Photo by Greater Houston Convention and Visitors Bureau (photographer: Hugh Hargrave)

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Top Trending Hotels Near South Central Houston, Houston

Sun deck
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 star property
South Central Houston
8.4 out of 10, Very good, (1711)
"Clean rooms, comfortable bed, & friendly staff"
United States
Thomas
The price is 2.443.366 ₫
2.889.331 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton Houston Plaza/Medical Center
Exterior
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2.0 star property
South Central Houston
7.8 out of 10, Good, (29)
"Minimal breakfast/continental, small area to grab food. Rooms and facility very clean, looks newly renovated & well done. Front office/desk guy was very nice. Easy check in/out process. Convenient location for Midtown outting. I would stay here again & recommend this place. "
United States
Jalyn
The price is 2.254.806 ₫
2.638.255 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Downtowner Inns - Houston Downtown
Reception
InterContinental Houston by IHG

InterContinental Houston by IHG

4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1008)
"Clean room, excellent staff, kind and respectful."
United States
DIANA
The price is 2.923.705 ₫
3.948.175 ₫ total
includes taxes & fees
30 Nov - 1 Dec
InterContinental Houston by IHG
1 bedroom, premium bedding, pillow-top beds, minibar
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1830)
"Beautiful hotel, friendly staff. Would stay again! "
United States
Ashley
Hotel Zaza Houston Museum District
Daily buffet breakfast for a fee
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
South Central Houston
8.4 out of 10, Very good, (461)
"Staff was helpful in getting me back & forth to MD Anderson Cancer Hospital. "
United States
Patricia
The price is 3.016.957 ₫
3.529.840 ₫ total
includes taxes & fees
7 Dec - 8 Dec
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1022)
"Perfect location & amazing staff at the hotel"
United States
Orlando
The price is 3.611.250 ₫
4.494.923 ₫ total
includes taxes & fees
30 Nov - 1 Dec
The Westin Houston Medical Center/Museum District
Desk, free WiFi, bed sheets, alarm clocks
Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown

2.0 star property
South Central Houston
8.0 out of 10, Very good, (1012)
"Nice hotel"
United States
Robert Jeanmard
The price is 1.860.545 ₫
2.176.837 ₫ total
includes taxes & fees
2 Dec - 3 Dec
Americas Best Value Inn Medical Center Downtown
Lobby
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
South Central Houston
5.8 out of 10, (1007)
"Great receptionist. Clean room. Perfect location to access Md Anderson. "
United States
Rebecca
The price is 2.135.868 ₫
2.506.395 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1001)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
United States
Elena
The price is 3.564.446 ₫
5.006.657 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Houston Marriott Medical Center/Museum District
Interior
Wanderstay Houston Hostel

Wanderstay Houston Hostel

2.0 star property
South Central Houston
8.4 out of 10, Very good, (188)
"This is an amazing place to stay."
United States
Darius
The price is 1.582.320 ₫
1.851.314 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Wanderstay Houston Hostel
Exterior
La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B

3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (539)
"great neighborhood, friendly staff, and delicious breakfast"
United States
Anna
The price is 4.720.588 ₫
5.523.089 ₫ total
includes taxes & fees
7 Dec - 8 Dec
La Maison in Midtown an urban B&B
Outdoor pool
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (201)
" Beautiful relaxing love this place best I seen thank you"
United States
James
The price is 5.459.004 ₫
6.782.615 ₫ total
includes taxes & fees
29 Nov - 30 Nov
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Premium bedding, down duvets, pillow-top beds, in-room safe
Hilton University of Houston

Hilton University of Houston

3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (884)
"Nice place to stay"
United States
Alexandra
The price is 3.870.882 ₫
4.528.932 ₫ total
includes taxes & fees
4 Dec - 5 Dec
Hilton University of Houston
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout curtains, free WiFi
Southmore Boulevard Motel

Southmore Boulevard Motel

2.0 star property
South Central Houston
5.4 out of 10, (224)
"A classical Motel like in a Movie. The staff was really kind and helpful."
United Kingdom
Lisa-Maria
The price is 1.424.088 ₫
1.666.183 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Southmore Boulevard Motel
House | 3 bedrooms, Internet
Newly Built Modern 3 Bedroom Houston Home

Newly Built Modern 3 Bedroom Houston Home

2.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2)
"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood. We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...
United States
robin
The price is 3.651.508 ₫
10.270.523 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Newly Built Modern 3 Bedroom Houston Home
House | 4 bedrooms, desk, iron/ironing board, Internet
Paradise Palace Best Rooftop in HTX w Hot Tub

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
South Central Houston
Paradise Palace Best Rooftop in HTX w Hot Tub
Comfort Townhome | Private kitchen | Full-sized fridge, microwave, oven, dishwasher
Modern Cozy Home with King Bed

Modern Cozy Home with King Bed

3.5 star property
South Central Houston
9.4 out of 10, Exceptional, (22)
"Very spacious and close to just about everything. The view is amazing too"
United States
Brenden
The price is 3.560.220 ₫
9.176.139 ₫ total
includes taxes & fees
30 Nov - 1 Dec
Modern Cozy Home with King Bed
House | 4 bedrooms, soundproofing, bed sheets
Posh Dtwn Midtown Home w Stunning Roof-topterrace

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
South Central Houston
Posh Dtwn Midtown Home w Stunning Roof-topterrace
House | 3 bedrooms, Internet
Downtown Houston 3BR Bachelorette Escape

Downtown Houston 3BR Bachelorette Escape

2.0 star property
South Central Houston
9.6 out of 10, Exceptional, (5)
"Everything was great. Look no further and book this property. "
United States
Iesheal
The price is 2.642.159 ₫
9.089.584 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Downtown Houston 3BR Bachelorette Escape
House | 4 bedrooms, desk, soundproofing, iron/ironing board
The Oasis Checkmate HTX Rooftop

The Oasis Checkmate HTX Rooftop

3.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
United States
Veronica
The price is 8.342.117 ₫
18.757.665 ₫ total
includes taxes & fees
30 Nov - 1 Dec
The Oasis Checkmate HTX Rooftop
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
Discovery Green showing city views, modern architecture and a high-rise building

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Jesse H. Jones Hall to Houston City Hall – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection featuring interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Houston Heights

You'll enjoy the coffee shops and live music in Houston Heights. You might want to make time for a stop at The Heights Theater or Artcar Museum.

Top South Central Houston Hotel Reviews

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel

10/10 Excellent
"Very friendly staff, and easy check in process."
Kate 1-night trip
Posted 9 days ago
Wanderstay Boutique Hotel

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Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit Continental Club and Midtown Arts and Theater Center Houston as part of your South Central Houston travel plans.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1141 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and James Turrell's Twilight Epiphany Skyscape. Continental Club and Midtown Arts and Theater Center Houston are some other stops worth a visit in the neighbourhood. Shape Community Center, Project Row Houses and H&PE Arena are just a few of the places to visit in and around South Central Houston. Eldorado Ballroom and Barbara Jordan & Mickey Leland Archives are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station.