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Check prices for these dates

In two weeks
23 Oct - 25 Oct
In two months
4 Dec - 6 Dec
In three months
1 Jan - 3 Jan
In four months
29 Jan - 31 Jan

Our top choices for La Mesa holiday rentals

A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

1. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,239 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
The price is 4.834.884 ₫
5.605.807 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Marriott Vacation Club®, San Diego
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

2. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (221 reviews)
"Friendly staff!"
United States
Donavin
The price is 3.012.705 ₫
4.280.692 ₫ total
includes taxes & fees
26 Oct - 27 Oct
City24 Hotel Little Italy Mission Hills
An outdoor lounge area with sun loungers and umbrellas, a pool, and a building with a dome and a staircase.

3. Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.2 out of 10, Wonderful, (830 reviews)
"Amazing location, amenities, staff"
United States
Javier
The price is 5.296.928 ₫
5.826.621 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Coronado Beach Resort
A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

4. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (481 reviews)
"We had a great stay! The room had a charming Parisian feel—compact and studio-style, but completely modern and spotlessly clean."
United States
Josh
The price is 2.430.395 ₫
2.740.271 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
A rooftop pool with lounge chairs and a city skyline in the background.

5. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
Downtown San Diego
9.6 out of 10, Exceptional, (542 reviews)
"Perfect location, great pool, beds were comfy. No complaints"
United States
Jeremy
The price is 5.731.677 ₫
8.811.612 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Kasa Little Italy San Diego
A modern lobby with a green sofa, a wooden accent wall, and a large plant.

6. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.4 out of 10, Very good, (336 reviews)
"great stay"
United States
alex
The price is 2.541.381 ₫
2.941.649 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Little Italy Inn - Limited Service Apart Hotel
A coastal residential area with houses, a well-maintained lawn, and a view of the ocean.

7. Wave Crest Resort

Wave Crest Resort
3.0 star property
Del Mar
9.2 out of 10, Wonderful, (159 reviews)
"wow, this is the best place ever. I had an amazing vacation. The staff was most hospitable. easy parking. I could hear the ocean at night while I slept. makes for a heavenly sleep only a 5-minute walk to the beach, but you could see the ocean from the room."
United States
Erik
The price is 5.299.891 ₫
6.870.073 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Wave Crest Resort
A modern living room with a sofa, a TV, a floor lamp, and a large window offering a city view.

8. Rooftop w/ Views: Modern Little Italy Townhome

Rooftop w/ Views: Modern Little Italy Townhome
3.5 star property
Downtown San Diego
10.0 out of 10, Exceptional, (1 review)
The price is 7.356.302 ₫
17.048.685 ₫ total
includes taxes & fees
14 Oct - 15 Oct
Rooftop w/ Views: Modern Little Italy Townhome
A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

9. Kasa Gaslamp Quarter San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
Downtown San Diego
7.8 out of 10, Good, (233 reviews)
"Wonderful place!"
Canada
Eric
The price is 3.158.271 ₫
3.598.692 ₫ total
includes taxes & fees
14 Oct - 15 Oct
Kasa Gaslamp Quarter San Diego
A living room with a white sofa, two blue armchairs, a wooden coffee table, and a painting on the wall.

10. < 2 Mi to Pacific Beach! Sunny San Diego Escape

< 2 Mi to Pacific Beach! Sunny San Diego Escape
3.0 star property
Pacific Beach
7.4 out of 10, Good, (3 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
The price is 9.123.894 ₫
20.146.650 ₫ total
includes taxes & fees
8 Oct - 9 Oct
< 2 Mi to Pacific Beach! Sunny San Diego Escape
A modern building with a unique architectural design, featuring a balcony and a wooden deck area.

11. 2BR Condo Steps to the Beach & Blvd-dog-friendly

2BR Condo Steps to the Beach & Blvd-dog-friendly
3.0 star property
Mission Beach
The price is 7.876.182 ₫
17.843.581 ₫ total
includes taxes & fees
8 Oct - 9 Oct
2BR Condo Steps to the Beach & Blvd-dog-friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Bay Club Hotel & Marina

Bay Club Hotel & Marina

10/10 Excellent
"Great location and friendly staff."
Thuan 1-night trip
Posted 4 hours ago
Bay Club Hotel & Marina

Frequently asked questions

Are there holiday rentals in La Mesa?

Yes, there are holiday rentals in La Mesa close to La Mesa Memorial Fine Arts Center, or you can select a more secluded option if you're looking for a relaxing stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

How many holiday rentals are there in La Mesa?

With 65 Expedia holiday rentals, you're guaranteed to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

While exploring the area, visit family-friendly sights like San Diego Zoo, or get outside and enjoy nature at Mission Bay. While in the area, you can also visit popular places such as Petco Park and Port of San Diego.

What are holiday rentals like in La Mesa?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in La Mesa. Holiday rentals feature amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great choice for a small group gathering.