Search Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very good, (1,727 reviews)
"The location is great if you are crossing late from Tijuana to San Diego and you need to rest, the room is super clean, and very comfortable. "
Rafael Moreno
The price is 3.294.500 ₫
3.747.560 ₫ total
includes taxes & fees
31 May - 1 Jun
Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.0 out of 10, Good, (1,007 reviews)
"The only hotel in otay mesa and overall the service was good"
MARIA
The price is 2.562.594 ₫
2.914.951 ₫ total
includes taxes & fees
31 May - 1 Jun
Best Western Yacht Harbor Hotel
Best Western Yacht Harbor Hotel29.9 km from Otay Mesa
8.4 out of 10, Very good, (1,859 reviews)
"Very good breakfast offered; room was clean and comfortable; free parking; great area, close to downtown, Mission Beach and Liberty market. "
Jeffrey
The price is 2.818.487 ₫
3.234.148 ₫ total
includes taxes & fees
31 May - 1 Jun
Hampton Inn & Suites Imperial Beach San Diego
Hampton Inn & Suites Imperial Beach San Diego13.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,003 reviews)
"Room was great, very clean. Staff was so friendly and helpful. Other visitors were great conversation over breakfast. Tons of places to eat walking distance and super close to the beach. For the price it was incredible. Will be returning soon. "
Isabel
The price is 3.562.013 ₫
4.067.640 ₫ total
includes taxes & fees
10 May - 11 May
Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very good, (3,520 reviews)
"Great stay and family friendly "
Gregory
The price is 4.451.629 ₫
6.449.252 ₫ total
includes taxes & fees
25 May - 26 May
Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,891 reviews)
"Amazing rooms and casino "
Bryan
The price is 2.597.223 ₫
3.173.037 ₫ total
includes taxes & fees
6 May - 7 May
Best Western San Diego Pacific Beach/Mission Bay
Best Western San Diego Pacific Beach/Mission BayBay Park, 33.6 km from Otay Mesa
8.2 out of 10, Very good, (377 reviews)
"Great room. Staff was friendly. Easy access to trolley and free parking made getting around super easy. "
Jason
The price is 2.296.135 ₫
2.639.292 ₫ total
includes taxes & fees
10 May - 11 May
Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,658 reviews)
"The staff is always polite. Always friendly and welcoming. Way different place to visit then it was years ago. It's clean and pleasant. "
wes
The price is 2.059.603 ₫
2.269.541 ₫ total
includes taxes & fees
18 May - 19 May
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,061 reviews)
"It was clean and convenient to the airport."
Joey L
The price is 3.716.196 ₫
4.271.582 ₫ total
includes taxes & fees
10 May - 11 May
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (641 reviews)
"Clean and spacious room. Amazing outdoor pool/jacuzzi with outdoor seating and a nice fire pit. The bartender Mico is THEE BEST! "
Shatera
The price is 5.192.132 ₫
5.721.471 ₫ total
includes taxes & fees
17 May - 18 May
Ocean Villa Inn
Ocean Villa InnOcean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very good, (1,268 reviews)
"Basic beach motel. Served its purpose. Its old and dingy but it was quiet and safe. Manager was very nice. "
Karin
The price is 3.180.906 ₫
3.586.472 ₫ total
includes taxes & fees
6 May - 7 May
Lafayette Hotel & Club
Lafayette Hotel & Club26.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,631 reviews)
"I loved this hotel. It was absolutely my type the staff was lovely and I would go back."
Evelyn
The price is 6.558.909 ₫
7.539.138 ₫ total
includes taxes & fees
18 May - 19 May
Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay6.9 km from Otay Mesa
8.0 out of 10, Very good, (1,638 reviews)
"Clean room, friendly and nice staff, easy parking and safe "
Erik
The price is 2.108.480 ₫
2.402.349 ₫ total
includes taxes & fees
6 May - 7 May
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,809 reviews)
"The room was clean, staff was really friendly and helpful, there is plenty of parking spots.
I would definitely stay again in this hotel "
Jessica
The price is 4.190.604 ₫
4.617.835 ₫ total
includes taxes & fees
10 May - 11 May
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld31.3 km from Otay Mesa
7.4 out of 10, Good, (4,224 reviews)
"Room was clean hotel was close to beach & restaurant "
Andrea
The price is 2.871.169 ₫
3.300.265 ₫ total
includes taxes & fees
6 May - 7 May
Days Inn by Wyndham San Diego-East/El Cajon
Days Inn by Wyndham San Diego-East/El Cajon27.3 km from Otay Mesa
7.8 out of 10, Good, (1,008 reviews)
"My room was perfect in every way. The complimentary breakfast was excellent, plenty of variety and quantity with nice seating.
Day’s Inn has a great location for traveling on foot, bus or trolley to many locations.
I will stay here again on my next trip. "
Marla
The price is 2.328.544 ₫
2.565.876 ₫ total
includes taxes & fees
7 May - 8 May
Bay Club Hotel & Marina
Bay Club Hotel & Marina29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (3,568 reviews)
"Room was very clean, staff was friendly and location was amazing!!"
Erica
The price is 4.010.065 ₫
4.609.369 ₫ total
includes taxes & fees
6 May - 7 May
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 33.1 km from Otay Mesa
8.4 out of 10, Very good, (1,438 reviews)
"Staff were very friendly and accommodating
The resort was beautiful and location was amazing"
Valerie
The price is 5.768.679 ₫
8.023.732 ₫ total
includes taxes & fees
10 May - 11 May
Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,128 reviews)
"Location was fairly convenient to most attractions. The staff was awesome. Breakfast was good. The fact that we didn't have to pay for parking was one of the reasons we chose this hotel compared to others in the San Diego area."
Melissa
The price is 3.405.195 ₫
3.745.715 ₫ total
includes taxes & fees
25 May - 26 May
Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,268 reviews)
"Clean room, nice staff, a simple breakfast, and free parking on site."
Nicole
The price is 3.222.031 ₫
3.665.060 ₫ total
includes taxes & fees
10 May - 11 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Ocean Beach Farmers Market.
