The Best Hotels Closest to Guana Tolomato Matanzas National Estuarine Research Reserve in Ponte Vedra Beach - 2026 Updated Prices

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Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels

A modern breakfast area with a self-service counter, seating, and a beverage station.

A modern office space with a red and blue seating area, a computer desk, and a large window providing a view of the outdoors.

A modern hotel reception area with a curved desk, a large digital screen, and a seating area with blue cushions.

A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.

1. Tru By Hilton St. Augustine I-95

14.6 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jennifer

2.626.259 ₫

2.928.278 ₫ total

includes taxes & fees

18 Oct - 19 Oct

An indoor swimming pool with a wooden ceiling, clear pool area, and lounge chairs.

A hotel room with a bed, a desk, a chair, a window with a view, and a ceiling fan.

A modern hotel lobby with a reception desk, seating area, and large windows offering views of palm trees.

A modern cafe with seating areas, a coffee station, and a view of the outdoors.

2. Holiday Inn Express St. Augustine - Vilano Beach by IHG

12.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jonathan

3.272.724 ₫

3.960.775 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A spacious indoor area with hexagonal tile flooring, multiple seating arrangements including bar stools and tables, ceiling fans, and hanging pendant lights.

A modern bar area with a central bar, multiple seating options including bar stools and round tables, and a decorative ceiling.

A modern meeting room with a large table, six grey chairs, a chandelier, large windows with sheer curtains, and a patterned carpet.

A modern conference room with a long table, comfortable seating, a large TV screen, and a patterned carpet.

3. Hyatt Place St. Augustine/Vilano Beach

12.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Lisa

2.846.953 ₫

3.174.352 ₫ total

includes taxes & fees

5 Oct - 6 Oct

An aerial view of a beach with a long pier extending into the ocean, adjacent to a sandy shore with buildings and parked cars.

A hotel room with two beds, a desk, a large artwork on the wall, and a mirror.

An aerial view of a rectangular swimming pool with a tiled deck, surrounded by palm trees and a covered seating area.

A hotel with a pool, parking, and a view of the beach.

4. Ocean Breeze Inn

19.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Ashley

1.538.367 ₫

1.715.279 ₫ total

includes taxes & fees

8 Oct - 9 Oct

A spacious hotel lobby with a reception desk, seating area with sofas, and a large window providing natural light.

A modern hotel room with a bed, a sofa, a desk, and a round table.

A spacious dining area with a long table and multiple chairs, a bar area with shelves of bottles, and a seating area with a sofa and chairs.

A hotel with a covered entrance, multiple floors, and a sign indicating "Comfort Suites."

5. Comfort Suites St. Augustine Historic District Area

11.5 km from Guana Tolomato Matanzas National Estuarine Research Reserve

kenneth

2.537.660 ₫

2.829.490 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with white countertops, a stainless steel sink, a coffee maker, and a window with a view of the outside.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a coffee maker, and a pink chair.

A neatly made bed with a headboard, two bedside tables with lamps, a window with a view, and a wall with a tropical leaf mural.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a flat-screen TV, and a dining area with pink chairs.

6. Haleys Court Boutique Motel

12.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Megan

2.279.218 ₫

3.989.379 ₫ total

includes taxes & fees

5 Oct - 6 Oct

A spacious lobby with a marble floor, a reception desk, and a large wall mural.

A modern cafe interior with a central table, counter, and various food and drink dispensers.

A modern hotel with a covered entrance, palm trees, and a clear blue sky.

A pool area with lounge chairs and a staircase leading to a building.

7. Hampton Inn St. Augustine Downtown Historic District

13.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Francis

2.640.020 ₫

2.943.623 ₫ total

includes taxes & fees

12 Oct - 13 Oct

A waterfront promenade with a white railing, a bench, and a view of a cityscape across the water.

A dining table with breakfast items and a view of a waterfront.

A wooden deck with two white chairs and a small table, overlooking a calm body of water with boats and a bridge in the background.

A beachfront motel with multiple rooms, a pool, and a beach view.

8. Edgewater Inn

14.6 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Chuck

2.618.469 ₫

2.919.392 ₫ total

includes taxes & fees

5 Oct - 6 Oct

A reception area with leather sofas, a glass coffee table, and a reception desk.

A modern living room with a glass coffee table, black leather sofas, and a flat-screen TV mounted on the wall.

A hotel room with two beds, a small round table, a sofa, and a bathroom visible through an open door.

A building with a blue roof and a sign that reads "Regency Inn & Suites".

9. Regency Inn & Suites

19.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Joel

1.733.097 ₫

1.932.402 ₫ total

includes taxes & fees

7 Oct - 8 Oct

A reception area with a counter, seating, and a refrigerator.

A rectangular swimming pool with clear blue water, surrounded by a tiled deck and a fence.

A crowded beach with numerous people and parked cars.

A modern bathroom with a large mirror, a round mirror, and a black storage unit with shelves.

10. Rodeway Inn St. Augustine Historic District

11.6 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Kaley

1.321.363 ₫

1.473.320 ₫ total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a desk, a chair, a mirror, and artwork on the wall.

A restaurant interior with booths and tables, menu boards, and a coffee station.

A swimming pool with a fenced deck area, surrounded by palm trees and a building with multiple balconies.

11. Days Inn by Wyndham St. Augustine I-95/Outlet Mall

14.4 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Roberta

1.682.467 ₫

1.875.950 ₫ total

includes taxes & fees

5 Oct - 6 Oct

A hotel with a pool, a covered entrance, and a sign for 'City Express by Marriott.'

A modern hotel room with a wooden floor, a sofa, a small table, a chair, and a TV.

A hotel room with two beds, a TV, and artwork on the wall.

A modern hotel lobby with a reception desk, seating area, and a bookshelf.

12. City Express By Marriott St. Augustine

12.1 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Cathy

2.180.976 ₫

2.431.788 ₫ total

includes taxes & fees

7 Oct - 8 Oct

A waterfront marina with boats docked, a bridge, and a sunset over the water.

A fire feature with a view of a waterfront and a bridge in the background.

A dining table with two chairs, a wine glass, a rose, and a glass of beer.

A hotel with a sign reading "MARKER 8 HOTEL & MARINA".

13. Marker 8 Hotel & Marina

14.7 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Mary

3.719.996 ₫

4.147.788 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A balcony with two chairs and a table, overlooking a beach and buildings.

An aerial view of a fortified structure with a central courtyard, surrounded by walls and a moat.

A spacious lobby with a dining area, a seating area with a sofa and armchairs, and a balcony with decorative railings.

A kitchen with a white countertop, wooden cabinets, and a microwave. There are three wooden chairs with light-colored cushions. A painting of a coastal scene hangs above the counter.

14. Hampton Inn & Suites St. Augustine-Vilano Beach

12.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Sandra

2.533.567 ₫

2.824.927 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A wooden gazebo with a balcony, a staircase, and outdoor seating.

A spacious dining area with multiple tables and chairs, a kitchen in the background, and a large window with curtains.

A pool area with lounge chairs, a red umbrella, and palm trees.

A living room with a brown leather sofa, blue armchairs, a coffee table, and a TV on a wooden cabinet.

15. The Bayfront Inn

14.9 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Brittany

3.278.474 ₫

3.655.471 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A building with a covered porch, outdoor lighting, and greenery.

A swimming pool with a white fence, lounge chairs, and a blue canopy.

A two-story building with a white exterior and a brick staircase.

A bathroom with a wooden vanity, a sink, a mirror, a microwave, and a coffee maker.

16. Quality Inn St Augustine Historic District Area

11.8 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Weston

1.740.627 ₫

1.940.809 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A multi-story hotel with a waterfront view, featuring a reflective pool in front.

A spacious lobby with a modern bar area, seating arrangements, and a herringbone-patterned wall.

A poolside area with lounge chairs and a fire pit.

An outdoor patio with wicker furniture, a grill, and a view of the building's interior.

17. Homewood Suites by Hilton St. Augustine San Sebastian

14.8 km from Guana Tolomato Matanzas National Estuarine Research Reserve

William

2.960.517 ₫

3.300.977 ₫ total

includes taxes & fees

1 Nov - 2 Nov

A modern bar area with a counter, seating, and various amenities.

A store interior with shelves stocked with various products, a refrigerated display, and a 'market' sign on the wall.

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a fence.

A hotel lobby with a seating area, a kitchenette, a door, and a wall-mounted artwork.

18. Courtyard by Marriott St Augustine I-95

14.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

jonathan

1.964.177 ₫

2.190.057 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A hot tub with a metal ladder, surrounded by lounge chairs and a pool.

A hotel room with two beds, a painting on the wall, a lamp, and a wooden floor.

A restaurant interior with tables and chairs, a large wall with multilingual welcome signs, and a ceiling with recessed lighting.

A kitchen counter with a refrigerator, microwave, coffee maker, and various food items.

