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Check prices for these dates

In two weeks
22 May - 24 May
In two months
3 Jul - 5 Jul
In three months
31 Jul - 2 Aug
In four months
28 Aug - 30 Aug

Our top choices for La Mesa holiday rentals

Rooftop terrace

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (882 reviews)
"Great place with great amenities "
United States
Sean
The price is 3.780.868 ₫
5.146.613 ₫ total
includes taxes & fees
13 May - 14 May
Sentral Gaslamp Quarter
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (361 reviews)
"Great location love the pillows "
United States
Ronen Ben
The price is 3.114.709 ₫
3.511.834 ₫ total
includes taxes & fees
7 May - 8 May
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Lobby

Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (121 reviews)
"Perfect stay!"
United States
Kaylee
The price is 3.001.033 ₫
3.413.674 ₫ total
includes taxes & fees
10 May - 11 May
Little Italy Inn - Limited Service Apart Hotel
Aerial view

Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (153 reviews)
"Beautiful views clean property. "
United States
Irma
The price is 5.395.800 ₫
6.989.502 ₫ total
includes taxes & fees
11 May - 12 May
Wave Crest Resort
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace

Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (182 reviews)
"Fantastic stay at Kasa! The room was spotless and very modern. You really can’t beat the location—it’s smack in the middle of the Gaslamp Quarter, so everything is walkable. It’s also surprisingly affordable for such a prime area. Highly recommend if you want to be where the action is!"
United States
Aurelio
The price is 2.581.992 ₫
2.942.052 ₫ total
includes taxes & fees
25 May - 26 May
Kasa Gaslamp Quarter San Diego
Exterior

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,075 reviews)
"Wonderful place. Clean and friendly "
United States
Iuliia
The price is 4.228.308 ₫
4.902.511 ₫ total
includes taxes & fees
21 May - 22 May
Marriott Vacation Club®, San Diego
House (4 Bedrooms) | Interior

Explore Ramona's Vineyards: Tranquil Home w/ Yard

Explore Ramona's Vineyards: Tranquil Home w/ Yard
3.0 star property
Ramona
The price is 8.369.760 ₫
18.457.163 ₫ total
includes taxes & fees
26 May - 27 May
Explore Ramona's Vineyards: Tranquil Home w/ Yard
Beach nearby

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (790 reviews)
"Great place"
United States
scott
The price is 6.295.499 ₫
6.925.049 ₫ total
includes taxes & fees
25 May - 26 May
Coronado Beach Resort
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (145 reviews)
"Love the design and decor and the hotel is close to the airport ease of parking. With that being said, it can be a little loud outside but it was still a great stay overall."
United States
Rose
The price is 4.935.000 ₫
6.459.092 ₫ total
includes taxes & fees
11 May - 12 May
City24 Hotel Little Italy Mission Hills
Outdoor pool

Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (420 reviews)
"Great place to stay when visiting San Diego. The apartment was exceptionally clean. Amenities were awesome, including the pool, workout room and massage chair. Location was perfect for visiting all the tourist attractions. Would definitely stay here again. "
United States
Tiffany
The price is 5.241.859 ₫
8.283.934 ₫ total
includes taxes & fees
11 May - 12 May
Kasa Little Italy San Diego
Cottage (2 Bedrooms) | Interior

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!

Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
3.0 star property
Village of La Jolla
The price is 16.107.840 ₫
27.053.802 ₫ total
includes taxes & fees
11 May - 12 May
Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

California Suites Hotel

California Suites Hotel

8/10 Good
"Helpful staff"
Klaw 6-night trip
Posted 6 hours ago
California Suites Hotel

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals in La Mesa close to La Mesa Memorial Fine Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many holiday rentals are there in La Mesa?

With 68 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

Explore the area and cultural attractions such as Computer Museum of America, or visit one of the family-friendly sights such as San Diego Zoo. While in the area, you can also visit popular places such as Mission Bay and Petco Park.

What are holiday rentals like in La Mesa?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering.