Search Holiday Rentals in La Mesa

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
27 Feb - 1 Mar
In two months
10 Apr - 12 Apr
In three months
8 May - 10 May
In four months
5 Jun - 7 Jun

Our top choices for La Mesa holiday rentals

Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (681 reviews)
"Great place to stay "
United States
KELLY
The price is 3.288.594 ₫
4.565.602 ₫ total
includes taxes & fees
15 Feb - 16 Feb
Sentral Gaslamp Quarter
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (296 reviews)
"The room was very small but very clean. Great place to stay for the short amount of time we needed it. "
United States
Debra
The price is 2.609.349 ₫
2.942.041 ₫ total
includes taxes & fees
11 Mar - 12 Mar
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Aerial view

Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (148 reviews)
"Clean and convenient location."
United States
Jeffrey
The price is 5.382.194 ₫
6.962.126 ₫ total
includes taxes & fees
17 Feb - 18 Feb
Wave Crest Resort
House (5 Bedrooms) | Interior

Fireplace, Hot Tub, Patio & Bbq: San Diego Home

Fireplace, Hot Tub, Patio & Bbq: San Diego Home
3.0 star property
Spring Valley
The price is 6.309.738 ₫
15.076.379 ₫ total
includes taxes & fees
17 Feb - 18 Feb
Fireplace, Hot Tub, Patio & Bbq: San Diego Home
Front of property – evening/night

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (767 reviews)
"Ideal location walkable to many restaurants and the beach. Great spot and lovely staff"
United States
Justine
The price is 6.128.301 ₫
6.741.131 ₫ total
includes taxes & fees
25 Feb - 26 Feb
Coronado Beach Resort
Outdoor pool

Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (372 reviews)
"Very clean, staff very pleasant, good location, comfortable "
Canada
Warren
The price is 5.842.350 ₫
8.935.262 ₫ total
includes taxes & fees
16 Feb - 17 Feb
Kasa Little Italy San Diego
Family House, Private Bathroom | Living area | Computer monitors

New Cozy Studio 2 Queen Beds, Kitchen Walk to Water

New Cozy Studio 2 Queen Beds, Kitchen Walk to Water
3.0 star property
Point Loma
8.0 out of 10, Very good, (1 review)
"The studio was beautiful, clean, and cozy. The only thing that I will say is that the pictures advertised show both the main home and the studio, so it is misleading as to what amenities are available in your own space. Other than that I enjoyed my stay and the owner was very prompt to respond to the few questions that I had."
United States
Fatimah
The price is 3.193.818 ₫
8.015.250 ₫ total
includes taxes & fees
16 Feb - 17 Feb
New Cozy Studio 2 Queen Beds, Kitchen Walk to Water
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (116 reviews)
"Very clean, quiet, walking distance to great food"
United States
Amanda
City24 Hotel Little Italy Mission Hills
Apartment | 1 bedroom, Internet

NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna

NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna
2.0 star property
Downtown San Diego
The price is 3.755.288 ₫
9.876.158 ₫ total
includes taxes & fees
17 Feb - 18 Feb
NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace

Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
8.0 out of 10, Very good, (160 reviews)
"Smelly building and elevator. Great location but super loud well into the night "
United States
alvaro
Kasa Gaslamp Quarter San Diego
Cottage (2 Bedrooms) | Interior

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
3.0 star property
Village of La Jolla
The price is 15.891.192 ₫
26.689.932 ₫ total
includes taxes & fees
18 Feb - 19 Feb
Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top La Mesa Hotel Reviews

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent
"The location was great, Hotel Circle is central to everything. The room was clean, the staff was excellent! We stayed in a kitchenette room and it was great to have. We'll stay there again! "
Teresa 3-night trip
Posted 1 day ago
Days Inn by Wyndham San Diego Hotel Circle

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals in La Mesa close to Computer Museum of America, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many holiday rentals are there in La Mesa?

With 62 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit one of the family-friendly sights such as San Diego Zoo. While in the area, you can also visit popular places such as Mission Bay and Mission Beach.

What are holiday rentals like in La Mesa?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering.