Search Holiday Rentals in San Ysidro

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Check prices for these dates

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for San Ysidro holiday rentals

Rooftop terrace
Sentral Gaslamp Quarter

Aparthotel in Downtown San Diego

Sentral Gaslamp Quarter
4.0 star property
9.2 out of 10, Wonderful, (608)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is 2.885.549 ₫
4.108.190 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Sentral Gaslamp Quarter
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio
City24 Hotel Little Italy Mission Hills

Aparthotel in Middletown

City24 Hotel Little Italy Mission Hills
4.5 star property
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Beach nearby
Coronado Beach Resort

Condo in Historic Downtown Coronado

Coronado Beach Resort
3.0 star property
9.0 out of 10, Wonderful, (753)
"This stay was one of our best yet! Highly recommend! Friendly staff. Great space"
United States
Sheree
The price is 5.171.423 ₫
5.688.566 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Coronado Beach Resort
Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace
Kasa Gaslamp Quarter San Diego

Aparthotel in Downtown San Diego

Kasa Gaslamp Quarter San Diego
3.5 star property
8.0 out of 10, Very good, (154)
"Everything was perfect about the room and location. The minor flaw was the stench in the lobby from the downstairs restaurant and bar. I loved staying here. "
United States
Chris
Kasa Gaslamp Quarter San Diego
Lobby sitting area
Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Aparthotel in Hillcrest

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
8.4 out of 10, Very good, (264)
"Overall good place."
United States
Isaac
The price is 2.700.022 ₫
3.044.275 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Outdoor pool
Kasa Little Italy San Diego

Aparthotel in Downtown San Diego

Kasa Little Italy San Diego
4.5 star property
9.6 out of 10, Exceptional, (355)
"Loved this place "
Canada
Ally
The price is 5.661.165 ₫
8.760.835 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Kasa Little Italy San Diego
House (5 Bedrooms) | Interior
San Diego Home: AC, Hot Tub, Covered Patio & BBQ

Cottage in Spring Valley

San Diego Home: AC, Hot Tub, Covered Patio & BBQ
3.0 star property
The price is 5.631.624 ₫
14.455.379 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
San Diego Home: AC, Hot Tub, Covered Patio & BBQ
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Ysidro Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"Staff members were very helpful. Nice property."
Veronica 5-night trip
Posted 6 hours ago
The DEXTRO Little Italy, BW Premier Collection

Frequently asked questions

Can I find holiday rentals in San Ysidro?

Yes, there are holiday rentals where you'll be only 14.2 mi (22.8 km) from San Diego Zoo, providing a more remote option to escape the hustle and bustle. Tourists like the array of shops and top-notch restaurants in San Ysidro. Leave time to check out the beaches and live music during your visit.

How many holiday rentals are there in San Ysidro?

With 3 Expedia holiday rentals, you're guaranteed to find just the right place for your San Ysidro stay.

What can I see and do in San Ysidro?

While exploring the area, visit family-friendly sights like San Diego Zoo, or get outside and enjoy nature at Balboa Park. While in the area, you can also visit popular places such as San Ysidro Border Crossing and Petco Park.

What are holiday rentals like in San Ysidro?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in San Ysidro. Holiday rentals offer extras like WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about a sanitised environment, a holiday rental can offer a sense of seclusion away from public hotel lifts and lobbies bustling with people while still allowing you to travel. You'll also have more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a popular choice for family trips or small group gatherings.