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Our top choices for Missouri Institute of Natural Science hotels

Free daily buffet breakfast
Holiday Inn Express and Suites Springfield Medical District by IHG

Holiday Inn Express and Suites Springfield Medical District by IHG

Holiday Inn Express and Suites Springfield Medical District by IHG
3.0 star property
4.6 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (954)
"Very clean, courteous staff, good breakfast!"
United States
Jason
The price is 2.922.741 ₫
3.317.603 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express and Suites Springfield Medical District by IHG
Terrace/patio
Homewood Suites by Hilton Springfield Medical District

Homewood Suites by Hilton Springfield Medical District

Homewood Suites by Hilton Springfield Medical District
3.0 star property
5.5 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (459)
"Beautiful room and very friendly staff"
United States
Amanda
The price is 2.893.250 ₫
3.284.128 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Homewood Suites by Hilton Springfield Medical District
Lobby sitting area
Bass Pro Shops Angler's Lodge

Bass Pro Shops Angler's Lodge

Bass Pro Shops Angler's Lodge
2.5 star property
Fassnight, 8.9 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (1955)
"Staff was amazing and nice. Room was comfortable and bed was very comfortable."
United States
leon p.
Bass Pro Shops Angler's Lodge
In-room safe, desk, iron/ironing board, free WiFi
Candlewood Suites Springfield-Medical District

Candlewood Suites Springfield-Medical District

Candlewood Suites Springfield-Medical District
2.5 star property
5.5 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (410)
"Clean room. Close to everything. Will book again. "
United States
Brian
The price is 2.763.180 ₫
3.136.486 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
Candlewood Suites Springfield-Medical District
Property amenity
Residence Inn by Marriott Springfield

Residence Inn by Marriott Springfield

Residence Inn by Marriott Springfield
3.0 star property
6.1 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (958)
"Amazing breakfast"
Spain
ROSA
The price is 3.109.235 ₫
3.529.293 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Residence Inn by Marriott Springfield
Room, 2 Queen Beds, Non Smoking | Premium bedding, down duvets, pillow-top beds, in-room safe
La Quinta Inn & Suites by Wyndham Springfield South

La Quinta Inn & Suites by Wyndham Springfield South

La Quinta Inn & Suites by Wyndham Springfield South
3.0 star property
Seminole Holland, 7.6 km from Missouri Institute of Natural Science
8.8 out of 10, Excellent, (1007)
"Enjoyed our stay"
United States
Frank
The price is 2.210.544 ₫
2.557.579 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
La Quinta Inn & Suites by Wyndham Springfield South
Lobby
Sleep Inn Springfield South I60 near Medical District

Sleep Inn Springfield South I60 near Medical District

Sleep Inn Springfield South I60 near Medical District
3.0 star property
4.4 km from Missouri Institute of Natural Science
8.2 out of 10, Very good, (806)
"Staff were excellent to deal with, parking was good, breakfast was very good and was conveniently located too gas stations and restaurants. "
United States
Floyd
The price is 2.342.669 ₫
2.659.164 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Sleep Inn Springfield South I60 near Medical District
Lobby lounge
Hampton Inn Springfield-South

Hampton Inn Springfield-South

Hampton Inn Springfield-South
2.5 star property
Galloway Village, 8.1 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (613)
"Breakfast and bed great."
United States
Gregory
The price is 2.460.546 ₫
2.792.966 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Springfield-South
Lobby
Quality Inn & Suites

Quality Inn & Suites

Quality Inn & Suites
2.5 star property
4.2 km from Missouri Institute of Natural Science
8.0 out of 10, Very good, (709)
"It was wonderful "
United States
Tammy
The price is 1.804.727 ₫
2.048.545 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn & Suites
Exterior
The Bradford Hotel, an Ascend Collection Hotel

The Bradford Hotel, an Ascend Collection Hotel

The Bradford Hotel, an Ascend Collection Hotel
2.5 star property
Bradford Park, 6.2 km from Missouri Institute of Natural Science
8.6 out of 10, Excellent, (234)
"The room was clean and scent free. I would stay here again."
United States
Jordana
The price is 2.063.034 ₫
2.341.750 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
The Bradford Hotel, an Ascend Collection Hotel
Front of property
Hilton Garden Inn Springfield, MO

Hilton Garden Inn Springfield, MO

Hilton Garden Inn Springfield, MO
3.0 star property
7.6 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (819)
"Comfortable beds, nice staff"
United States
Jennifer
The price is 2.893.250 ₫
3.314.507 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Hilton Garden Inn Springfield, MO
Free daily full breakfast
Comfort Inn South - Springfield

