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Check prices for these dates

In two weeks
17 Apr - 19 Apr
In two months
29 May - 31 May
In three months
26 Jun - 28 Jun
In four months
24 Jul - 26 Jul

Our top choices for La Mesa holiday rentals

Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (813 reviews)
"Great location"
United States
Ethan
The price is 3.559.446 ₫
4.890.255 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Sentral Gaslamp Quarter
Exterior

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,049 reviews)
"The hotel was very clean and had very friendly staff. Location was amazing."
United States
Brenda
The price is 4.450.953 ₫
5.160.658 ₫ total
includes taxes & fees
23 Apr - 24 Apr
Marriott Vacation Club®, San Diego
House | 3 bedrooms, desk, Internet

Stunning View Mission Bay Luxury Home Private Pool

Stunning View Mission Bay Luxury Home Private Pool
2.0 star property
Bay Park
The price is 9.229.513 ₫
23.651.419 ₫ total
includes taxes & fees
12 Apr - 13 Apr
Stunning View Mission Bay Luxury Home Private Pool
Beach nearby

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (780 reviews)
"Excellent location, clean and cozy"
United States
Oksana
The price is 5.956.236 ₫
6.551.859 ₫ total
includes taxes & fees
28 Apr - 29 Apr
Coronado Beach Resort
Interior

Large Group Wellness Retreat w Spa & Gym

Large Group Wellness Retreat w Spa & Gym
3.0 star property
University City
The price is 11.193.225 ₫
25.762.525 ₫ total
includes taxes & fees
22 Apr - 23 Apr
Large Group Wellness Retreat w Spa & Gym
Cottage (2 Bedrooms) | Interior

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
3.0 star property
Village of La Jolla
The price is 16.118.244 ₫
27.071.276 ₫ total
includes taxes & fees
14 Apr - 15 Apr
Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
Aerial view

Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (151 reviews)
"Clean and convenient location."
United States
Jeffrey
The price is 5.239.077 ₫
6.813.049 ₫ total
includes taxes & fees
7 Apr - 8 Apr
Wave Crest Resort
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (330 reviews)
"It is a clean place to stay and budget friendly. Unfortunately the noise from the road can make it hard to sleep."
United States
Afia
The price is 3.077.478 ₫
3.469.856 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (135 reviews)
"Clean nice place to stay at"
United States
Luis
The price is 3.535.742 ₫
4.882.007 ₫ total
includes taxes & fees
6 Apr - 7 Apr
City24 Hotel Little Italy Mission Hills
Outdoor pool

Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (400 reviews)
"Excellent location Clean Just as showed in pictures"
United States
Carina Jose
The price is 5.241.063 ₫
8.282.676 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Kasa Little Italy San Diego
Lobby

Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (117 reviews)
"Perfect stay!"
United States
Kaylee
The price is 2.833.967 ₫
3.223.638 ₫ total
includes taxes & fees
6 Apr - 7 Apr
Little Italy Inn - Limited Service Apart Hotel
Apartment | 1 bedroom, desk, Internet

NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna

NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna
2.0 star property
Downtown San Diego
The price is 5.425.538 ₫
11.361.831 ₫ total
includes taxes & fees
5 Apr - 6 Apr
NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace

Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (176 reviews)
"Clean room, air conditioning worked and security is great "
United States
Elizabeth
The price is 2.726.086 ₫
3.106.238 ₫ total
includes taxes & fees
27 Apr - 28 Apr
Kasa Gaslamp Quarter San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

San Diego Mission Bay Resort

San Diego Mission Bay Resort

8/10 Good
"Great for a weekend getaway. Nice pool, great location, very family friendly. On the downside, the breakfast options were very okay and the days where you get breakfast credit are confusing and the staff won't bother clarifying beforehand."
Rashmi 3-night trip
Posted 2 hours ago
San Diego Mission Bay Resort

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals in La Mesa close to La Mesa Memorial Fine Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many holiday rentals are there in La Mesa?

With 64 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit one of the family-friendly sights such as San Diego Zoo. While in the area, you can also visit popular places such as Mission Bay and Petco Park.

What are holiday rentals like in La Mesa?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering.