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Our top choices for South Central Houston hotels

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1,884 reviews)
"Extremely helpful staff, excellent service. Location is convenient to everything."
United States
Lori
Hotel Zaza Houston Museum District

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
2.0 star property
South Central Houston
9.8 out of 10, Exceptional, (59 reviews)
"Great location will stay again "
United States
Jason
The price is 3.120.401 ₫
3.651.237 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Wanderstay Boutique Hotel

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (497 reviews)
"We had dinner food was ok. "
United States
Lisa
The price is 2.185.581 ₫
2.557.130 ₫ total
includes taxes & fees
1 Feb - 2 Feb
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very good, (1,826 reviews)
"Good price, clean room, friendly and helpful staff."
United States
Kristoffer
The price is 2.634.255 ₫
3.112.552 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Hilton Houston Plaza/Medical Center

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,057 reviews)
"Great place to stay "
United States
Ernest
The price is 3.798.103 ₫
4.727.500 ₫ total
includes taxes & fees
18 Jan - 19 Jan
The Westin Houston Medical Center/Museum District

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (546 reviews)
"Lovely good sized room, clean and loved sitting down for a great breakfast at the large dining table with other guests "
United Kingdom
Shaun
The price is 4.701.614 ₫
5.500.887 ₫ total
includes taxes & fees
29 Jan - 30 Jan
La Maison in Midtown an urban B&B

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (202 reviews)
"I absolutely loved my stay here!!"
United States
Daniella
The price is 5.437.062 ₫
6.755.353 ₫ total
includes taxes & fees
19 Jan - 20 Jan
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Modern Cozy Home with King Bed

Modern Cozy Home with King Bed
3.5 star property
South Central Houston
9.2 out of 10, Wonderful, (24 reviews)
"Very spacious and close to just about everything. The view is amazing too"
United States
Brenden
The price is 5.673.456 ₫
11.628.484 ₫ total
includes taxes & fees
1 Feb - 2 Feb
Modern Cozy Home with King Bed

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,011 reviews)
"Love the intercontinental"
United States
Patrick
The price is 4.097.964 ₫
5.319.998 ₫ total
includes taxes & fees
18 Jan - 19 Jan
InterContinental Houston by IHG

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,000 reviews)
"Nice hotel"
United States
Robert Jeanmard
The price is 2.443.017 ₫
2.858.330 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Americas Best Value Inn Medical Center Downtown

Newly Built Modern 3 Bedroom Houston Home

Newly Built Modern 3 Bedroom Houston Home
2.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood. We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...
United States
robin
The price is 4.112.479 ₫
11.118.368 ₫ total
includes taxes & fees
18 Jan - 19 Jan
Newly Built Modern 3 Bedroom Houston Home

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,006 reviews)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
United States
Elena
The price is 3.759.094 ₫
5.234.785 ₫ total
includes taxes & fees
6 Feb - 7 Feb
Houston Marriott Medical Center/Museum District

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (190 reviews)
"Jj"
United States
diana
The price is 1.448.833 ₫
1.694.945 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Wanderstay Houston Hostel

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (890 reviews)
"Nice place to stay"
United States
Alexandra
The price is 4.070.705 ₫
4.762.725 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Hilton University of Houston

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
7.8 out of 10, Good, (46 reviews)
"Check in staff was friendly and room was clean."
United States
Alfredo
The price is 2.245.743 ₫
2.627.651 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Downtowner Inns - Houston Downtown

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (228 reviews)
"A classical Motel like in a Movie. The staff was really kind and helpful."
United Kingdom
Lisa-Maria
The price is 1.772.955 ₫
2.074.489 ₫ total
includes taxes & fees
19 Jan - 20 Jan
Southmore Boulevard Motel

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,005 reviews)
"Clean"
United States
William
The price is 1.536.298 ₫
1.804.737 ₫ total
includes taxes & fees
26 Jan - 27 Jan
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
3.0 star property
South Central Houston
The price is 5.632.218 ₫
17.342.126 ₫ total
includes taxes & fees
14 Jan - 15 Jan
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

The Oasis Checkmate HTX Rooftop

The Oasis Checkmate HTX Rooftop
3.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
United States
Veronica
The price is 7.296.316 ₫
17.996.840 ₫ total
includes taxes & fees
14 Jan - 15 Jan
The Oasis Checkmate HTX Rooftop

Downtown Houston 3BR Bachelorette Escape

Downtown Houston 3BR Bachelorette Escape
2.0 star property
South Central Houston
9.6 out of 10, Exceptional, (5 reviews)
"Everything was great. Look no further and book this property. "
United States
Iesheal
The price is 6.075.874 ₫
13.415.540 ₫ total
includes taxes & fees
16 Jan - 17 Jan
Downtown Houston 3BR Bachelorette Escape
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Top South Central Houston Hotel Reviews

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit Continental Club and Midtown Arts and Theater Center Houston as part of your South Central Houston travel plans.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1165 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and James Turrell's Twilight Epiphany Skyscape. Continental Club and Midtown Arts and Theater Center Houston are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station.