East Prairie Holiday Rentals, Missouri: Private House Rentals

A tree-lined landscape with a river and fields.

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Our top choices for East Prairie hotels

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

1. Drury Inn & Suites Sikeston, MO

Sikeston

Tim

2.434.153 ₫

2.798.667 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

2. Hampton Inn Sikeston

Sikeston

Lori

2.729.649 ₫

3.104.293 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A breakfast buffet counter with a bakery section and a display for breakfast items.

An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.

A kitchenette with a coffee machine, a kettle, and storage shelves.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

2.512.106 ₫

2.856.893 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

4. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

1.799.652 ₫

2.051.155 ₫ total

includes taxes & fees

21 Oct - 22 Oct

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

5. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Roslyn

2.615.698 ₫

2.974.703 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

6. Best Western Plus Sikeston I-55

Sikeston

Shelley

2.066.142 ₫

2.354.886 ₫ total

includes taxes & fees

8 Nov - 9 Nov

A building with a fountain and flower beds in front.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

7. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

1.721.958 ₫

1.927.847 ₫ total

includes taxes & fees

23 Oct - 24 Oct

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a counter, a flat-screen TV, and a window with blinds.

8. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

1.540.931 ₫

1.725.584 ₫ total

includes taxes & fees

21 Oct - 22 Oct

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

9. TownePlace Suites by Marriott Sikeston

Sikeston

Rubin

2.822.882 ₫

3.210.322 ₫ total

includes taxes & fees

29 Oct - 30 Oct

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

10. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

1.717.037 ₫

1.956.994 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A living room with two sofas, a coffee table, a TV, and a cabinet.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

11. Comfort Inn & Suites Sikeston I-55

Sikeston

Fred

2.051.122 ₫

2.337.767 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

A bathroom with a bathtub, toilet, and shower curtain.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

12. Country Yard Inn and Suite

Sikeston

William

1.513.220 ₫

1.800.354 ₫ total

includes taxes & fees

21 Oct - 22 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.

13. Eagle Inn Charleston

Charleston

Jackson

1.709.009 ₫

1.913.603 ₫ total

includes taxes & fees

21 Oct - 22 Oct

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

A hotel with a central entrance, multiple parking spaces, and a well-lit facade.

A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.

A modern kitchen with a stone backsplash, a dining area with red chairs, and a red accent wall with a framed picture.

14. Super 8 By Wyndham Marston

Marston

Brenda

1.445.108 ₫

1.657.899 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel lobby with a reception desk, seating areas, and a large abstract art piece on the wall.

A modern meeting room with red and grey chairs, a large flat-screen TV, and a wooden cabinet with decorative items.

A modern office space with a long desk, two chairs, and a computer. There are multiple tables and chairs in the background, and a colorful striped artwork on the wall.

An indoor swimming pool with clear water, safety signs, and chairs around the pool.

15. Holiday Inn Express & Suites Union City by IHG

Union City

Kevin

3.055.964 ₫

3.628.957 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A reception area with a reception desk, two blue armchairs, a round table, and a glass door leading outside.

A modern building with a covered entrance, a nameplate, and a landscaped area with shrubs and a street lamp.

A large indoor swimming pool with a tiled floor, surrounded by seating areas and tables.

An outdoor patio area with a blue sectional sofa, an orange ottoman, and black metal chairs.

16. Sleep Inn at Discovery Park of America

Union City

Ben

1.884.338 ₫

2.237.651 ₫ total

includes taxes & fees

15 Nov - 16 Nov

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with a desk, chair, television, and a lamp.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

17. Quality Inn Cairo I-57

Cairo

Santiago

1.764.431 ₫

1.958.166 ₫ total

includes taxes & fees

13 Nov - 14 Nov

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A motel with a covered entrance, multiple rooms, and a parking lot.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

18. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Laura

1.479.294 ₫

1.686.025 ₫ total

includes taxes & fees

27 Oct - 28 Oct

A hotel dining area with a long counter, multiple tables, and chairs. There are curtains on the windows, a lamp, and a view of the outdoors.

A reception area with a wooden counter, a television, and a sign for 'Quality Inn by Marriott'.

A hotel room with a large bed, a desk, a chair, and a bedside table.

A hotel room with a dining area, a sofa set, a TV mounted on the wall, and a patterned carpet.

19. Quality Inn Union City US 51

Union City

Logan

1.739.051 ₫

2.065.123 ₫ total

includes taxes & fees

10 Nov - 11 Nov

An outdoor seating area with a fire pit, cushioned chairs, and a metal fence.

