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Check prices for these dates

In two weeks
16 Jan - 18 Jan
In two months
27 Feb - 1 Mar
In three months
27 Mar - 29 Mar
In four months
24 Apr - 26 Apr

Our top choices for La Mesa holiday rentals

Premium bedding, pillow-top beds, desk, laptop workspace
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (615)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is 2.882.479 ₫
4.104.082 ₫ total
includes taxes & fees
3 Jan - 4 Jan
Sentral Gaslamp Quarter
Beach nearby
Coronado Beach Resort

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (754)
"Room was clean, Staff pleasant. "
United States
Vicki
The price is 5.425.515 ₫
5.968.066 ₫ total
includes taxes & fees
20 Jan - 21 Jan
Coronado Beach Resort
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace
Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
8.0 out of 10, Very good, (154)
"Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. "
United States
Chris
Kasa Gaslamp Quarter San Diego
Lobby sitting area
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (266)
"Overall good place."
United States
Isaac
The price is 2.697.149 ₫
3.041.036 ₫ total
includes taxes & fees
4 Jan - 5 Jan
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Outdoor pool, a heated pool
Wave Crest Resort

Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (144)
"Great location "
United States
Erin
The price is 5.448.936 ₫
7.048.461 ₫ total
includes taxes & fees
7 Jan - 8 Jan
Wave Crest Resort
House (5 Bedrooms) | Interior
San Diego Home: AC, Hot Tub, Covered Patio & BBQ

San Diego Home: AC, Hot Tub, Covered Patio & BBQ

San Diego Home: AC, Hot Tub, Covered Patio & BBQ
3.0 star property
Spring Valley
The price is 5.625.632 ₫
14.439.998 ₫ total
includes taxes & fees
4 Jan - 5 Jan
San Diego Home: AC, Hot Tub, Covered Patio & BBQ
Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Family House, Private Bathroom | Terrace/patio
New Cozy Studio 2 Queen Beds, Kitchen Walk to Water

New Cozy Studio 2 Queen Beds, Kitchen Walk to Water

New Cozy Studio 2 Queen Beds, Kitchen Walk to Water
3.0 star property
Point Loma
8.0 out of 10, Very good, (1)
"The studio was beautiful, clean, and cozy. The only thing that I will say is that the pictures advertised show both the main home and the studio, so it is misleading as to what amenities are available in your own space. Other than that I enjoyed my stay and the owner was very prompt to respond to the few questions that I had."
United States
Fatimah
The price is 2.497.360 ₫
7.284.733 ₫ total
includes taxes & fees
13 Jan - 14 Jan
New Cozy Studio 2 Queen Beds, Kitchen Walk to Water
Apartment | 1 bedroom, Internet
NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna

NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna

NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna
2.0 star property
Downtown San Diego
The price is 4.292.636 ₫
10.212.531 ₫ total
includes taxes & fees
11 Jan - 12 Jan
NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna
Outdoor pool
Kasa Little Italy San Diego

Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (358)
"Clean room, Kitchen was fully equipped. Had a great stay!"
United States
Miranda
The price is 5.231.312 ₫
8.267.265 ₫ total
includes taxes & fees
4 Jan - 5 Jan
Kasa Little Italy San Diego
Cottage (2 Bedrooms) | Interior
Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
3.0 star property
Village of La Jolla
The price is 16.088.256 ₫
27.020.909 ₫ total
includes taxes & fees
4 Jan - 5 Jan
Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

10/10 Excellent
"Good "
Marco Emilio 1-night trip
Posted 13 hours ago
DoubleTree by Hilton Hotel San Diego - Mission Valley

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals in La Mesa close to Computer Museum of America, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many holiday rentals are there in La Mesa?

With 54 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit one of the family-friendly sights such as San Diego Zoo. While in the area, you can also visit popular places such as Mission Bay and Petco Park.

What are holiday rentals like in La Mesa?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering.