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19 Dec - 20 Dec
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Our top choices for Historic Main Street hotels

Lobby
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
1.8 km from Historic Main Street
9.6 out of 10, Exceptional, (1000)
"Staff and hotel were amazing"
United States
Allison
The price is 3.026.997 ₫
3.508.989 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Drury Plaza Hotel St. Louis St. Charles
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District, 1 km from Historic Main Street
9.4 out of 10, Exceptional, (1001)
"Good stay."
United States
Steven
The price is 2.917.752 ₫
3.353.285 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Free daily buffet breakfast
Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area

Hampton Inn & Suites St. Charles Old Town Area
2.5 star property
1.5 km from Historic Main Street
9.2 out of 10, Wonderful, (632)
"Clean room, great staff, liked the gym"
United States
Emily
The price is 2.568.696 ₫
3.109.433 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites St. Charles Old Town Area
Lobby
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
2.1 km from Historic Main Street
8.6 out of 10, Excellent, (1008)
"I Loved it I would definitely stay there again"
United States
Roberta
The price is 3.216.266 ₫
3.696.358 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites by Hilton St. Louis St. Charles
Exterior
Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO

Tru by Hilton St. Charles St. Louis, MO
2.5 star property
2.1 km from Historic Main Street
8.6 out of 10, Excellent, (769)
"Great staff and room was so nice and comfortable "
United States
ED
The price is 2.352.839 ₫
2.727.575 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Tru by Hilton St. Charles St. Louis, MO
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
1.5 km from Historic Main Street
8.4 out of 10, Very good, (1007)
"Nice staff at reception. "
United States
Denise
The price is 2.001.414 ₫
2.300.166 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites St Charles - St Louis
Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
1.4 km from Historic Main Street
8.4 out of 10, Very good, (1000)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is 4.005.197 ₫
5.117.386 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Ameristar Casino Resort and Spa
Front of property – evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
3 km from Historic Main Street
8.4 out of 10, Very good, (2222)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is 3.080.464 ₫
3.977.035 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hollywood Casino & Hotel St. Louis
Lobby sitting area
Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel

Best Western Plus The Charles Hotel
3.0 star property
1.4 km from Historic Main Street
8.0 out of 10, Very good, (1011)
"The room is decent for a night. The price is great and hotel staff is friendly. "
United States
Jordan
The price is 2.327.042 ₫
2.697.670 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Best Western Plus The Charles Hotel
Terrace/patio
Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG

Holiday Inn St. Louis Arpt West-Earth City by IHG
3.5 star property
2.9 km from Historic Main Street
7.6 out of 10, Good, (1007)
"It’s near to the exit to the highway "
United States
Gabriel
The price is 1.947.976 ₫
2.239.939 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Holiday Inn St. Louis Arpt West-Earth City by IHG
Property amenity
Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham

Elimwood Hotel, a Ramada by Wyndham
3.0 star property
3.1 km from Historic Main Street
7.4 out of 10, Good, (1000)
"Everything was nice"
United States
Ronald
The price is 2.369.160 ₫
2.747.940 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Elimwood Hotel, a Ramada by Wyndham
Interior entrance
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
1.6 km from Historic Main Street
5.8 out of 10, (1005)
"Nice staff, respectful."
United States
LaurenRenee
The price is 1.565.631 ₫
1.814.990 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Americas Best Value Inn & Suites St. Louis, St. Charles Inn
Lobby
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
10.6 km from Historic Main Street
9.4 out of 10, Exceptional, (2745)
"Great place to stay before your early morning flight. "
United States
Henry
The price is 2.368.897 ₫
2.788.765 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Pear Tree Inn St. Louis Airport
Lobby
Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
12 km from Historic Main Street
9.4 out of 10, Exceptional, (1005)
"Great hotel! Clean, friendly staff, wonderful amenities!"
United States
Susan
The price is 2.895.377 ₫
3.328.407 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Drury Inn & Suites St. Louis St. Peters
Lobby
Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
2.5 star property
9.5 km from Historic Main Street
9.2 out of 10, Wonderful, (810)
"Everything was great "
United States
Alan
The price is 3.110.181 ₫
3.607.438 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Fairfield Inn & Suites St Louis Westport
Free daily buffet breakfast
SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City
3.0 star property
4.2 km from Historic Main Street
8.8 out of 10, Excellent, (1000)
"Location wasn’t the greatest but the room was awesome. "
United States
Shawn
The price is 2.737.696 ₫
3.261.216 ₫ total
includes taxes & fees
28 Dec - 29 Dec
SpringHill Suites by Marriott St. Louis Airport/Earth City
Lobby
Residence Inn St Louis Westport

Residence Inn St Louis Westport

Residence Inn St Louis Westport
3.0 star property
9.5 km from Historic Main Street
9.2 out of 10, Wonderful, (411)
"Great room for the price. Breakfast was amazing and the staff is super friendly! "
United States
Jimmy
The price is 3.885.422 ₫
4.506.623 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn St Louis Westport
Exterior
WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
15.4 km from Historic Main Street
9.6 out of 10, Exceptional, (19)
"Very nice place. Clean room. Staff was excellent. "
United States
Richard
The price is 1.947.976 ₫
2.306.373 ₫ total
includes taxes & fees
22 Dec - 23 Dec
WoodSpring Suites St Peters-OFallon
Lobby
Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
15.8 km from Historic Main Street
9.6 out of 10, Exceptional, (1036)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is 3.421.857 ₫
3.968.870 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Drury Plaza Hotel St. Louis Chesterfield
Free daily continental breakfast
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
10.7 km from Historic Main Street
9.2 out of 10, Wonderful, (1503)
"The room was very clean and the staff was very helpful."
United States
John
The price is 2.841.676 ₫
3.345.781 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Wingate by Wyndham St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Historic Main Street Hotel Reviews

Hotels near other Historic Main Street attractions

Lewis & Clark festival
Photo by HA
Open Photo by HA

Frontier Park

You can find out about the history of St. Charles with a stop at Frontier Park. Visit the shops and top-notch restaurants in this walkable area.
See properties
trestle on Katy Trail in Missouri over Auxvasse Creek near Mokane - 237 mile bike trail stretching across most of the state of Missouri converted from abandoned railroad

Katy Trail

4.6/5 (53 reviews)
You can take time to visit Katy Trail during your travels to St. Charles. Experience the acclaimed theatre scene and great live music in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Historic Main Street?
Historic Main Street is located in St. Charles. This historic area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 91 hotels and other accommodation options you'll find within a mile.
How many hotels are there near Historic Main Street?
Expedia has 91 hotels and other accommodation options within a mile from Historic Main Street.
If I need to cancel the hotel reservation for my stay near Historic Main Street, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best options available near Historic Main Street.
What can I see and do near Historic Main Street?
Sights like First Missouri State Capitol Historic Site and Lewis & Clark Boathouse and Nature Center highlight some of the local culture. Create some family memories at Centene Community Ice Center and Kokomo Joe's Family Fun Center. At Hollywood Casino Amphitheatre, Missouri Artists on Main and Historic Aircraft Restoration Museum, you'll experience some of the local culture.