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Check prices for these dates

Tonight
4 Feb - 5 Feb
Tomorrow
5 Feb - 6 Feb
This weekend
6 Feb - 8 Feb
Next weekend
13 Feb - 15 Feb

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Our top choices for Main Street Hyannis hotels

Interior entrance

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,002 reviews)
"Very nice stay"
United States
Robert
The price is 3.486.868 ₫
4.734.637 ₫ total
includes taxes & fees
9 Feb - 10 Feb
Anchor In Distinctive Waterfront Lodging
Dining

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45 reviews)
"Adrian was an awesome host. Comfortable bed, safe area to walk, beautiful surroundings."
United States
Jori
The price is 5.980.460 ₫
6.844.766 ₫ total
includes taxes & fees
11 Feb - 12 Feb
Sea Street Inn
Indoor pool, seasonal outdoor pool

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
3.0 star property
1.9 km from Main Street Hyannis
9.2 out of 10, Wonderful, (104 reviews)
"Clean, nice staff, good amenities, central location"
United States
Malbis
The price is 3.060.435 ₫
3.625.085 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Uncommoner Hotel by Reverie Boutique Collection
Indoor pool, seasonal outdoor pool

The Cove at Yarmouth by Westgate Resorts

The Cove at Yarmouth by Westgate Resorts
3.0 star property
2.1 km from Main Street Hyannis
9.2 out of 10, Wonderful, (251 reviews)
"Was unaware that pool facilities were closed for 2 weeks of maintenance which was primary purpose of stay"
United States
Edward
The price is 3.349.968 ₫
3.834.038 ₫ total
includes taxes & fees
5 Feb - 6 Feb
The Cove at Yarmouth by Westgate Resorts
Indoor pool

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (490 reviews)
"Parking was free and easy, room was very clean and housekeeping service was top notch. "
United States
Maureen
The price is 3.540.432 ₫
4.052.025 ₫ total
includes taxes & fees
22 Feb - 23 Feb
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,000 reviews)
"They were excellent. Felt extremely comfortable. Their breakfast was amazing, staff were so friendly!"
United States
Linda
The price is 2.963.708 ₫
3.391.964 ₫ total
includes taxes & fees
11 Feb - 12 Feb
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool

Courtyard Resort

Courtyard Resort
2.0 star property
0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (55 reviews)
"It was ok. Best part was it was near everything. "
United States
Kimberly
The price is 2.834.218 ₫
3.243.762 ₫ total
includes taxes & fees
9 Feb - 10 Feb
Courtyard Resort
Lobby

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
2.5 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (676 reviews)
"Excellent staff-clean rooms-great location"
United States
Patrice
The price is 3.302.254 ₫
3.779.429 ₫ total
includes taxes & fees
9 Feb - 10 Feb
Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,544 reviews)
"The place was clean, staff very nice and a good breakfast! Nice pool and beach area."
United States
LisaAnn
The price is 2.470.190 ₫
3.124.856 ₫ total
includes taxes & fees
8 Feb - 9 Feb
Bayside Resort Hotel
Exterior

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (889 reviews)
"It was a decent stay I can’t complain "
United States
Rony
The price is 3.325.136 ₫
3.805.618 ₫ total
includes taxes & fees
7 Feb - 8 Feb
Doubletree by Hilton Cape Cod - Hyannis
Free daily continental breakfast

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1,000 reviews)
"Nice hotel had a perfect stay"
United States
David
The price is 2.550.796 ₫
2.919.386 ₫ total
includes taxes & fees
12 Feb - 13 Feb
Comfort Inn Hyannis - Cape Cod
Exterior

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,002 reviews)
"Lovely stay! One of the best hotels to stay in Hyannis. "
United States
Mary
The price is 3.248.950 ₫
4.768.384 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Hyannis Harbor Hotel
Exterior

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,020 reviews)
"Room was nice and spacious, very clean. Upstairs people was a little loud but other than that the stay was good. Would definitely stay again. "
United States
Celestina
The price is 1.939.229 ₫
2.219.271 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Cape Sands Inn
Exterior

Holiday Inn Hyannis by IHG

Holiday Inn Hyannis by IHG
3.0 star property
2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (988 reviews)
"Great place to stay "
United States
Lilian
The price is 2.964.228 ₫
3.392.559 ₫ total
includes taxes & fees
9 Feb - 10 Feb
Holiday Inn Hyannis by IHG
Exterior

Sea Breeze Inn

Sea Breeze Inn
2.5 star property
1.8 km from Main Street Hyannis
7.8 out of 10, Good, (193 reviews)
"Nice place to stay "
United States
Kevin
The price is 2.314.178 ₫
2.648.564 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Sea Breeze Inn
Lobby

Hyannis Plaza Hotel

Hyannis Plaza Hotel
2.5 star property
0.9 km from Main Street Hyannis
7.0 out of 10, Good, (1,001 reviews)
"The best staff abd it was clean and beautiful "
United States
Heather
The price is 1.892.686 ₫
2.426.199 ₫ total
includes taxes & fees
6 Mar - 7 Mar
Hyannis Plaza Hotel
Family House, Private Bathroom, Pool View | Lounge

Sal's Place

Sal's Place
2.0 star property
2.5 km from Main Street Hyannis
The price is 10.400.800 ₫
15.023.956 ₫ total
includes taxes & fees
5 Feb - 6 Feb
Sal's Place
Front of property

The Village Inn Cape Cod

The Village Inn Cape Cod
3.5 star property
6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (224 reviews)
"It was so charming, would definitely stay there again! "
United States
Kyle
The price is 5.330.410 ₫
6.100.849 ₫ total
includes taxes & fees
5 Feb - 6 Feb
The Village Inn Cape Cod
Outdoor pool, pool umbrellas, pool loungers

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod
4.0 star property
3.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (441 reviews)
"Excellent,very clean "
United States
Quezia
The price is 4.011.312 ₫
6.079.041 ₫ total
includes taxes & fees
10 Feb - 11 Feb
Margaritaville Resort Cape Cod
Property grounds

The Escape Inn

The Escape Inn
2.5 star property
7.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (669 reviews)
"Great place"
United States
Karim
The price is 2.088.481 ₫
2.390.364 ₫ total
includes taxes & fees
5 Feb - 6 Feb
The Escape Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Hyannis Hotel Reviews

Courtyard Resort

Courtyard Resort

10/10 Excellent
"Room what nice very easy check in.. The only thing is the toilet flooded our room but they moved us to another unit no problem! I always enjoy my stay at courtyard resort"
Michael 1-night trip
Posted 2 months ago
Courtyard Resort

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum showcases bronze statue and historic architecture in Hyannis Massachusetts

John F. Kennedy Hyannis Museum

4.4/5 (259 reviews)
You can spend an afternoon studying the exhibits at John F. Kennedy Hyannis Museum during your travels in Hyannis. Wander through the beautiful beaches and waterfront in this family-friendly area.
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Cape Cod Maritime Museum which includes a bay or harbor and signage

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the beautiful beaches in this family-friendly area or visit its seafood restaurants.
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Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 188 hotels and other accommodation options you'll find within a mile.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 188 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Whydah Pirate Museum and Cape Cod Maritime Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. You can enjoy live performances at Cape Cod Melody Tent and Barnstable Performing Arts Center.