Clarksdale Holiday Rentals, Mississippi: Private House Rentals

A red electric guitar leaning against a speaker in a room with a piano in the background.

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Our top choices for Clarksdale hotels

A two-story brick building with large windows and a green door, featuring outdoor seating and a signboard.

A dining area with a table and four chairs, a potted plant, and a lamp.

A spacious lobby with a green door, a beige sofa, a wooden coffee table, and a large window offering a view of the outside.

A window with the text "TRAVELERS HOTEL" and a reflection of a bar area with stools and a counter.

1. Travelers Hotel

Clarksdale

Suzanne

4.094.144 ₫

4.462.617 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel dining area with a large wooden table, multiple chairs, a television, and wall-mounted lights.

A reception desk with a wooden finish, a framed welcome sign, and a lamp.

A hotel room with a large bed, a bedside table with a lamp, a chair, a bench, and a patterned carpet.

A rectangular swimming pool with a blue interior, surrounded by a brick border and a metal railing.

2. Hampton Inn Clarksdale

Clarksdale

Judy

3.373.322 ₫

3.676.921 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with a sofa, armchairs, and a coffee table. Large windows with curtains provide a view of the outdoors.

A dining area with a table, chairs, a television, a cabinet, and a floral centerpiece.

A hotel room with two beds, a desk with a computer, a chair, a television, and two lamps.

A compact black refrigerator with a microwave on top, a small wooden table, and a potted plant.

3. Americas Best Value Inn & Suites Clarksdale

Clarksdale

Richard

2.070.541 ₫

2.256.913 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A lobby with patterned carpet, two sofas, a round coffee table, a plant, and a framed picture on the wall.

A hotel with a covered outdoor area, columns, and a clear sky.

A lobby with two armchairs, a round ottoman, a small table with two lamps, and a framed artwork on the wall.

A fitness room with an elliptical trainer, a treadmill, and a stationary bike.

4. Quality Inn Clarksdale

Clarksdale

Blu

2.079.413 ₫

2.266.560 ₫ total

includes taxes & fees

10 Nov - 11 Nov

A bar area with wooden bar stools and shelves with bottles and glasses.

A bar area with two leather barstools, a brick wall, a wooden cabinet with glassware, and a brick oven.

A modern lounge area with a flat-screen TV, ceiling fans, and guitars on the wall.

A shower area with three white shower curtains tied to a central rod, beige tiled walls, and a tiled floor.

5. Auberge Clarksdale Blues Hostel

Clarksdale

Brian

3.100.764 ₫

3.380.063 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A modern lobby with a staircase, a reception desk, and two abstract paintings on the wall.

A casino floor with blackjack tables, slot machines, and an ATM.

A hotel entrance with a covered area, a sign reading "Casino Entrance," and a well-maintained lawn.

A hotel room with two beds, a television, a desk, and a window with curtains.

6. Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination

Lula

Jeff

1.518.155 ₫

1.654.789 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with a wooden floor, a sofa, a coffee table, and a dining area visible through a glass door.

A spacious living area with a large fireplace, two sofas with side tables, and a coffee table.

A multi-story building with a sign reading "Cotton House."

A spacious room with large windows, a polished concrete floor, and multiple circular chandeliers.

7. Cotton House, Cleveland, a Tribute Portfolio Hotel

Cleveland

John

3.596.347 ₫

3.920.018 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A reception desk with a wooden counter, a computer monitor, and various items on the desk.

A hotel room with two beds, a desk, a television, and a door.

A dining area with a wooden table and chairs, a kitchen in the background, and green walls.

A parking lot with several cars, a covered walkway, and a building with brick walls and windows.

8. Delta Inn West Helena US 49 AR

West Helena

Jennifer

1.540.157 ₫

1.917.499 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A modern restaurant with brick walls, multiple seating areas, and pendant lighting.

A modern hotel lobby with a dining area, sofas, and a large window offering a view.

A modern kitchen with a black marble island, a brick wall, and a large window.

A spacious living room with a fireplace, modern furniture, and a chandelier.

9. Lyric Hotel West End, Trademark Collection by Wyndham

Cleveland

Britiani

3.236.712 ₫

3.528.016 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A buffet with labeled sections for omelets and cheese.

