Sant' Ambrogio Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Historic Centre of Florence

Historic Centre of Florence

10 out of top 10 points of interest in this area

Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral and stunning river views.

Find hotels in Historic Centre of Florence

Top hotels in Sant' Ambrogio

Hotel Bodoni

Hotel Bodoni

2 out of 5
Via Martiri del Popolo, 27 Florence FI
The price is 2.954.976 ₫ per night from 26 Apr to 27 Apr
2.954.976 ₫
3.528.291 ₫ total
26 Apr - 27 Apr
includes taxes & fees
8.2/10 Very Good! (814 reviews)
Pretty sure this is a mom and pop shop so I'll be more generous and forgiving with my review. Overall the staff are amazing, the host who greeted me most days was charming and friendly, others are lovely too, save for one grumpy old man, but I think that's how old folks are. Rooms are clean. My room ...

Reviewed on 8 Apr 2026

Hotel Bodoni
Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26 Florence FI
The price is 3.648.063 ₫ per night from 21 Apr to 22 Apr
3.648.063 ₫
4.229.012 ₫ total
21 Apr - 22 Apr
includes taxes & fees
8.2/10 Very Good! (426 reviews)
This was our second stay at the same hotel after a long time. We chose it again because of its central location and being close to the central train station (about a 15 min walk). The Duomo is a few minutes away. The reception was very welcoming and let us keep our luggages as our room was being ...

Reviewed on 9 Apr 2026

Hotel Bavaria
B&B di Piazza del Duomo

B&B di Piazza del Duomo

Via Dell' Oriuolo 49 Florence FI
Fully refundableReserve now, pay when you stay
The price is 6.681.488 ₫ per night from 19 Apr to 20 Apr
6.681.488 ₫
7.720.061 ₫ total
19 Apr - 20 Apr
includes taxes & fees
9.2/10 Wonderful! (266 reviews)
Utmärkt läge, supertrevlig personal, frukost-kupongerna gällde två olika intilliggande caffér som också var väldigt bra! Rummet var väldigt bra och hade allt som man behövde, det var lyhört så man hörde ljud från gatan men vi kunde sova utan problem.

Reviewed on 6 Apr 2026

B&B di Piazza del Duomo
See all 512 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sant Ambrogio holiday package cost?
Maybe less than you might think — from just , in fact! By combining hotels, flights and car rentals into your own custom-built travel package, your getaway to Sant Ambrogio is only clicks away.
How do I get a cheap travel package to Sant Ambrogio?
Combining your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Sant Ambrogio holiday package makes it simple to arrange your perfect trip. With more than 550 airlines throughout the world to choose from, finding flights that suit your busy schedule won't be hard. On top of that, we've got over 1null000null000 hotel options globally to choose from. Talk about choice! No matter who you are, Expedia can show you the world.
Where should I stay in Sant Ambrogio?
A trip to Sant Ambrogio isn't complete until you've seen Cathedral of Santa Maria del Fiore and Ponte Vecchio. Book somewhere nearby for easy access to these popular attractions.
What are the top hotels in Sant Ambrogio?
Reserve a room at New Alfani. It's one of the area's most popular hotels. Another reputable option in Sant Ambrogio is Wine Apartments Florence Sangiovese.
How far in advance should I book my Sant Ambrogio holiday?
Travellers are generally able to compare international airfares on Expedia within 12 months of departure. Booking at the last minute? With a bit of luck, it's still possible to purchase an affordable ticket only weeks before your flight.
What does an Expedia Sant Ambrogio travel package include?
Expedia has everything you need to organise your Sant Ambrogio trip, but what your package looks like is your call. Choose from any combination of flights, hotels and rental cars. Searching for some activities to keep you on the move? Once you've made your booking, you can add them too. No matter your budget or style, there's a package deal to match your needs.
What should I know before booking a Sant Ambrogio travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, combine your flights, hotels and rental cars and save a pretty penny. Whatever kind of holiday you're planning, you'll find a package that fits your budget.
Can I choose my airline with a Sant Ambrogio Expedia holiday package?
Yes, the choice is yours. We have access to over 550 airlines throughout the world, so you can tailor your Sant Ambrogio holiday according to your budget and needs.
If I'm not able to travel, can I cancel my Sant Ambrogio holiday package?
Don't worry if you're rethinking your Sant Ambrogio holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realise life can sometimes throw you a curveball, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Popular places to visit

Piazza di Santa Maria Novella

Piazza di Santa Maria Novella

4.5/5(3 reviews)

After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the fascinating museums in this vibrant area.

Piazza di Santa Maria Novella
Cathedral of Santa Maria del Fiore

Cathedral of Santa Maria del Fiore

4.5/5(278 reviews)

Find out about the history of Cathedral of Santa Maria del Fiore, a well-known monument in Florence. Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Cathedral of Santa Maria del Fiore
Uffizi Gallery in Florence in Italy

Uffizi Gallery

4.5/5(327 reviews)

You can study the exhibits at Uffizi Gallery, a museum with a story of its own, during your trip to Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area.

Uffizi Gallery