A Hampton Inn hotel with a modern design, featuring a well-lit entrance and a clear signage.

An indoor swimming pool with a no diving sign, lounge chairs, and a no diving sign at the bottom.

A modern hotel lobby with multiple seating areas, a kitchen in the background, and large windows with curtains.

20. Hampton Inn Union City

Union City

Melody

2.641.596 ₫

3.136.894 ₫ total

includes taxes & fees

1 Nov - 2 Nov

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Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

See properties

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artefacts tell the storey of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie

Top East Prairie Hotel Reviews

Super 8 By Wyndham Marston

8/10 Good

"Got there late and staff was very helpful. Room was clean and comfortable"

Comfort Inn & Suites Sikeston I-55

10/10 Excellent

"The room was nice"

Hampton Inn Sikeston

10/10 Excellent

"Every part of this stay was excellent, from check in to check out. Helpful and friendly staff, wonderful, clean and well furnished room, delicious breakfast. Highly recommend."

Hampton Inn Union City

10/10 Excellent

"Very clean Comfy beds Good variety of breakfast items"

Quality Inn Union City US 51

10/10 Excellent

"Awesome"

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"good, clean, affordable :)"

Sleep Inn at Discovery Park of America

8/10 Good

"Everything was nice. Bed very comfortable."

Reelfoot Lake Inn

8/10 Good

"Dated but descent."

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"Easy parking, our bathroom sink was leaning forward and we had to place our soap in the sink so it didn't slide on the floor."

More cheap stays in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

1.479.294 ₫

1.686.025 ₫ total

27 Oct - 28 Oct

includes taxes & fees

7/10 Good! (688 reviews)

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

1.540.931 ₫

1.725.584 ₫ total

21 Oct - 22 Oct

includes taxes & fees

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

1.717.037 ₫

1.956.994 ₫ total

1 Nov - 2 Nov

includes taxes & fees

Sleep Inn at Discovery Park of America

1111 BLue Heron Lane Union City TN

1.884.338 ₫

2.237.651 ₫ total

15 Nov - 16 Nov

includes taxes & fees

9.2/10 Wonderful! (438 reviews)

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

2.066.142 ₫

2.354.886 ₫ total

8 Nov - 9 Nov

includes taxes & fees

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

2.729.649 ₫

3.104.293 ₫ total

1 Nov - 2 Nov

includes taxes & fees

9/10 Wonderful! (646 reviews)

Hotels in East Prairie with star rating

Frequently asked questions

What's the weather like in East Prairie?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for East Prairie is 1522 mm.

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Book Hotels in East Prairie on Expedia.com

Find hotels in East Prairie, MO from 1.657.899 ₫

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in East Prairie

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for East Prairie hotels

1. Drury Inn & Suites Sikeston, MO

2. Hampton Inn Sikeston

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

4. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

5. Fairfield Inn & Suites by Marriott Sikeston

6. Best Western Plus Sikeston I-55

7. The Riverstone Hotel Charleston-Sikeston

8. Super 8 by Wyndham Charleston/Sikeston East MO

9. TownePlace Suites by Marriott Sikeston

10. Days Inn and Suites by Wyndham Sikeston

11. Comfort Inn & Suites Sikeston I-55

12. Country Yard Inn and Suite

13. Eagle Inn Charleston

14. Super 8 By Wyndham Marston

15. Holiday Inn Express & Suites Union City by IHG

16. Sleep Inn at Discovery Park of America

17. Quality Inn Cairo I-57

18. Super 8 by Wyndham Sikeston/Miner Area

19. Quality Inn Union City US 51

20. Hampton Inn Union City

Stay near popular East Prairie attractions

Big Oak Tree State Park

Learn more about East Prairie

Top East Prairie Hotel Reviews

Super 8 By Wyndham Marston

Comfort Inn & Suites Sikeston I-55

Hampton Inn Sikeston

Hampton Inn Union City

Quality Inn Union City US 51

Super 8 by Wyndham Sikeston/Miner Area

Sleep Inn at Discovery Park of America

Reelfoot Lake Inn

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

More cheap stays in East Prairie

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Charleston/Sikeston East MO

Days Inn and Suites by Wyndham Sikeston

Sleep Inn at Discovery Park of America

Best Western Plus Sikeston I-55

Hampton Inn Sikeston

Hotels in East Prairie with star rating

Frequently asked questions

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