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Find hotels in De Soto, MO from 1.361.540 ₫
Go beyond your typical stay in De Soto
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Top 10 De Soto hotels and places to stay
Our top choices for De Soto hotels

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
8.0 out of 10, Very good, (837)
The price is 2.666.921 ₫
3.049.624 ₫ total
includes taxes & fees
13 Sept - 14 Sept

Corner George Inn Bed & Breakfast
Corner George Inn Bed & Breakfast
9.0 out of 10, Wonderful, (153)
The price is 3.389.523 ₫
3.761.693 ₫ total
includes taxes & fees
2 Sept - 3 Sept

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
9.4 out of 10, Exceptional, (672)
The price is 3.111.188 ₫
3.557.643 ₫ total
includes taxes & fees
7 Sept - 8 Sept

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
9.4 out of 10, Exceptional, (150)
The price is 3.687.312 ₫
4.291.850 ₫ total
includes taxes & fees
7 Sept - 8 Sept

Postcard Cabins St. Francois
Postcard Cabins St. Francois
10.0 out of 10, Exceptional, (30)
The price is 2.345.417 ₫
3.516.123 ₫ total
includes taxes & fees
8 Sept - 9 Sept

The Conner House B&B
The Conner House B&B
10.0 out of 10, Exceptional, (16)
The price is 4.117.656 ₫
4.569.775 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Photo by Jessica King
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Top De Soto Hotel Reviews
More cheap stays in De Soto
More cheap stays in De Soto

Pear Tree Inn St. Louis Arnold
1201 Drury Ln, Arnold, MO
The price is 2.371.506 ₫ per night from 3 Sept to 4 Sept
2.371.506 ₫
2.741.239 ₫ total
3 Sept - 4 Sept
includes taxes & fees
Hotels in De Soto with star rating
Hotels in De Soto with star rating

2 Star Hotels
20 properties
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Accommodation near De Soto attractions
- Hotels near Mississippi River
- Hotels near Meramec State Park
- Hotels near Meramec River
- Hotels near Bonne Terre Mine
- Hotels near Hawn State Park
- Hotels near Big River
- Hotels near St. Francois State Park
- Hotels near Pickle Springs Natural Area
- Hotels near Washington State Park
- Hotels near Villa Antonio Winery
- Hotels near Mastodon State Historic Site
- Hotels near Fort de Chartes
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Hotels near De Soto Airports
Hotels Near De Soto, Missouri
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