St. Charles Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in St. Charles
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
The price is 4.189.985 ₫ per night from 1 Jul to 2 Jul
4.189.985 ₫
5.333.488 ₫ total
1 Jul - 2 Jul
includes taxes & fees
8.6/10 Excellent! (1,003 reviews)
"The door on the toilet room is a really tight squeeze and actually stubbed my toe but other than that (oh and I thought there was a microwave but there was not) it was a good stay with a cool view of the river. Will take more advantage of the pool next time. We were there for a wedding this ..."
Reviewed on 1 Jun 2026
Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive St. Charles MO
Fully refundableReserve now, pay when you stay
The price is 3.815.122 ₫ per night from 14 Jun to 15 Jun
3.815.122 ₫
4.422.758 ₫ total
14 Jun - 15 Jun
includes taxes & fees
9.6/10 Exceptional! (1,007 reviews)
"Christina at the front desk is a Rock Star! She is extremely helpful, knowledgeable and goes about her business in a professional manner! You can’t go wrong staying at Drury Inns!"
Reviewed on 1 Jun 2026
Comfort Suites St Charles - St Louis
1400 S 5th St St. Charles MO
Fully refundable
The price is 2.725.332 ₫ per night from 7 Jun to 8 Jun
2.725.332 ₫
3.132.224 ₫ total
7 Jun - 8 Jun
includes taxes & fees
8.4/10 Very Good! (1,002 reviews)
"We had a great stay"
Reviewed on 1 Jun 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Gateway Arch
Find out about the history of Gateway Arch, one of the top monuments in St. Louis. Experience the area's fascinating museums or attend a baseball game.
St. Louis Zoo
Why not visit the animals who live at St. Louis Zoo and see why this is a favourite attraction in St. Louis? Amble around the area's lush forest or attend a sporting event.
