What's it like in Uptown?

Guests are sure to enjoy their time checking out all that San Antonio's Uptown neighbourhood has to offer. Experience the best of Uptown with a visit to San Antonio Zoo and Aquarium and San Antonio River during your trip.

How many hotels will I be able to find in the Uptown area?

Expedia has 364 hotels and other accommodation options in Uptown to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown.

What can I see and do in this San Antonio neighbourhood?

Uptown's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to San Antonio Zoo and Aquarium or San Antonio River while you're in the neighbourhood. A few places to visit in the area around Uptown include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. Alamo Quarry Market and McDermott Center are also worth a visit when you're out sightseeing in San Antonio.

The Best Hotels in Uptown, San Antonio - 2025 Updated Prices

Top Trending Hotels Near Uptown, San Antonio

"Great stay!"

3.521.675 ₫ total

includes taxes & fees

3 Jul - 4 Jul

"Great stay"

1.640.725 ₫ total

includes taxes & fees

6 Jul - 7 Jul

"Clean friendly hotel "

"Great stay"

2.395.724 ₫ total

includes taxes & fees

2 Aug - 3 Aug

"Wonderful place to stay"

2.474.083 ₫ total

includes taxes & fees

7 Jul - 8 Jul

"I loved the indoor pool and jet tubs in the room"

2.752.536 ₫ total

includes taxes & fees

11 Jul - 12 Jul

"Great location."

2.285.940 ₫ total

includes taxes & fees

8 Jul - 9 Jul

"This is an extended stay"

2.656.162 ₫ total

includes taxes & fees

3 Jul - 4 Jul

"Clean hotel, easy check in/out"

3.990.884 ₫ total

includes taxes & fees

1 Aug - 2 Aug

"Great place to stay!"

3.675.814 ₫ total

includes taxes & fees

11 Jul - 12 Jul

"Overall all good fast check in"

3.169.232 ₫ total

includes taxes & fees

25 Jul - 26 Jul

"Front desk staff was extremely helpful"

3.366.923 ₫ total

includes taxes & fees

3 Jul - 4 Jul

"Comfortable hotel close to the airport."

2.431.948 ₫ total

includes taxes & fees

20 Jul - 21 Jul

"Convenient location, close to lots of shopping & restaurants."

3.125.059 ₫ total

includes taxes & fees

28 Jul - 29 Jul

Breakfast and dinner served, American cuisine

"The front desk ladies are very helpful "

"Clean, great location. Good breakfast, happy hour & very comfortable bed!"

2.779.555 ₫ total

includes taxes & fees

6 Jul - 7 Jul

"We went for my sons baseball tournament, friendly staff. Breakfast was good and fulfilling for the family the staff in the breakfast area very helpful with special food instructions. Overall great staff and clean hotel "

"We enjoyed our stay here"

2.333.552 ₫ total

includes taxes & fees

16 Jul - 17 Jul

"Great hotel"

3.544.534 ₫ total

includes taxes & fees

9 Jul - 10 Jul

"Great staff, awesome breakfast buffet, rooms are clean and comfortable"

2.625.121 ₫ total

includes taxes & fees

6 Jul - 7 Jul

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

Downtown - Riverwalk showing a river or creek, a bridge and boating

Downtown San Antonio

A scenic riverfront great entertainment and top sights from San Antonio River to Alamo – discover Downtown San Antonio, a destination also famous for its historic sites.

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