All Hotels by Motel 6 in Roxana - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Roxana Motel 6

Motel 6 Hazelwood, MO

Hazelwood

Jasmine

2.000.752 ₫ total

includes taxes & fees

5 Jul - 6 Jul

Motel 6 Caseyville, IL - Caseyville Il

Caseyville

Daniel

1.655.951 ₫ total

includes taxes & fees

5 Jul - 6 Jul

Motel 6 Troy, IL

Troy

Baturalp

2.042.829 ₫ total

includes taxes & fees

30 Jun - 1 Jul

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Roxana Hotel Reviews

21C Museum Hotel St Louis

10/10 Excellent

"Excellent Would highly recommend to others. Also recommend staying at the Hilton at union station."

Moonrise Hotel

10/10 Excellent

"Wonderful stay. Sebastian greeted us at the front desk. He was helpful, knowledgeable, kind and friendly. We ate at the downstairs restaurant (upstairs rooftop restaurant closed due to AC issues -- extre heat wave). The staff was so wonderful. All staff friendly and helpful. Food was good, service excellent. The room was clean, modern updates and stylish. The area around the hotel was a fun area -- pedestrian friendly --lots of restaurants and some entertainment. In site parking for no extra fee was great. We had a great experience."

Forest Park Hotel by MDR

8/10 Good

"We stayed at this hotel a couple of years ago, and it seems to have gone downhill a bit since then. The room was clean but not well maintained with certain items that should really have been replaced like the desk chair. Also one of the two elevators was out. The check in was a bit of a mess with the front desk not assisting people in the order that they had come to the desk (even though there were only three of us). It was also impossible to reach the hotel with a question before my stay. No one answered at any numbers I found online. The email address I found online bounced back, and they never answered any of the messages sent through Expedia. When I went to check out no one was at the desk. I rang the bell but no one came, and I could hear their phone ringing off the hook. There were several keys lying on the desk next to a sign that said “welcome.” I assumed (hoped) this was a key drop off (albeit an unsecured one), so I added my key to the pile and left. The hotel is very close to the Muny, and it is quiet and in a safe neighborhood, but right now that is the main thing it has going for it. I hope they make improvements and that it does not continue to go downhill. Making it easier to ask pre-check in questions would be a good start."

Explore a world of travel with Expedia

More ways to book

Book Motel 6 in Roxana on Expedia.com

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Roxana Motel 6

Motel 6 Hazelwood, MO

Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Troy, IL

Top Roxana Hotel Reviews

21C Museum Hotel St Louis

Moonrise Hotel

Clayton Plaza Hotel & Extended Stay

St. Louis Union Station Hotel, Curio Collection by Hilton

Pear Tree Inn St. Louis Airport

Drury Plaza Hotel St. Louis at the Arch

Home2 Suites by Hilton St. Louis Downtown

Pear Tree Inn St. Louis Near Union Station

Forest Park Hotel by MDR

Explore a world of travel with Expedia

Search Hotels by Motel 6 in Roxana from 1.655.951 ₫

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Roxana Motel 6

Motel 6 Hazelwood, MO

Motel 6 Caseyville, IL - Caseyville Il

Motel 6 Troy, IL

Top Roxana Hotel Reviews

21C Museum Hotel St Louis

Explore a world of travel with Expedia