Comfort Inn South - Springfield

Comfort Inn South - Springfield
2.5 star property
Galloway Village, 7.8 km from Missouri Institute of Natural Science
8.6 out of 10, Excellent, (1002)
"Nice room, friendly staff "
United States
James
The price is 2.430.351 ₫
2.758.690 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Comfort Inn South - Springfield
Lobby
MainStay Suites Springfield South - Battlefield Rd

MainStay Suites Springfield South - Battlefield Rd

MainStay Suites Springfield South - Battlefield Rd
2.0 star property
Bradford Park, 7.9 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (82)
"Nice Hotel"
United States
Earl
The price is 2.214.491 ₫
2.513.670 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
MainStay Suites Springfield South - Battlefield Rd
Lobby
Element Springfield South

Element Springfield South

Element Springfield South
3.0 star property
Meador Park, 7.4 km from Missouri Institute of Natural Science
9.0 out of 10, Wonderful, (99)
"Very solid hotel, clean and very spacious "
United States
Landon
The price is 3.000.024 ₫
3.405.326 ₫ total
includes taxes & fees
23 Jan - 24 Jan 2026
Element Springfield South
Property entrance
Greenstay Inn & Suites CourtView

Greenstay Inn & Suites CourtView

Greenstay Inn & Suites CourtView
2.5 star property
Galloway Village, 10.7 km from Missouri Institute of Natural Science
8.8 out of 10, Excellent, (1138)
"Very clean and quiet. Friendly front desk staff and comfy beds. "
United States
Brandi
The price is 1.897.965 ₫
2.154.381 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Greenstay Inn & Suites CourtView
Exterior
Vīb Best Western Springfield

Vīb Best Western Springfield

Vīb Best Western Springfield
3.0 star property
Oak Grove, 10.4 km from Missouri Institute of Natural Science
8.8 out of 10, Excellent, (1000)
"Nice place to stay "
United States
Jane
The price is 2.382.166 ₫
2.703.997 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Vīb Best Western Springfield
Front of property
TownePlace Suites Springfield

TownePlace Suites Springfield

TownePlace Suites Springfield
3.0 star property
Seminole Holland, 9.2 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (605)
"Great place to stay"
United States
Amy
The price is 2.936.866 ₫
3.333.636 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
TownePlace Suites Springfield
Lobby
Hampton Inn Springfield-Southeast

Hampton Inn Springfield-Southeast

Hampton Inn Springfield-Southeast
2.5 star property
Galloway Village, 10.6 km from Missouri Institute of Natural Science
9.4 out of 10, Exceptional, (800)
"Very nice hotel. Clean and friendly staff. Very pet friendly."
United States
Maria
The price is 2.697.390 ₫
3.061.808 ₫ total
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn Springfield-Southeast
Lobby
Tru by Hilton Springfield Downtown

Tru by Hilton Springfield Downtown

Tru by Hilton Springfield Downtown
2.5 star property
Downtown Springfield, 11.6 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (897)
"Comfy bed .. good breakfast "
United States
Page
The price is 2.783.706 ₫
3.174.539 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Tru by Hilton Springfield Downtown
Room, 1 King Bed, Balcony | Premium bedding, in-room safe, blackout curtains, iron/ironing board
Hotel Vandivort

Hotel Vandivort

Hotel Vandivort
4.0 star property
Downtown Springfield, 11.7 km from Missouri Institute of Natural Science
9.2 out of 10, Wonderful, (1000)
"Great place! Close to lots of stuff to do."
United States
Charles
The price is 4.230.075 ₫
4.823.839 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hotel Vandivort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Missouri Institute of Natural Science Hotel Reviews

Hotels near other Missouri Institute of Natural Science attractions

Trail of Tears Park

After visiting Trail of Tears Park, make a plan to see the other sights and activities in Battlefield.
See properties

Trail of Tears National Historic Trail

You can take time to visit Trail of Tears National Historic Trail during your travels to Springfield. Experience the entertainment choices or attend a sporting event in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Missouri Institute of Natural Science?
Missouri Institute of Natural Science is located in Springfield. This family-friendly area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 5 hotels and other accommodation options you'll find within a mile.
How many hotels are there close to Missouri Institute of Natural Science?
Expedia has 5 hotels and other accommodation options within a mile from Missouri Institute of Natural Science.
If I need to cancel the hotel reservation for my stay near Missouri Institute of Natural Science, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals available near Missouri Institute of Natural Science.
What can I see and do near Missouri Institute of Natural Science?
You might spend a leisurely day outdoors at Mizumoto Japanese Stroll Garden and Nathanael Greene/Close Memorial Park. You might plan a visit to Trail of Tears National Historic Trail or Rivercut Golf Course while you're in the area. If you want to see more of the surrounding area, you can plan a visit to Ray House and Nixa City Hall.