Search Hotels in South Central Houston, Houston

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Our top choices for South Central Houston hotels

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
8.4 out of 10, Very good, (70 reviews)
"great stay "
United States
Jordan
The price is 2.487.955 ₫
2.910.907 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Downtowner Inns - Houston Downtown

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very good, (1,857 reviews)
"Always a great stay at this hotel with good staff nice rooms and good food "
United States
Diane
The price is 2.604.099 ₫
3.077.204 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Hilton Houston Plaza/Medical Center

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (535 reviews)
"Room accommodations for disability, clean, comfortable beds and bedding, and having a resturant on site. Thank you for a great stay!"
United States
Judy
The price is 3.105.492 ₫
3.633.425 ₫ total
includes taxes & fees
30 Mar - 31 Mar
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,009 reviews)
"It was a quick stop for us and the room had everything we needed"
United States
Deiedra
The price is 2.592.711 ₫
3.033.472 ₫ total
includes taxes & fees
23 Mar - 24 Mar
Americas Best Value Inn Medical Center Downtown

Newly Built Modern 3 Bedroom Houston Home

Newly Built Modern 3 Bedroom Houston Home
2.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood. We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...
United States
robin
The price is 4.536.035 ₫
11.649.873 ₫ total
includes taxes & fees
24 Mar - 25 Mar
Newly Built Modern 3 Bedroom Houston Home

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
2.0 star property
South Central Houston
9.8 out of 10, Exceptional, (65 reviews)
"Great location will stay again "
United States
Jason
The price is 3.337.526 ₫
3.905.042 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Wanderstay Boutique Hotel

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,012 reviews)
"Very clean room & responsive staff!"
United States
ERIC
The price is 4.770.948 ₫
6.106.288 ₫ total
includes taxes & fees
6 Apr - 7 Apr
InterContinental Houston by IHG

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (204 reviews)
"I absolutely loved my stay here!!"
United States
Daniella
The price is 5.421.123 ₫
6.735.549 ₫ total
includes taxes & fees
23 Mar - 24 Mar
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (560 reviews)
"Good rooms and location, great staff!"
United States
Eugene
The price is 4.687.831 ₫
5.484.761 ₫ total
includes taxes & fees
17 Mar - 18 Mar
La Maison in Midtown an urban B&B

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,126 reviews)
"Excellent stay!"
United States
Travis
The price is 4.656.917 ₫
5.796.464 ₫ total
includes taxes & fees
29 Mar - 30 Mar
The Westin Houston Medical Center/Museum District

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,004 reviews)
"Rooms were tidy, clean and comfortable bedding. Staff extremely courteous and accommodating. "
United States
Linda
The price is 4.690.450 ₫
6.339.323 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Houston Marriott Medical Center/Museum District

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (908 reviews)
"Nice place to stay"
United States
Alexandra
The price is 3.925.284 ₫
4.592.583 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Hilton University of Houston

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1,914 reviews)
"Great location "
United States
Tolbert
Hotel Zaza Houston Museum District

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (231 reviews)
"A classical Motel like in a Movie. The staff was really kind and helpful."
United Kingdom
Lisa-Maria
The price is 1.532.056 ₫
1.792.506 ₫ total
includes taxes & fees
1 Apr - 2 Apr
Southmore Boulevard Motel

Downtown Houston 3BR Bachelorette Escape

Downtown Houston 3BR Bachelorette Escape
2.0 star property
South Central Houston
9.6 out of 10, Exceptional, (5 reviews)
"Everything was great. Look no further and book this property. "
United States
Iesheal
The price is 4.914.397 ₫
12.098.612 ₫ total
includes taxes & fees
18 Mar - 19 Mar
Downtown Houston 3BR Bachelorette Escape

Rodeway Inn & Suites Houston near Medical Center

Rodeway Inn & Suites Houston near Medical Center
2.0 star property
South Central Houston
6.0 out of 10, (502 reviews)
"Very economical. Great price for one night stay."
United States
AUGUSTIN
The price is 1.670.880 ₫
1.954.930 ₫ total
includes taxes & fees
7 Apr - 8 Apr
Rodeway Inn & Suites Houston near Medical Center

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,010 reviews)
"It was all okay."
United States
Tekle
The price is 2.026.767 ₫
2.378.747 ₫ total
includes taxes & fees
29 Mar - 30 Mar
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (196 reviews)
"This is an amazing place to stay."
United States
Darius
The price is 1.444.585 ₫
1.689.976 ₫ total
includes taxes & fees
17 Mar - 18 Mar
Wanderstay Houston Hostel

Paradise Palace Best Rooftop in HTX w Hot Tub

Paradise Palace Best Rooftop in HTX w Hot Tub
3.0 star property
South Central Houston
The price is 6.804.148 ₫
16.770.180 ₫ total
includes taxes & fees
2 Apr - 3 Apr
Paradise Palace Best Rooftop in HTX w Hot Tub

Posh Dtwn Midtown Home w Stunning Roof-topterrace

Posh Dtwn Midtown Home w Stunning Roof-topterrace
3.0 star property
South Central Houston
The price is 6.463.465 ₫
17.967.182 ₫ total
includes taxes & fees
18 Mar - 19 Mar
Posh Dtwn Midtown Home w Stunning Roof-topterrace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Top South Central Houston Hotel Reviews

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit Children's Museum of Houston and Houston Natural Science Museum as part of your South Central Houston travel plans.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1070 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Bagby Dog Park. Children's Museum of Houston and Houston Natural Science Museum are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.