Find hotels in East Prairie, MO from 1.481.947 ₫

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Our top choices for East Prairie hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,004 reviews)
"Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay."
United States
Nicole
The price is 2.469.211 ₫
2.838.844 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Drury Inn & Suites Sikeston, MO

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (731 reviews)
"Clean room and easy access to room"
United States
Anne
The price is 1.457.778 ₫
1.661.503 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,003 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is 1.875.558 ₫
2.137.667 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Best Western Plus Sikeston

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (551 reviews)
"Roaches!"
United States
Teresa
The price is 1.347.754 ₫
1.600.491 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Country Hearth Inn & Suites Union City

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.2 out of 10, Wonderful, (311 reviews)
"Rooms were spotless and comfortable. The bathroom had all the amenities. Great view. Awesome buffet breakfast to wake up to. "
United States
Rickey Smith
The price is 2.732.288 ₫
3.244.592 ₫ total
includes taxes & fees
6 Feb - 7 Feb
Holiday Inn Express & Suites Union City by IHG

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (332 reviews)
"The rooms are big and the property is spotless!"
United States
debbie
The price is 2.121.464 ₫
2.519.239 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Sleep Inn at Discovery Park of America

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1,004 reviews)
"Very clean, very friendly! We will be staying again. "
United States
Beth
The price is 1.970.062 ₫
2.264.823 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Pear Tree Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (463 reviews)
"Very clean and super friendly staff!"
United States
Katherine
The price is 2.659.252 ₫
3.010.939 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Hampton Inn Sikeston

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (43 reviews)
"Great hotel, great staff"
United States
Dmitry
The price is 1.465.922 ₫
1.674.450 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Super 8 By Wyndham Marston

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (734 reviews)
"Parking was good, staff was great "
United States
Corey
New Orleans Inn Portageville

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,001 reviews)
"Rooms need updated and the breakfast didn’t have much to offer."
United States
Bonnie
The price is 1.652.446 ₫
1.883.376 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Days Inn and Suites by Wyndham Sikeston

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (491 reviews)
"Nice room"
Mexico
José Ricardo
The price is 1.764.165 ₫
2.094.945 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Quality Inn Union City US 51

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (620 reviews)
"Staff was great! Room was nice. "
United States
Lana
The price is 1.631.429 ₫
1.810.335 ₫ total
includes taxes & fees
16 Feb - 17 Feb
Super 8 by Wyndham Charleston/Sikeston East MO

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (49 reviews)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is 2.653.371 ₫
3.004.279 ₫ total
includes taxes & fees
29 Jan - 30 Jan
Fairfield Inn & Suites by Marriott Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (446 reviews)
"Stay was excellent "
United States
Kourtney
The price is 2.758.560 ₫
3.123.380 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express & Suites Sikeston Southwest by IHG

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (275 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
The price is 2.164.730 ₫
2.402.417 ₫ total
includes taxes & fees
19 Jan - 20 Jan
Quality Inn Cairo I-57

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (284 reviews)
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is 2.210.705 ₫
2.519.651 ₫ total
includes taxes & fees
21 Jan - 22 Jan
Comfort Inn & Suites Sikeston I-55

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (168 reviews)
"Staff was great. Room was ready and clean. "
United States
Robert
The price is 2.865.224 ₫
3.402.453 ₫ total
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn Union City

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.0 out of 10, Good, (464 reviews)
"I had a decent stay near Reelfoot Lake — definitely about a 2-star hotel. I appreciated that the room had tile floors instead of carpet, though they weren’t very clean or well-kept. The door barely locked, which was a bit concerning, and there were dogs barking throughout the night, making it hard to rest. That said, I was thankful to find a place at the last minute, and it served its purpose for a quick overnight stay."
United States
Allison
The price is 1.362.151 ₫
1.563.067 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Reelfoot Lake Inn

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (11 reviews)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is 2.992.267 ₫
3.387.994 ₫ total
includes taxes & fees
25 Jan - 26 Jan
TownePlace Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

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Frequently asked questions

What's the weather like in East Prairie?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.