A hotel room with a dining table, four chairs, a sofa, a TV, and a large window with curtains.

A hotel lobby with a brown leather sofa, two striped pillows, a floor lamp, and two floral paintings on the wall.

A hotel lobby with a reception desk, chairs, and a hallway leading to the exit.

10. Holiday Inn Express Hotel & Suites Cleveland by IHG

Cleveland

Linda

2.976.775 ₫

3.244.684 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A bedroom with a bed, a nightstand, a dresser, and a wall-mounted TV.

A motel with a covered parking area and a gas station in the background.

A Wendy's restaurant with a 6 Motel sign nearby.

A bathroom with a white countertop, a sink, a mirror, and a towel rack.

11. Motel 6 Cleveland, MS - Delta State University

Cleveland

Richelle

1.898.819 ₫

2.069.840 ₫ total

includes taxes & fees

19 Oct - 20 Oct

A hotel room with a bed, a dresser, a television, and a small refrigerator.

A hotel room with two beds, a desk, a mirror, and a window with curtains.

A motel with a red exterior, a covered parking area, and a small outdoor seating area.

A bathroom with a bathtub, toilet, and shower curtain.

12. c towninn and suites

Cleveland

Angela

1.280.713 ₫

1.395.978 ₫ total

includes taxes & fees

19 Oct - 20 Oct

A motel with a row of rooms, a parking lot, and a clear sky.

13. Sands Motel West Helena US 49 AR

West Helena

1.423.015 ₫

1.629.482 ₫ total

includes taxes & fees

25 Oct - 26 Oct

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Stay near popular Clarksdale attractions

Ground Zero Blues Club

Step into this authentic juke joint co-owned by Morgan Freeman for soulful Delta blues performances. Savour Southern comfort food while listening to emerging and established artists in a memorabilia-filled setting.

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Delta Blues Museum

9.0/10 (83 reviews)

The world's first blues museum preserves the rich legacy of this uniquely American art form. Explore Muddy Waters' restored cabin and immerse yourself in the soulful sounds that shaped modern music.

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Hambone Art Gallery

9.0/10 (22 reviews)

At Hambone Art Gallery, Stan Street's vibrant artwork mingles with live blues music. Experience Clarksdale's cultural heartbeat Tuesdays when local musicians transform the gallery into an intimate concert venue.

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The Crossroads

At this legendary crossroads, Robert Johnson reportedly sold his soul to the devil for blues mastery. Stand among the three guitar monuments where Highway 61 meets 49 and feel the weight of musical history.

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The Holy Moly Theatre

7.8/10 (13 reviews)

This historic 1923 Masonic temple now hosts intimate performances celebrating the Mississippi Delta's rich artistic heritage. Experience local talent amid architectural charm during evening shows of music and theatre.

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Hopson Hospitality

Learn about the local history of Clarksdale when you take a trip to Hopson Hospitality. You can enjoy the restaurants while in the area.

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Red's Lounge

8.6/10 (56 reviews)

Step inside one of Mississippi's last authentic juke joints where blues legends perform mere feet away. Red's intimate, no-frills atmosphere delivers raw Delta blues in its purest form—bring cash for the cover charge.

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New Roxy

8.4/10 (20 reviews)

This historic open-air venue celebrates Mississippi's blues heritage with live performances against rustic brick walls. Experience authentic Delta culture under the stars during the Deep Blues Festival in October.

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Learn more about Clarksdale

The birthplace of blues music welcomes visitors with live performances at historic juke joints like Ground Zero Blues Club. Explore the Delta Blues Museum by day, then follow locals to hole-in-the-wall spots where musicians jam until dawn.

See all hotels in Clarksdale

A blue guitar with road signs 61 and 49 mounted on top.

Top Clarksdale Hotel Reviews

Lyric Hotel West End, Trademark Collection by Wyndham

10/10 Excellent

"Great staff"

Delta Inn West Helena US 49 AR

10/10 Excellent

"Enjoyed stay."

Quality Inn Clarksdale

10/10 Excellent

"Two story structure with no elevator & vending was lacking. Other then those 2 negatives, the stay was great. Staff was friendly & attentive. Room was clean with enough towels. Rooms cleaned daily. Most things in the room were in working condition-had to learn how to operate the tv & a lamp was out. Checking in & out was fast."

