always happy to stay at the Drury Inn. Rooms are clean and staff are friendly. "
United States
Rocio
The price is 2.367.367 ₫
2.798.276 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Plaza Hotel San Antonio Airport

Courtyard by Marriott San Antonio Airport

Courtyard by Marriott San Antonio Airport
3.0 star property
Uptown
8.4 out of 10, Very good, (1001)
"Very friendly and courteous staff, great breakfast."
United States
Viju
The price is 2.341.323 ₫
2.767.655 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott San Antonio Airport

Courtyard by Marriott San Antonio Airport/North Star Mall

Courtyard by Marriott San Antonio Airport/North Star Mall
3.0 star property
Uptown
8.2 out of 10, Very good, (788)
"good place to stay"
United States
nadine
The price is 2.083.514 ₫
2.432.503 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott San Antonio Airport/North Star Mall

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown
8.2 out of 10, Very good, (1008)
"Clean room, friendly and helpful staff."
United States
Robyn
The price is 1.565.003 ₫
1.827.141 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Best Western Garden Inn

SureStay Plus Hotel by Best Western San Antonio North

SureStay Plus Hotel by Best Western San Antonio North
2.5 star property
Uptown
7.0 out of 10, Good, (1002)
"The staff members were very helpful and friendly, my room was clean and check-in was a smooth process "
United States
Reginald
The price is 1.363.755 ₫
1.592.184 ₫ total
includes taxes & fees
21 Dec - 22 Dec
SureStay Plus Hotel by Best Western San Antonio North

SpringHill Suites by Marriott San Antonio Airport

SpringHill Suites by Marriott San Antonio Airport
3.0 star property
Uptown
7.8 out of 10, Good, (1001)
"Close to airport and free shuttle. Great place "
United States
Lorena
The price is 2.472.858 ₫
2.923.141 ₫ total
includes taxes & fees
23 Dec - 24 Dec
SpringHill Suites by Marriott San Antonio Airport

Hilton Garden Inn San Antonio Airport

Hilton Garden Inn San Antonio Airport
3.0 star property
Uptown
8.0 out of 10, Very good, (1003)
"Staff is outstanding!"
United States
David
The price is 2.293.970 ₫
2.711.678 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn San Antonio Airport

Motel 6 San Antonio, TX – I-35 North Corridor

Motel 6 San Antonio, TX – I-35 North Corridor
2.0 star property
Uptown
6.8 out of 10, (114)
"Room was clean"
United States
blanca
The price is 1.041.494 ₫
1.215.909 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Motel 6 San Antonio, TX – I-35 North Corridor

Hilton Garden Inn San Antonio Airport South

Hilton Garden Inn San Antonio Airport South
3.0 star property
Uptown
8.4 out of 10, Very good, (1001)
"Friendly Staff and Clean Room"
United States
Patrick
The price is 2.005.383 ₫
2.415.664 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn San Antonio Airport South

Comfort Suites San Antonio Airport North

Comfort Suites San Antonio Airport North
2.5 star property
Uptown
7.8 out of 10, Good, (643)
"Great place"
United States
Guadalupe
The price is 1.841.490 ₫
2.215.708 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites San Antonio Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

Downtown San Antonio

A scenic riverfront great entertainment and top sights from Aztec Theater to San Antonio River – discover Downtown San Antonio, a destination also famous for its historic sites.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Convocation Center are top sights worth seeing.

Top Uptown Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Uptown?
Guests are sure to enjoy their time checking out all that San Antonio's Uptown neighbourhood has to offer. Are you looking for Uptown travel tips? Make sure that you visit Marion Koogler McNay Art Museum and Alamo Quarry Market while you're in the neighbourhood.
How many hotels will I be able to find in the Uptown area?
Expedia has 373 hotels and other accommodation options in Uptown to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Uptown, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown.
What can I see and do in this San Antonio neighbourhood?
Uptown's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to Alamo Quarry Market or San Antonio Zoo and Aquarium while you're in the neighbourhood. A few places to visit in the area around Uptown include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. McDermott Center and UIW Tennis Center are also worth a visit when you're out sightseeing in San Antonio.