Mission Bay Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Union Square

Union Square

4/5(289 area reviews)

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Find hotels in Union Square

Top hotels in Mission Bay

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is 6.028.196 ₫ per night from 29 May to 30 May
6.028.196 ₫
7.094.844 ₫ total
29 May - 30 May
includes taxes & fees
9.6/10 Exceptional! (2,497 reviews)
Lose to Giants and Warriors for games! Even for UCSF visits. Hotel was clean and had all the amenities!!! Staff were amazing!

Reviewed on 11 May 2026

LUMA Hotel San Francisco
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is 3.922.539 ₫ per night from 25 May to 26 May
3.922.539 ₫
5.700.989 ₫ total
25 May - 26 May
includes taxes & fees
9/10 Wonderful! (7,507 reviews)
good location, great price, good value overall.

Reviewed on 12 May 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is 3.608.494 ₫ per night from 7 Jun to 8 Jun
3.608.494 ₫
4.247.017 ₫ total
7 Jun - 8 Jun
includes taxes & fees
8.8/10 Excellent! (2,745 reviews)
Excellent location, lobby impersonal. Parking very expensive. Nice staff and rooms.

Reviewed on 11 May 2026

Hilton San Francisco Financial District
See all 4,528 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Bay holiday package cost?
Custom make your Mission Bay holiday package from as low as . Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay holiday package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1null000null000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay holiday?
Smart travellers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organising an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia holiday package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay holiday package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay holiday package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Popular places to visit

Chase Center San Francisco Skyline Aerial Photography

Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

Chase Center
Golden Gate Park

Golden Gate Park

Golden Gate Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Stroll along the seaside or experience the acclaimed theatre scene in this vibrant area.

Golden Gate Park
Pier 39

Pier 39

You can find the perfect gifts to bring home when you visit Pier 39, a popular shopping spot in San Francisco. Discover the beautiful sunsets and notable monuments in this vibrant area.

Pier 39