Where to stay in Mission Bay
Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Fisherman's Wharf
1 out of top 10 points of interest in this area
Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.
Union Square
Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.
Downtown San Francisco
3 out of top 10 points of interest in this area
Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.
South of Market
Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.
Nob Hill
Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.
Top hotels in Mission Bay
LUMA Hotel San Francisco
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
6.141.960 ₫
7.228.956 ₫ total
16 Aug - 17 Aug
includes taxes & fees
9.6/10 Exceptional! (2,605 reviews)
"Great spot!"
Reviewed on 12 Aug 2026
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
3.972.672 ₫
4.675.730 ₫ total
31 Aug - 1 Sept
includes taxes & fees
9/10 Wonderful! (6,137 reviews)
"Comfortable bed, friendly staff, very convenient location."
Reviewed on 12 Aug 2026
Hotel Riu Plaza Fisherman's Wharf
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
3.684.940 ₫
5.413.792 ₫ total
23 Aug - 24 Aug
includes taxes & fees
9/10 Wonderful! (7,597 reviews)
"Beautiful place and super friendly staff!"
Reviewed on 12 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Mission Bay holiday package cost?
Custom make your Mission Bay holiday package from as low as . Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay holiday package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1null000null000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay holiday?
Smart travellers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organising an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia holiday package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay holiday package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay holiday package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
Stay near popular Mission Bay attractions
Chase Center
8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
Mission Bay Conference Center at UCSF
Learn about the events happening in Mission Bay Conference Center at UCSF during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
PIER 48 - Lot #39
After visiting PIER 48 - Lot #39, make a plan to see the other sights and activities in San Francisco. Amble around this vibrant area's Chinatown or seek out the local tours.
Lefty O'Doul Bridge
You can find out about the history of San Francisco with a stop at Lefty O'Doul Bridge. Take in the acclaimed theatre scene and beautiful sunsets in this vibrant area.
Lucky Strike San Francisco
You can take time to visit Lucky Strike San Francisco during your travels to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.