Compare and book 4 Star hotels in St. Charles, St. Louis

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Check availability on St. Charles 4 Star Hotels

Tonight
2 Mar - 3 Mar
Tomorrow
3 Mar - 4 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

Our top choices for St. Charles 4-star hotels

Premium bedding, down duvets, pillow-top beds, in-room safe

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,002 reviews)
"Great stay will be back"
United States
Tashari
The price is 3.300.246 ₫
3.858.945 ₫ total
includes taxes & fees
8 Mar - 9 Mar
The Westin St. Louis
Restaurant

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,632 reviews)
"Everything was great i can’t wait to stay again "
United States
Kimbriel
The price is 3.300.506 ₫
3.989.539 ₫ total
includes taxes & fees
23 Mar - 24 Mar
21C Museum Hotel St Louis
Exterior

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (4,002 reviews)
"Nice room & friendly staff!"
United States
Cynthia
The price is 4.143.222 ₫
4.886.061 ₫ total
includes taxes & fees
28 Mar - 29 Mar
Hyatt Regency St. Louis at The Arch
Exterior

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,128 reviews)
"Very nice hotel! Amazing staff and lovely rooms!"
United States
Stephanie
The price is 4.143.222 ₫
4.927.494 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Live by Loews - St.Louis
5 restaurants, breakfast, lunch, dinner served; American cuisine

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,492 reviews)
"Clean and comfy great food "
United States
Theresa A
The price is 2.501.307 ₫
3.290.604 ₫ total
includes taxes & fees
4 Mar - 5 Mar
River City Casino & Hotel
Snack bar

DoubleTree by Hilton St. Louis Airport

DoubleTree by Hilton St. Louis Airport
4.0 star property
Woodson Terrace
7.8 out of 10, Good, (895 reviews)
"It was nice very friendly lady that checked us in"
United States
Tracey
The price is 2.685.798 ₫
3.151.461 ₫ total
includes taxes & fees
8 Mar - 9 Mar
DoubleTree by Hilton St. Louis Airport
Bar (on property)

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,246 reviews)
"Wonderful stay"
United States
David
The price is 2.768.662 ₫
3.292.742 ₫ total
includes taxes & fees
11 Mar - 12 Mar
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Meeting facility

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,075 reviews)
"Everything was excellent. "
United States
JOHN
The price is 3.309.366 ₫
3.871.560 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Renaissance St. Louis Airport Hotel
Seasonal outdoor pool

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1,005 reviews)
"The room was great. I enjoyed my stay. "
United States
Wanda
The price is 4.432.466 ₫
5.612.633 ₫ total
includes taxes & fees
9 Mar - 10 Mar
Ameristar Casino Resort and Spa
Property amenity

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,920 reviews)
"The staff was wonderful. Very unique hotel it was awesome."
United States
Jaden
The price is 3.611.639 ₫
4.295.662 ₫ total
includes taxes & fees
4 Mar - 5 Mar
Moonrise Hotel
Seasonal outdoor pool

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1,000 reviews)
"The staff was great and the room was huge! Loved our stay "
United States
Kathryn
The price is 3.882.642 ₫
5.346.950 ₫ total
includes taxes & fees
8 Mar - 9 Mar
The Royal Sonesta Chase Park Plaza St. Louis
Lobby

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,002 reviews)
"Beautiful historic hotel with great service."
United States
Rebecca
The price is 5.201.437 ₫
6.186.016 ₫ total
includes taxes & fees
22 Mar - 23 Mar
St. Louis Union Station Hotel, Curio Collection by Hilton
3 bars/lounges, rooftop bar

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,078 reviews)
"Great location. Nice place to stay. "
United States
Beth
The price is 4.340.742 ₫
5.162.400 ₫ total
includes taxes & fees
16 Mar - 17 Mar
Hilton St. Louis at the Ballpark
Terrace/patio

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,059 reviews)
"Clean room and great staff"
United States
Chenier
The price is 3.300.246 ₫
3.892.023 ₫ total
includes taxes & fees
5 Mar - 6 Mar
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
In-room safe, desk, blackout curtains, iron/ironing board

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very good, (1,005 reviews)
"Clean, quiet, and the staff were great"
United States
Cherry
The price is 3.611.118 ₫
4.258.554 ₫ total
includes taxes & fees
15 Mar - 16 Mar
DoubleTree by Hilton St. Louis Forest Park
Exterior

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very good, (1,002 reviews)
"Room was very nice. Beds super comfy. Hotel lobby provided a great space to gather with friends."
United States
Kimberly
The price is 3.960.816 ₫
4.710.558 ₫ total
includes taxes & fees
9 Mar - 10 Mar
Marriott St. Louis Grand
Exterior

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,289 reviews)
"Clean room, great breakfast, perfect location."
United States
Kevin
The price is 3.183.766 ₫
3.786.420 ₫ total
includes taxes & fees
8 Mar - 9 Mar
Embassy Suites by Hilton St. Louis Downtown
Lobby

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End
9.0 out of 10, Wonderful, (714 reviews)
"Room was clean nice staff"
United States
Brandon
The price is 3.413.598 ₫
4.025.623 ₫ total
includes taxes & fees
8 Mar - 9 Mar
AC Hotel St. Louis Central West End
Gastropub

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1,001 reviews)
"The place is beautiful, the room is very cozy and comfortable, the hotel well located with good breakfast. "
United States
Maria
The price is 3.989.219 ₫
4.736.718 ₫ total
includes taxes & fees
5 Mar - 6 Mar
The Cheshire
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, pool loungers

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (696 reviews)
"The gym was amazing! "
United States
Hannah
The price is 3.523.042 ₫
4.147.959 ₫ total
includes taxes & fees
15 Mar - 16 Mar
Le Méridien St. Louis Clayton
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Charles.
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
The price is 13.002.942 ₫ per night from 8 Mar to 9 Mar
13.002.942 ₫
15.179.374 ₫ total
8 Mar - 9 Mar
includes taxes & fees
9.2/10 Wonderful! (557 reviews)
Still don't see what you're looking for?
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PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

See all hotels in St. Charles
Urban Tree Canopy in historic Saint Charles Missouri

Top St. Charles Hotel Reviews

Marriott St. Louis Grand

Marriott St. Louis Grand

10/10 Excellent
"Friendly staff, comfy, big, lots of amenities. "
Norman 1-night trip
Posted 4 days ago
Marriott St. Louis Grand

Frequently asked questions

What are the best 4-star hotels in St. Charles?
Look forward to 4-star hotel comfort at Ameristar Casino Resort and Spa. Rated highly by many of our guests, it features spa facilities and a spa tub. Also check out DoubleTree by Hilton St. Louis - Westport. Concierge services and a pillowtop mattress make this retreat another in-demand pick in St. Charles.
How much does it cost to stay in a 4-star hotel in St. Charles?
To find a 4-star hotel in St. Charles that fits your budget, use Expedia's sort and search filters. Check out the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also list your results by the most wallet-friendly option first.

  • Search for the lowest price from 12.644.783 ₫

What's the difference between 5-star and 4-star hotels in St. Charles?
Treat yourself to luxury during your St. Charles getaway by choosing a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically filled with amenities like large beds, complimentary bathrobes and more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and special one. Round-the-clock concierge assistance, elegant furnishings and gourmet dining are just the start of the first-rate services and conveniences you'll likely have access to.