Holiday Inn Express Hotel & Suites Cleveland by IHG

8/10 Good

"The staff was friendly and helpful. Breakfast was great! I didn’t give 5 stars in cleanliness because they were in the midst of a remodel. Otherwise my stay was great."

Quality Inn & Suites West Helena

8/10 Good

"Decent place to stay. Very nice staff."

Auberge Clarksdale Blues Hostel

10/10 Excellent

"My first time in a hostel and was sort of dreading it, but it was lovely. Shared bathroom was more like a locker room. Great location to walk everywhere."

Quality Inn Cleveland, MS

10/10 Excellent

"Pretty good breakfast! Nice staff.."

Walk Downtown: Home w/ Yard in Clarksdale

10/10 Excellent

"Neat old house, in a cool town if you like the blues."

More cheap stays in Clarksdale

Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination

777 Isle of Capri Parkway Lula MS

1.518.155 ₫

1.654.789 ₫ total

1 Nov - 2 Nov

includes taxes & fees

Delta Inn West Helena US 49 AR

1207 Us 49 West Helena AR

1.540.157 ₫

1.917.499 ₫ total

18 Oct - 19 Oct

includes taxes & fees

6.6/10 (427 reviews)

Motel 6 Cleveland, MS - Delta State University

721 N Davis Ave Cleveland MS

1.898.819 ₫

2.069.840 ₫ total

19 Oct - 20 Oct

includes taxes & fees

Quality Inn Clarksdale

818 South State Street Clarksdale MS

2.079.413 ₫

2.266.560 ₫ total

10 Nov - 11 Nov

includes taxes & fees

7.2/10 Good! (788 reviews)

Holiday Inn Express Hotel & Suites Cleveland by IHG

808 N Davis Ave Cleveland MS

2.976.775 ₫

3.244.684 ₫ total

15 Nov - 16 Nov

includes taxes & fees

7.8/10 Good! (1,000 reviews)

Hampton Inn Clarksdale

15000 New Africa Rd Clarksdale MS

3.373.322 ₫

3.676.921 ₫ total

1 Nov - 2 Nov

includes taxes & fees

Hotels in Clarksdale with star rating

Frequently asked questions

What's the seasonal weather in Clarksdale?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 9°C. Average annual precipitation for Clarksdale is 1403 mm.

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More ways to book

Book Hotels in Clarksdale on Expedia.com

Find hotels in Clarksdale, MS from 1.395.978 ₫

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Clarksdale

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Clarksdale hotels

1. Travelers Hotel

2. Hampton Inn Clarksdale

3. Americas Best Value Inn & Suites Clarksdale

4. Quality Inn Clarksdale

5. Auberge Clarksdale Blues Hostel

6. Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination

7. Cotton House, Cleveland, a Tribute Portfolio Hotel

8. Delta Inn West Helena US 49 AR

9. Lyric Hotel West End, Trademark Collection by Wyndham

10. Holiday Inn Express Hotel & Suites Cleveland by IHG

11. Motel 6 Cleveland, MS - Delta State University

12. c towninn and suites

13. Sands Motel West Helena US 49 AR

Stay near popular Clarksdale attractions

Ground Zero Blues Club

Delta Blues Museum

Hambone Art Gallery

The Crossroads

The Holy Moly Theatre

Hopson Hospitality

Red's Lounge

New Roxy

Learn more about Clarksdale

Top Clarksdale Hotel Reviews

Lyric Hotel West End, Trademark Collection by Wyndham

Delta Inn West Helena US 49 AR

Quality Inn Clarksdale

Holiday Inn Express Hotel & Suites Cleveland by IHG

Quality Inn & Suites West Helena

Auberge Clarksdale Blues Hostel

Quality Inn Cleveland, MS

Walk Downtown: Home w/ Yard in Clarksdale

More cheap stays in Clarksdale

Isle Casino Hotel Lula Hotel & Casino - A Caesars Rewards Destination

Delta Inn West Helena US 49 AR

Motel 6 Cleveland, MS - Delta State University

Quality Inn Clarksdale

Holiday Inn Express Hotel & Suites Cleveland by IHG

Hampton Inn Clarksdale

Hotels in Clarksdale with star rating

Frequently asked questions

Explore a world of travel with Expedia

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