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19 Dec - 20 Dec
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20 Dec - 21 Dec
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19 Dec - 21 Dec
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Our top choices for Texas Medical Center hotels

Sun deck
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center
8.4 out of 10, Very good, (1765)
"Loved the room, clean, friendly staff. Would reccomend :)"
United States
Rolando
The price is 2.264.917 ₫
2.680.489 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Hilton Houston Plaza/Medical Center
Lobby
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (3604)
"Great hotel I would definitely stay again"
United States
Newassa
The price is 2.918.081 ₫
3.414.153 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Blossom Hotel Houston, Curio Collection by Hilton
Daily buffet breakfast for a fee
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
Texas Medical Center
8.4 out of 10, Very good, (477)
"Solid hotel and amenities"
United States
Kenneth
The price is 2.358.630 ₫
2.759.596 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Lobby
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (2195)
"Comfortable room and nice breakfast in close proximity to Houston’s medical center. "
United States
Stephen
The price is 2.886.427 ₫
3.395.018 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hyatt Place Houston Medical Center
Reception
InterContinental Houston by IHG

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1004)
"Very clean room very polite staff"
United States
David
The price is 3.647.980 ₫
4.794.617 ₫ total
includes taxes & fees
24 Dec - 25 Dec
InterContinental Houston by IHG
Lobby lounge
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center
9.0 out of 10, Wonderful, (1001)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
United States
Elena
The price is 3.557.689 ₫
4.997.165 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Houston Marriott Medical Center/Museum District
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1017)
"Excellent breakfast and bar"
United States
Misty
The price is 3.403.298 ₫
4.236.084 ₫ total
includes taxes & fees
20 Dec - 21 Dec
The Westin Houston Medical Center/Museum District
Lobby
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center
9.2 out of 10, Wonderful, (1197)
"We were here for a rugby tournament and the staff kept up with everything very well"
United States
Jessica Lynn
The price is 2.886.427 ₫
3.395.018 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hyatt House Houston Medical Center
Terrace/patio
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (1001)
"Clean room and nice staff"
Canada
Guillermo
The price is 2.568.696 ₫
3.005.374 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn Houston Medical Center, TX
Terrace/patio
Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (565)
"Everything was good "
United States
cheryl
The price is 3.000.410 ₫
3.510.481 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Home2 Suites by Hilton Houston Medical Center, TX
Free self-parking
Americas Best Value Inn NRG Park Medical Center

Americas Best Value Inn NRG Park Medical Center

Americas Best Value Inn NRG Park Medical Center
2.0 star property
Texas Medical Center
7.8 out of 10, Good, (848)
"I liked the stay. This guy Shashank at the front desk is very sweet n nice. Everything thing was good."
United States
shiva
The price is 1.776.870 ₫
2.079.070 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Americas Best Value Inn NRG Park Medical Center
Free daily buffet breakfast
Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center
8.4 out of 10, Very good, (1002)
"Breakfast was good the place was comfortable "
United States
Elton
The price is 2.568.696 ₫
3.019.499 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Hampton Inn & Suites Houston Medical Center NRG Park
Desk, laptop workspace, iron/ironing board, cots/infant beds
Residence Inn by Marriott Houston Medical Center/NRG Park

Residence Inn by Marriott Houston Medical Center/NRG Park

Residence Inn by Marriott Houston Medical Center/NRG Park
3.0 star property
Texas Medical Center
9.4 out of 10, Exceptional, (505)
"Spacious, clean room and nice complementary breakfast "
United States
Karen
The price is 3.766.964 ₫
4.407.349 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Residence Inn by Marriott Houston Medical Center/NRG Park
Lobby
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
Texas Medical Center
5.8 out of 10, (1002)
"Room was very large…"
United States
Veronica
The price is 1.634.457 ₫
1.920.072 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston
4.0 star property
Houston Central Business District, 7 km from Texas Medical Center
8.4 out of 10, Very good, (3953)
"Rooms were great and the staff was absolutely amazing. "
United States
Elmer
The price is 2.092.310 ₫
2.448.003 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Club Quarters Hotel Downtown, Houston
Exterior
Hampton Inn & Suites Houston-Bush Intercontinental Aprt

Hampton Inn & Suites Houston-Bush Intercontinental Aprt

Hampton Inn & Suites Houston-Bush Intercontinental Aprt
3.0 star property
28 km from Texas Medical Center
8.8 out of 10, Excellent, (1716)
"Nice hotel, the staff was very friendly "
United States
Debra
The price is 2.230.959 ₫
2.624.054 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Exterior
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria
4.0 star property
The Galleria, 7.4 km from Texas Medical Center
8.4 out of 10, Very good, (1470)
"Wonderful hotel!"
United States
Debbie
The price is 2.927.217 ₫
3.424.845 ₫ total
includes taxes & fees
23 Dec - 24 Dec
The Royal Sonesta Houston Galleria
Exterior
Hilton Americas-Houston

Hilton Americas-Houston

Hilton Americas-Houston
4.0 star property
6.5 km from Texas Medical Center
9.4 out of 10, Exceptional, (1608)
"Great hotel. Lively bar, great breakfast, friendly staff, nice room, close to everything. "
United States
Thomas
The price is 3.657.639 ₫
4.332.100 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hilton Americas-Houston
City view
Hyatt Regency Houston Downtown

Hyatt Regency Houston Downtown

Hyatt Regency Houston Downtown
4.0 star property
Houston Central Business District, 6.6 km from Texas Medical Center
9.2 out of 10, Wonderful, (1095)
"Great staff and nice room. "
United States
Nikiesha
The price is 3.922.276 ₫
4.750.955 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hyatt Regency Houston Downtown
Outdoor pool
Tru by Hilton Houston Webster NASA

Tru by Hilton Houston Webster NASA

Tru by Hilton Houston Webster NASA
2.5 star property
31 km from Texas Medical Center
9.0 out of 10, Wonderful, (1002)
"The staff was super nice and the location worked great for us! "
Mexico
Valeria
The price is 2.029.054 ₫
2.373.993 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Tru by Hilton Houston Webster NASA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Texas Medical Center

Find the best Texas Medical Center areas for the activities you enjoy most.
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Jesse H. Jones Hall to Houston City Hall – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Northside

While you're in Northside, take in top sights like The Heights Theater or Greenspoint Mall, and hop on the metro to see more of the city at Northline Transit Center/HCC Station or Melbourne/North Lindale Station.

Houston Heights

You'll enjoy the coffee shops and live music in Houston Heights. You might want to make time for a stop at The Heights Theater or Artcar Museum.

Menil Collection featuring interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Top Texas Medical Center Hotel Reviews

Frequently asked questions

What is Texas Medical Center like?
Texas Medical Center is a neighbourhood that travellers like for its museums, shopping and zoo. Consider a visit to Houston Zoo as part of your Texas Medical Center travel plans.
How many hotels can I expect to find in the Texas Medical Center area?
Expedia has 184 hotels and other accommodation options in Texas Medical Center to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in Texas Medical Center, will I receive a refund?
Yes, you'll find most hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the best deals available in Texas Medical Center.
What can I see and do in this Houston neighbourhood?
Houston Zoo is an attraction you might want to check out while you're in Texas Medical Center. While you're out sightseeing, NRG Stadium and Reckling Park are a couple of additional sights to visit in Houston.
How can I get around Texas Medical Center and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at TMC Transit Center, Dryden/TMC Station or Smith Lands Station.