19. The Smart Stay Inn

14.4 km from Guana Tolomato Matanzas National Estuarine Research Reserve

sean

2.310.794 ₫

2.576.535 ₫ total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a striped sofa, yellow chairs, and a table.

A hotel with a modern design, featuring a prominent entrance and a sign indicating it is a Home 2 Suites by Hilton.

A modern hotel lobby with a sofa, chairs, a table, and a TV.

A hotel room with a sofa, a bedside table with a lamp, a bed with a headboard, and a wall with a patterned wallpaper.

20. Home2 Suites by Hilton St. Augustine I-95

14.1 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Sean

3.598.091 ₫

4.011.871 ₫ total

includes taxes & fees

8 Oct - 9 Oct

View all properties

Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve

Property	Property class	Guest rating
Tru By Hilton St. Augustine I-95	9.4 Exceptional 466 reviews	View
Holiday Inn Express St. Augustine - Vilano Beach by IHG	9.8 Exceptional 759 reviews	View
Hyatt Place St. Augustine/Vilano Beach	9.2 Wonderful 1,588 reviews	View
Ocean Breeze Inn	8.2 Very good 1,155 reviews	View
Comfort Suites St. Augustine Historic District Area	9.2 Wonderful 1,821 reviews	View

Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews

Other attractions near Guana Tolomato Matanzas National Estuarine Research Reserve

Guana Pine State Park and Wildlife Management Area

8.6/10 (9 reviews)

Explore the lovely green spaces of Guana Pine State Park and Wildlife Management Area and enjoy the golf courses in Ponte Vedra Beach. Wander the beautiful beaches and seaside in the area.

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South Ponte Vedra Beach

Why not spend a lazy afternoon at South Ponte Vedra Beach during your trip to Ponte Vedra Beach?

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Guana River Wildlife Management Area

You can take time to visit Guana River Wildlife Management Area during your travels to Ponte Vedra Beach.

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Water + Stone Gallery

You can browse the exhibits at Water + Stone Gallery, a museum with a storied past, during your travels to St. Augustine. Wander the beautiful beaches and seaside in the area.

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Castle Otttis

8.8/10 (8 reviews)

Castle Otttis is just one of the places to see in St. Augustine, so why not enjoy the other things to explore during your travels? Wander the beautiful beaches and seaside in the area.

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Usina Beach

Why not spend a care-free afternoon at Usina Beach during your travels in Ponte Vedra Beach?

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The Schoolyard

The Schoolyard is just one of the places to see in Nocatee, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around Guana Tolomato Matanzas National Estuarine Research Reserve?

Guana Tolomato Matanzas National Estuarine Research Reserve is located in a family-friendly area of Ponte Vedra Beach known for its interesting historical sites and major shopping area. If you're looking for a convenient place to stay, take a look at the 49 hotels and other accommodation options you'll find within a mile.

How many hotels should I expect to find close to Guana Tolomato Matanzas National Estuarine Research Reserve?

Expedia has 49 hotels and other accommodation options within a mile from Guana Tolomato Matanzas National Estuarine Research Reserve.

If I need to cancel the hotel reservation for my stay near Guana Tolomato Matanzas National Estuarine Research Reserve, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals available near Guana Tolomato Matanzas National Estuarine Research Reserve.

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Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels

1. Tru By Hilton St. Augustine I-95

2. Holiday Inn Express St. Augustine - Vilano Beach by IHG

3. Hyatt Place St. Augustine/Vilano Beach

4. Ocean Breeze Inn

5. Comfort Suites St. Augustine Historic District Area

6. Haleys Court Boutique Motel

7. Hampton Inn St. Augustine Downtown Historic District

8. Edgewater Inn

9. Regency Inn & Suites

10. Rodeway Inn St. Augustine Historic District

11. Days Inn by Wyndham St. Augustine I-95/Outlet Mall

12. City Express By Marriott St. Augustine

13. Marker 8 Hotel & Marina

14. Hampton Inn & Suites St. Augustine-Vilano Beach

15. The Bayfront Inn

16. Quality Inn St Augustine Historic District Area

17. Homewood Suites by Hilton St. Augustine San Sebastian

18. Courtyard by Marriott St Augustine I-95

19. The Smart Stay Inn

20. Home2 Suites by Hilton St. Augustine I-95

Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve

Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews

Other attractions near Guana Tolomato Matanzas National Estuarine Research Reserve

Guana Pine State Park and Wildlife Management Area

South Ponte Vedra Beach

Guana River Wildlife Management Area

Water + Stone Gallery

Castle Otttis

Usina Beach

The Schoolyard

Frequently asked questions

Explore a world of travel with Expedia