Sant' Ambrogio Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Known for its fascinating museums, stunning cathedral and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Find hotels in Historic Centre of Florence

Top hotels in Sant' Ambrogio

Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26 Florence FI
The price is 1.597.870 ₫ per night from 1 Mar to 2 Mar
1.597.870 ₫
1.973.510 ₫ total
1 Mar - 2 Mar
includes taxes & fees
8.2/10 Very Good! (421 reviews)
The manager was very nice and efficient. The room was spacious. Very close to the Doumo ( We could see a litte of the dome from our window.)

Reviewed on 23 Feb 2026

Hotel Bavaria
Hotel Bodoni

Hotel Bodoni

2 out of 5
Via Martiri del Popolo, 27 Florence FI
The price is 1.771.113 ₫ per night from 26 Feb to 27 Feb
1.771.113 ₫
2.225.749 ₫ total
26 Feb - 27 Feb
includes taxes & fees
8.2/10 Very Good! (799 reviews)
Amenities. Bathroom too small and should be mentioned when booking

Reviewed on 25 Feb 2026

Hotel Bodoni
Hotel Regency

Hotel Regency

5 out of 5
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
The price is 7.204.430 ₫ per night from 28 Feb to 1 Mar
7.204.430 ₫
8.418.250 ₫ total
28 Feb - 1 Mar
includes taxes & fees
9.4/10 Exceptional! (444 reviews)
Amazing staff, great location large rooms

Reviewed on 24 Feb 2026

Hotel Regency
See all 521 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sant Ambrogio holiday package cost?
Maybe less than you might think — from just , in fact! By combining hotels, flights and car rentals into your own custom-built travel package, your getaway to Sant Ambrogio is only clicks away.
How do I get a cheap travel package to Sant Ambrogio?
Combining your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Sant Ambrogio holiday package makes it simple to arrange your perfect trip. With more than 550 airlines throughout the world to choose from, finding flights that suit your busy schedule won't be hard. On top of that, we've got over 1null000null000 hotel options globally to choose from. Talk about choice! No matter who you are, Expedia can show you the world.
Where should I stay in Sant Ambrogio?
A trip to Sant Ambrogio isn't complete until you've seen Cathedral of Santa Maria del Fiore and Ponte Vecchio. Book somewhere nearby for easy access to these popular attractions.
What are the top hotels in Sant Ambrogio?
Reserve a room at New Alfani. It's one of the area's most popular hotels. Another reputable option in Sant Ambrogio is Wine Apartments Florence Sangiovese.
How far in advance should I book my Sant Ambrogio holiday?
Travellers are generally able to compare international airfares on Expedia within 12 months of departure. Booking at the last minute? With a bit of luck, it's still possible to purchase an affordable ticket only weeks before your flight.
What does an Expedia Sant Ambrogio travel package include?
Expedia has everything you need to organise your Sant Ambrogio trip, but what your package looks like is your call. Choose from any combination of flights, hotels and rental cars. Searching for some activities to keep you on the move? Once you've made your booking, you can add them too. No matter your budget or style, there's a package deal to match your needs.
What should I know before booking a Sant Ambrogio travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, combine your flights, hotels and rental cars and save a pretty penny. Whatever kind of holiday you're planning, you'll find a package that fits your budget.
Can I choose my airline with a Sant Ambrogio Expedia holiday package?
Yes, the choice is yours. We have access to over 550 airlines throughout the world, so you can tailor your Sant Ambrogio holiday according to your budget and needs.
If I'm not able to travel, can I cancel my Sant Ambrogio holiday package?
Don't worry if you're rethinking your Sant Ambrogio holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realise life can sometimes throw you a curveball, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Popular places to visit

Piazza di Santa Maria Novella which includes a garden, heritage architecture and a church or cathedral

Piazza di Santa Maria Novella

After visiting Piazza di Santa Maria Novella, make a plan to see the other sights and activities in Florence. Stroll along the riverfront or experience the acclaimed art galleries in this vibrant area.

Piazza di Santa Maria Novella
Cathedral of Santa Maria del Fiore featuring religious elements, a church or cathedral and a city

Cathedral of Santa Maria del Fiore

Find out about the history of Florence when you take a trip to Cathedral of Santa Maria del Fiore. Experience the fascinating museums and acclaimed art galleries in this vibrant area.

Cathedral of Santa Maria del Fiore
Uffizi Gallery in Florence in Italy

Uffizi Gallery

You can study the exhibits at Uffizi Gallery, a museum with a story of its own, during your trip to Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Uffizi Gallery